The Institute for Clinical and Experimental Research® is focused on the development of new diagnostic assays in a wide range of disciplines. Researchers at the institute regularly publish in respected, peer-reviewed journals, give presentations at national and international organizations, author books and book chapters, and develop new tests.

There are 131 total entries for the year 2016.

Grossmann AH, Zhao H, Jenkins N, Zhu W, Richards JR, Yoo JH, Winter JM, Rich B, Mleynek TM, Li DY, Odelberg SJ. The small GTPase ARF6 regulates protein trafficking to control cellular function during development and in disease. Small GTPases. 1-12.

Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong Z, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, Woodman SE, Harbour JW, Thomas KR, Odelberg SJ, Ostanin K, Li DY. ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma. Cancer Cell. 29(6):889-904.

Erickson JA, Grenache DG. A chromogranin A ELISA absent of an apparent high-dose hook effect observed in other chromogranin A immunoassays. Clinica Chimica Acta 2016;452:120-123.

Sono-Koree NK, Crist RA, Frank EL, Rodgers GM, Smock KJ. A High-Performance Liquid Chromatography Method for the Serotonin Release Assay is Equivalent to the Radioactive Method. International Journal of Laboratory Hematology 2016;38(1):72-80.

Akbas N, Gonzalez G, Buffone GJ, Grenache DG, Devaraj S. A Library of Rare β1-Antitrypsin (AAT) Variant Phenotypes to Aid in the Diagnosis of AAT Deficiency. American Journal of Clinical Pathology 2016;146(3):289-93.

Yuzyuk T, Liu A, Thomas A, Wilson JE, De Biase I, Longo N, Pasquali M. A novel method for simultaneous quantification of alpha-Aminoadipic semialdehyde/Piperideine-6-carboxylate and Pipecolic acid in plasma and urine. Journal of Chromatography B 2016;1017-1018:145-52.

Tantravahi SK, Szankasi P, Khorashad JS, Dao KH, Kovacsovics T, Kelley TW, Deininger MW. A phase II study of the efficacy and determinants of response to 5-azacitidine (Vidaza) in patients with chronic myelomonocytic leukemia. Leukemia & Lymphoma 2016;57(10):2441-4.

Johnson-Davis KL, Sadler AJ, Genzen JR. A retrospective analysis of urine drugs of abuse immunoassay positivity rates at a national reference laboratory. Journal of Analytical Toxicology 2016;40(2):97-107.

Hobert JA, Liu A, Pasquali M. Acylglycine Analysis by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS). Current Protocols in Human Genetics 2016;91:17.25.1-17.25.

Zantek ND, Hayward CP, Simcox TG, Smock KJ, Hsu P, Van Cott EM. An assessment of the state of current practice in specialized coagulation laboratories. American Journal of Clinical Pathology 2016;146(3):378-83.

Goker-Alpan O, Longo N, McDonald M, Shankar SP, Schiffmann R, Chang P, Shen Y, Pano A. An open-label clinical trial of agalsidase alfa enzyme replacement therapy in children with Fabry disease who are naïve to enzyme replacement therapy. Drug Design, Development and Theory 2016;10:1771-81.

Dasgupta A, Khalil SA, Johnson-Davis KL. Analytical Performance Evaluation of a New Cobas Tacrolimus Assay on Cobas e411 Analyzer: Comparison of Values Obtained by the CMIA Tacrolimus Assay and a Liquid Chromatography Combined with Tandem Mass Spectrometric Method. Annals of Clinical and Laboratory Science 2016;46(2):204-8.

Peterson LK, Willis R, Harris NE, Branch DW, Tebo AE. Antibodies to Phosphatidylserine/prothrombin Complex in Antiphospholipid Syndrome: Analytical and Clinical Perspectives. Advances in Clinical Chemistry 2016;73:1-28.

Tebo AE, Haven TR, Jackson BR. Autoantibody Diversity in Paraneoplastic Syndromes and Related Disorders: The Need for a More Guided Screening Approach. Clinica Chemica Acta 2016;459:162-9.

Mundy SA, Krock BL, Mao R, Shen JJ. BRAT1-related disease-identification of a patient without early lethality. American Journal of Medical Genetics 2016;170(3):699-702.

Tardif KD, Pyne MT, Malmberg E, Lunt TC, Schlaberg R. Cervical Cytology Specimen Stability in Surepath Preservative and Analytical Sensitivity for HPV Testing with the cobas® and Hybrid Capture 2® Tests. PLoS One 2016;11(2):e0149611.

Lennartsson AK, Theorell T, Kushnir MM, Jonsdottir IH. Changes in DHEA-s levels during first year of treatment in patients with clinical burnout are related to health development. Biological Psychology 2016;120:28-34.

Kovacsovics-Bankowski M, Kelley TW, Efimova O, Kim SJ, Wilson A, Swierczek S, Prchal J. Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2V617F allelic burden. Experimental Hematology & Oncology 2016;5:28.

Pavlov IY, Carper J, Lázár-Molnár E, Delgado JC. Clinical laboratory application of a reporter-gene assay for measurement of functional activity and neutralizing antibody response to infliximab.. Clinica Chimica Acta 2016;453:147-53.

Tebo AE, Willis R, Jaskowski TD, Guerra M, Pierangeli SS, Salmon J, Petri M, Branch DW. Clinical significance and correlations between anti-β2 glycoprotein I IgA assays in antiphospholipid syndrome and/or systemic lupus erythematosus. Clinica Chimica Acta; International Journal of Clinical Chemistry 2016;460:107-113.

Agarwal AM, Nussenzveig RH, Reading NS, Patel JL, Sangle N, Salama ME, Prchal JT, Perkins SL, Yaish HM, Christensen RD. Clinical utility of next-generation sequencing in the diagnosis of hereditary haemolytic anaemias. British Journal of Haematology 2016;174(5):806-14.

De Biase I. Commentary. Clinical Chemistry 2016;62(8):1064.

Shen W, Szankasi P, Sederberg M, Schumacher JA, Frizzell KA, Gee EP, Patel JL, South ST, Xu X, Kelley TW. Concurrent detection of targeted copy number variants and mutations using a myeloid malignancy next generation sequencing panel allows comprehensive genetic analysis using a single testing strategy. British Journal of Hematology 2016;173(1):49-58.

Gill DM, Stenehjem DD, Parikh K, Merriman J, Sendilnathan A, Agarwal AM, Hahn AW, Gupta S, Tantravahi SK, Samlowski WE, Agarwal N. Conditional survival of metastatic renal cell carcinoma patients treated with high-dose interleukin-2. Ecancermedicalscience 2016;10:676.

Walker B, Powers-Fletcher MV, Schmidt RL, Hanson KE. Cost-Effectiveness Analysis of Multiplex PCR with Magnetic Resonance Detection versus Empiric or Blood Culture-Directed Therapy for Management of Suspected Candidemia. Journal of Clinincal Microbiology 2016;54(3):718-26.

Ardon O, Procter M, Mao R, Longo N, Landaud YE, Shilon-Hadass A, Gabis LV, Hoffmann C, Tzadok M, Heimer G, Sada S, Ben-Zeev B, Anikster Y. Creatine transporter deficiency: Novel mutations and functional studies. Molecular Genetics and Metabolism Reports 2016;8 (2016) 20–23.

Thurm A, Himelstein D, DʼSouza P, Rennert O, Jiang S, Olatunji D, Longo N, Pasquali M, Swedo S, Salomons GS, Carrillo N. Creatine Transporter Deficiency: Screening of Males with Neurodevelopmental Disorders and Neurocognitive Characterization of a Case. Journal of Developmental and Behavioral Pediatrics 2016;37(4):322-6.

Bunkhardt B, Meuller S, Tasneem K, Perkins SL. Current status and future detections of T-lymphoblastic lymphoma in children and adolescents. British Journal of Haematology 2016;173(4):545-59.

Gibson JF, Huang J, Liu KJ, Carlson KR, Foss F, Choi J, Edelson R, Hussong JW, Mohl R, Hill S, Girardi M. Cutaneous T-cell lymphoma (CTCL): Current practices in blood assessment and the utility of T-cell receptor (TCR)-Vβ chain restriction. Journal of the American Academy of Dermatology 2016;74(5):870-7.

Witt BL, Cohen MB, Chadwick BE, Stephenson PD, Abasolo P, Schmidt RL. Cytomorphology is often insufficient to categorize non-small-cell lung carcinoma on FNA specimens. Diagnostic Cytopathology 2016;44(2):73-9.

Cromar A, Lozier BK, Haven TR, Hill HR. Detection of Acetylcholine Receptor Blocking Antibodies by Flow Cytometry. American Journal of Clinical Pathology 2016;145(1):81-5.

Peterson LK, Jaskowski TD, Mayes MD, Tebo AE. Detection of Anti-U3-RNP/fibrillarin IgG Antibodies by Line Immunoblot Assay has Comparable Clinical Significance to Immunoprecipitation Testing in Systemic Sclerosis. Journal of Immunologic Research 2016;64(2):483-8.

Szankasi P, Schumacher JA, Kelley TW. Detection of BCR-ABL1 mutations that confer tyrosine kinase inhibitor resistance using massively parallel, next generation sequencing.. Annals of Hematology 2016;95(2):201-10.

Clark ZD, Frank EL. Development and implementation of an HPLC-ECD method for analysis of vitamin C in plasma using automatic alternating column regeneration. Practical Laboratory Medicine 2016;6:25-37.

Yang HS, Wu AHB, Johnson-Davis KL, Lynch KL. Development and validation of an LC-MS/MS sulfonylurea assay for hypoglycemia cases in the emergency department. Clinica Chimica Acta 2016;454:130-4.

Beal SG, Couturier MR, Gander RM, Doern CD. Diagnostic Algorithm for the Diagnosis of Pediatric Parasitic Gastroenteritis. Journal of Clinical Laboratory Analysis 2016;30(2):155-60.

Geiersbach K, Adey N, Welker N, Elsberry D, Malmberg E, Edwards S, Downs-Kelly E, Salama M, Bronner M. Digitally Guided Microdissection Aids Somatic Mutation Detection in Difficult to Dissect Tumors. Cancer Genetics 2016;209(1-2):42-9.

Ray JA, Kushnir MM, Rockwood AL, Meikle AW. Direct Measurement of Free Estradiol in Human Serum and Plasma by Equilibrium Dialysis-Liquid Chromatography-Tandem Mass Spectrometry. Methods in Molecular Biology 2016;1378:99-108.

Möller AT, Bäckström T, Söndergaard HP, Kushnir MM, Bergquist J, Helström L. Diurnal Variations of Endogenous Steroids in the Follicular Phase of the Menstrual Cycle. Neurochemistry and Neuropharmacology 2016;2:01.

Dasgupta A, Davis B, Slawson MH, Johnson-Davis KL. Effect of Carbamazepine 10, 11-Epoxide on Serum Carbamazepine Measurement Using a New CMIA Assay: Comparison of Values Obtained by Using PETINIA, CEDIA and Liquid Chromatography Combined with Tandem Mass Spectrometry. Annals of Clinical and Laboratory Science 2016;46(3):242-6.

Yuzyuk T, Thomas A, Viau K, Liu A, De Biase I, Botto LD, Pasquali M, Longo N. Effect of dietary lysine restriction and arginine supplementation in two patients with pyridoxine-dependent epilepsy. Molecular Genetics and Metabolism 2016;118(3):167-72.

Samadder NJ, Neklason DW, Boucher KM, Byrne KR, Kanth P, Samowitz W, Jones D, Tavtigian SV, Done MW, Berry T, Jasperson K, Pappas L, Smith L, Sample D, Davis R, Topham MK, Lynch P, Strait E, McKinnon W, Burt RW, Kuwada SK. Effect of Sulindac and Erlotinib vs Placebo on Duodenal Neoplasia in Familial Adenomatous Polyposis: A Randomized Clinical Trial. JAMA 2016;315(12):1266-75.

Herman DS, Ranjitkar P, Yamaguchi D, Grenache DG, Greene DN. Endogenous alkaline phosphatase interference in cardiac troponin I and other sensitive chemiluminescence immunoassays that use alkaline phosphatase activity for signal amplification. Clinical Biochemistry 2016;49(15):1118-1121.

Nerenz RD, Butch AW, Woldemariam GA, Yarbrough ML, Grenache DG, Gronowski AM.. Estimating the hCGβcf in urine during pregnancy. Clinical Biochemistry 2016;49(3):282-6.

Patel SB, Stenehjem DD, Gill DM, Tantravahi SK, Agarwal AM, Hsu J, Vuong W, Pal SK, Agarwal N. Everolimus Versus Temsirolimus in Metastatic Renal Cell Carcinoma After Progression With Previous Systemic Therapies. Clinical Genitourin Cancer 2016;14(2):153-9.

Langan PS, Close DW, Coates L, Rocha RC, Ghosh K, Kiss C, Waldo G, Freyer J, Kovalevsky A, Bradbury AR. Evolution and characterization of a new reversibly photoswitching chromogenic protein, Dathail. Journal of Molecular Biology 2016;428(9 Pt A):1776-89.

Harris RM, Couturier BA, Sample SC, Coulter KS, Casey KK, Schlaberg R. Expanded Geographic Distribution and Clinical Characteristics of Ehrlichia ewingii Infections, United States. Emerging Infectious Diseases 2016;22(5):862-5.

Pellatt DF, Stevens JR, Wolff RK, Mullany LE, Herrick JS, Samowitz W, Slattery ML. Expression Profiles of miRNA Subsets Distinguish Human Colorectal Carcinoma and Normal Colonic Mucosa. Clinical and Translational Gastroenterology 2016;7:e152.

Stenehjem DD, Toole M, Merriman J, Parikh K, Daignault S, Scarlett S, Esper P, Skinner K, Udager A, Tantravahi SK, Gill D, Straubhar AM, Agarwal AM, Grossmann KF, Samlowski WE, Redman B, Agarwal N, Alva A. Extension of overall survival beyond objective responses in patients with metastatic renal cell carcinoma treated with high-dose interleukin-2. Cancer Immunology, Immunotherapy: CII 2016;65(8):941-9.


Netzel BC, Grant RP, Hoofnagle AN, Rockwood AL, Shuford CM, Grebe SKG. First steps towards harmonization of LC-MS/MS thyroglobulin assays. Clinical Chemistry 2016;62(1):297-9.

Procter M, Wolf B, Mao R. FORTY-EIGHT NOVEL MUTATIONS CAUSING BIOTINIDASE DEFICIENCY. Molecular Genetics and Metabolism Reports 2016;117(3):369-72.

Underhill HR, Kitzman JO, Hellwig S, Welker NC, Daza R, Baker DN, Gligorich KM, Rostomily RC, Bronner MP, Shendure J. Fragment Length of Circulating Tumor DNA. PLoS Genetics 2016;12(7):e1006162.

Geiersbach KB, Willmore-Payne C, Pasi AV, Paxton CN, Werner TL, Xu X, Wittwer CT, Gulbahce HE, Downs-Kelly E. Genomic Copy Number Analysis of HER2-Equivocal Breast Cancers. American Journal of Clinical Pathology 2016;146(4):439-47.

Escobar H, Kushnir MM, Rockwood AL, Meikle AW. High Sensitivity Measurement of Pancreatic Polypeptide and Its Variant in Serum and Plasma by LC-MS/MS. Methods in Molecular Biology 2016;1378:199-210.

Kushnir MM, Nelson GJ, Frank EL, Rockwood AL. High-Throughput Analysis of Methylmalonic Acid in Serum, Plasma, and Urine by LC-MS/MS. Method for Analyzing Isomers Without Chromatographic Separation. Methods in Molecular Biology 2016;1378:159-73.

Profaizer T, Lázár-Molnár E, Close DW, Delgado JC, Kumánovics A. HLA genotyping in the clinical laboratory: comparison of next-generation sequencing methods. HLA 2016;88(1-2):14-24.

Diaz MH, Cross KE, Benitez AJ, Hicks LA, Kutty P, Bramley AM, Chappell JD, Hymas W, Patel A, Qi C, Williams DJ, Arnold SR, Ampofo K, Self, WS, Grijalva CG, Anderson EJ, McCullers JA, Pavia AT, Wunderink RG, Edwards KM, Jain S, Winchell JM. Identification of Bacterial and Viral Codetections With Mycoplasma pneumoniae Using the TaqMan Array Card in Patients Hospitalized With Community-Acquired Pneumonia. Open Forum Infectious Diseases 2016;3(2):ofw071.

Lázár-Molnár E, Delgado JC. Immunogenicity Assessment of Tumor Necrosis Factor Antagonists in the Clinical Laboratory. Clinical Chemistry 2016;62(9):1186-98.

Agarwal AM, Liew MA, Nussenzveig RH, Sangle N, Heikal N, Yaish H, Christensen R. Improved harmonization of Eosin -5-maleimide binding test across different instruments and age groups. Cytometry Part B: Clinical Cytometry 2016;90(6):512-516.

Rule, GS, Rockwood A. Improving quantitative precision and throughput by reducing calibrator use in LC-MS/MS. Analytica Chimica Acta 2016;919:1-94.

Nussenzveig RH, Pham HT, Perkins SL, Prchal JT, Agarwal AM, Salama ME. Increased frequency of coexisting JAK2 exon-12 or MPL exon-10 mutations in patients with low JAK2 V617F allelic burden. Leukemia and Lymphoma 2016;57(6):1429-35.

Kushnir MM, Rockwood AL, Strathmann FG, Frank EL, Straseski JA, Meikle AW. LC-MS/MS Measurement of Parathyroid Hormone Related Peptide. Clinical Chemistry 2016;62(1):218-26.

Reading NS, Shooter C, Song J, Miller R, Agarwal A, Clark B, Thein SL, Divoky V, Prchal JT. Loss of major DNase l hypersensitive sites in duplicated â-globin gene cluster incompletely silences HBB gene expression. Human Mutation 2016;37(11):1153-1156.

Johnson MB, Flanagan SE, Martins TB, Hill HR, Hattersley AT, McDonald TJ. Low IgE Is a Useful Tool to Identify STAT3 Gain-of-Function Mutations. Clinical Chemistry 2016;62(11):1536-1538.

Caanen WR, Kuijper EAM, Hompes PG, Kushnir MM, Rockwood AL, Meikle WA, Homburg R, Lambalk CB. Mass spectrometry methods measured androgen and estrogen concentrations during pregnancy and in newborns of mothers with polycystic ovary syndrome. European Journal of Endocrinology 2016;174(1):25-32.

Modzelewska K, Boer EF, Mosbruger TL, Picard D, Anderson D, Miles RR, Kroll M, Oslund W, Pysher TJ, Schiffman JD, Jensen R, Jette CA, Huang A, Stewart RA. MEK Inhibitors Reverse Growth of Embryonal Brain Tumors Derived from Oligoneural Precursor Cells. Cell Reports 2016;17(5):1255-1264.

Slattery ML, Herrick JS, Pellatt DF, Stevens JR, Mullany LE, Wolff E, Hoffman MD, Samowitz WS, Wolff RK.. MicroRNA profiles in colorectal carcinomas, adenomas, and normal colonic mucosa: variations in miRNA expression and disease progression. Carcinogenesis 2016;37(3):245-61.

Miles RR, Shah RK, Frazer JK. Molecular genetics of childhood, adolescent and young adult non-Hodgkin lymphoma. British Journal of Haematology 2016;173(4):582-96.

Best DH, Dames SA, Wooderchak-Donahue W, Lewis T, Sumner KL, Vaughn CP, Mao R, Farkas DH. Molecular pathology methods. Molecular Pathology in Clinical Practice 2016;19-52.

Sheffield BS, Kos Z, Asleh-Aburaya K, Wang XQ, Leung S, Gao D, Won J, Chow C, Rachamadugu R, Stijleman I, Wolber R, Gilks CB, Myles N, Thomson T, Hayes MM, Bernard PS, Nielsen TO, Chia SK. Molecular subtype profiling of invasive breast cancers weakly positive for estrogen receptor. Breast Cancer Research and Retreat 2016;155(3):483-90.

Schmidt RL, Hussong JW. Moriates C, Arora V, Shah N, eds. Understanding Value-Based Healthcare. American Journal of Clinical Pathology 2016;145(3):428-9.

Shaco-Levy R, Jasperson KW, Martin K, Samadder NJ, Burt RW, Ying J, Bronner MP. Morphologic characterization of hamartomatous gastrointestinal polyps in Cowden syndrome, Peutz-Jeghers syndrome, and juvenile polyposis syndrome. Human Pathology 2016;49:39-48.

Powers JL, Buys SS, Fletcher D, Melis R, Johnson-Davis K, Lyon E, Malmberg EM, McMillin GA. Multi-gene and Drug Interaction Approach for Tamoxifen Metabolite Patterns Reveals Possible Involvement of CYP2C9, CYP2C19 and ABCB1. Journal of Clinical Pharmacology 2016;56(12):1570-1581.

Hanson KE, Couturier MR. Multiplexed Molecular Diagnostics for Respiratory, Gastrointestinal and Central Nervous System Infections. Clinical Infectious Diseases 2016;63(10):1361-1367.

Klinger M, Zheng J, Elenitoba-Johnson KS, Perkins SL, Faham M, Bahler DW. Next-generation IgVH sequencing CLL-like monoclonal B-cell lymphocytosis reveals frequent oligoclonality and ongoing hypermutation. Leukemia 2016;30(5):1055-61.

Voelkerding KV, Coonrod EM, Durtschi JD, Margraf RL. Next-Generation Sequencing: Principles for Clinical Application. Molecular Pathology in Clinical Practice 2016;889-909.

Powers-Fletcher MV, Hanson KE. Nonculture Diagnostics in Fungal Disease. Infectious Disease Clinics of North America 2016;30(1):37-49.

Marin SJ, Doyle K, Chang A, Concheiro-Guisan M, Huestis MA, Johnson-Davis KL. One Hundred False-Positive Amphetamine Specimens Characterized by Liquid Chromatography Time-of-Flight Mass Spectrometry. Journal of Analytical Toxicology 2016;40(1):37-42.

Adler DG, Witt B, Chadwick B, Wells J, Taylor LJ, Dimaio C, Schmidt R. Pathologic evaluation of a new endoscopic ultrasound needle designed to obtain core tissue samples: A pilot study. Endoscopic Ultrasound 2016;5(3):178-83.

Meznarich J, Miles R, Paxton CN, Afify Z. Pediatric B-Cell Lymphoma With Lymphoblastic Morphology, TdT Expression, MYC Rearrangement, and Features Overlapping With Burkitt Lymphoma. Pediatric Blood & Cancer 2016;63(5):938-40.

La'ulu SL, Rasmussen KJ, Straseski JA. Pediatric Reference Intervals for Free Thyroxine and Free Triiodothyronine by Equilibrium Dialysis – Liquid Chromatography – Tandem Mass Spectrometry. Journal of Clinical Research in Pediatric Endocrinology 2016;8(1):26-31.

Erickson JA, Jensen RA, Grenache DG. Performance Evaluation of an ELISA for the Quantitative Measurement of β1-Antitrypsin in Stool. Journal of Applied Laboratory Medicine 2016;01:60-6.

Yan L, Salama ME, Lanciault C, Matsumura L, Troxell ML. Polyomavirus large T antigen is prevalent in urothelial carcinoma post-kidney transplant. Human Pathology 2016;48:122-31.

Hanson KE, Slechta ES, Killpack JA, Heyrend C, Lunt T, Daly JA, Hemmert AC, Blaschke AJ. Preclinical Assessment of a Fully Automated Multiplex PCR Panel for the Detection of Central Nervous System Pathogens. Journal on Clinical Microbiology 2016;54(3):785-7.

Longo N. Primary Carnitine Deficiency and Newborn Screening for Disorders of the Carnitine Cycle. Annals of Nutrition and Metabolism 2016;68 Suppl 3:5-9.

Barakauskas VE, Bradshaw TA, Smith LD, Lehman CM, Johnson-Davis KL. Process Optimization to Improve Immunosuppressant Drug Testing Turnaround Time. American Journal of Clinical Pathology 2016;146(2):182-90.

Martin M, Brase JC, Ruiz A, Prat A, Kronenwett R, Calvo L, Petry C, Bernard PS, Ruiz-Borrego M, Weber KE, Rodriguez CA, Alvarez IM, Segui MA, Perou CM, Casas M, Carrasco E, Caballero R, Rodriguez-Lescure A. Prognostic ability of EndoPredict compared to research-based versions of the PAM50 risk of recurrence (ROR) scores in node-positive, estrogen receptor-positive, and HER2-negative breast cancer. A GEICAM/9906 sub-study. Breast Cancer Research and Treatment 2016;156(1):81-9.

Gomez-Gelvez JC, Salama ME, Cogan C, Leavitt M, Perkins SL, Inamdar K. Prognostic Impact of Tumor Microenvironment on Diffuse Large B-Cell Lymphoma Treated with R-CHOP. American Journal of Clinical Pathology 2016;145(4):514-23.

Smock KJ, Plumhoff EA, Meijer P, Hsu P, Zantek ND, Heikal NM, Van Cott EA. Protein S testing in patients with protein S deficiency, factor V Leiden, and rivaroxaban by North American Specialized Coagulation Laboratories. Thrombosis and Haemostasis 2016;116(1):50-7.

Day RW, Clement PW, Hersh AO, Connors SM, Sumner KL, Best DH, Alashari M. Pulmonary veno-occlusive disease: Two children with gradual disease progression. Respiratory Medicine Case Reports 2016;20:82-86.

Marin SJ, McMillin GA. Quantitation of Buprenorphine, Norbuprenorphine, Buprenorphine Glucuronide, Norbuprenorphine Glucuronide and Naloxone in Urine by LC-MS/MS. Methods in Molecular Biology 2016;1383:69-78.

Slawson MH, Johnson-Davis KL. Quantitation of Carisoprodol and Meprobamate in Urine and Plasma Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). Methods in Molecular Biology 2016;1383:105-14.

Slawson MH, Johnson-Davis KL. Quantitation of Ethyl Glucuronide and Ethyl Sulfate in Urine using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). Clinical Applications of Mass Spectrometry: Methods & Protocols 2016;1383:167-75.

Slawson MH, Johnson-Davis KL. Quantitation of Flecainide, Mexiletine, Propafenone, and Amiodarone in Serum or Plasma Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). Methods in Molecular Biology 2016;1383:11-9.

Slawson MH, Johnson-Davis KL. Quantitation of Haloperidol, Fluphenazine, Perphenazine, and Thiothixene in Serum or Plasma Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). Methods in Molecular Biology 2016;1383:49-57.

Rule GS, Rockwood AL, Johnson-Davis KL. Quantitation of Teriflunomide in Human Serum/Plasma Across a 40,000-Fold Concentration Range by LC/MS/MS. Methods in Molecular Biology 2016;1383:195-203.

Marin SJ, McMillin GA. Quantitation of Total Buprenorphine and Norbuprenorphine in Meconium by LC-MS/MS. Methods in Molecular Biology 2016;1383:59-68.

Macmurdo CF, Wooderchak-Donahue W, Bayrak-Toydemir P, Le J, Wallenstein MB, Milla C, Teng JM, Bernstein JA, Stevenson DA. RASA1 somatic mutation and variable expressivity in capillary malformation/arteriovenous malformation (CM/AVM) syndrome. American Journal of Medical Genetics. Part A. 2016;170(6):1450-4.

Hackenmueller S, Grenache DG. Reference Intervals for Intestinal Disaccharidase Activities Determined from a Non-Reference Population. Journal of Applied Laboratory Medicine 2016;1(2):172-80.

Chindarkar NS, Chawla LS, Straseski JA, Jortani SA, Uettwiller-Geiger D, Orr RR, Kellum JA, Fitzgerald RL. Reference intervals of urinary acute kidney injury (AKI) markers [IGFBP7]∙[TIMP2] in apparently healthy subjects and chronic comorbid subjects without AKI. Clinica Chimica Acta 2016;452:32-7.

Koopmann M, Shea J, Kholmovski E, de Bever J, Minalga E, Holbrook M, Merrill R, Hadley JR, Owan T, Salama ME, Marrouche NF, Payne A.. Renal sympathetic denervation using MR-guided high-intensity focused ultrasound in a porcine model. Journal of Therapeutic Ultrasound 2016;4:03.

Self WH, Williams DJ, Zhu Y, Ampofo K, Pavia AT, Chappell JD, Hymas WC, Stockmann C, Bramley AM, Schneider E, Erdman D, Finelli L, Jain S, Edwards KM, Grijalva CG.. Respiratory Viral Detection in Children and Adults: Comparing Asymptomatic Controls and Patients With Community-Acquired Pneumonia. Journal of Infectious Diseases 2016;213(4):584-91.

Couturier MR. Revisiting the Roles of Culture and Culture-Independent Detection Tests for Campylobacter. Journal of Clinical Microbiology 2016;54(5):1186-8.

Christensen RD, Yaish HM, Nussenzveig RH, Agarwal AM. Siblings with severe pyruvate kinase deficiency and a complex genotype. American Journal of Medical Genetics. Part A 2016;170(9):2449-52.

Martins TB, Bandhauer ME, Wilcock DM, Hill HR, Slev PR. Specific Immunoglobulin (Ig) G Reference Intervals for Common Food, Insect, and Mold Allergens. Annals of Clinical and Laboratory Science 2016;46(6):635-638.

Li KD, Xu X, Matynia A. Systemic Mastocytosis with Associated Clonal Hematologic Non-mast Cell Lineage Disease (SM-AHNMD) with Chronic Myelogenous Leukemia and Complex Cytogenetics: A Case Report and Literature Review. Hematopathology 2016;1:61-68.

Wang SA, Tam W, Tsai AG, Arber DA, Hasserjian RP, Geyer JT, George TI, Czuchlewski DR, Foucar K, Rogers HJ, Hsi ED, Bryan Rea B, Bagg A, Dal Cin P, Zhao C, Kelley TW, Verstovsek S, Bueso-Ramos C, Orazi A. Targeted next-generation sequencing identifies a subset of idiopathic hypereosinophilic syndrome with features similar to chronic eosinophilic leukemia, not otherwise specified. Modern Pathology 2016;29(8):854-64.

Kelley TW, Arber DA, Gibson C, Jones D, Khoury JD, Medeiros BC, O'Malley DP, Patel KP, Pilichowska M, Vasef MA, Wallentine J, Zehnder JL. Template for Reporting Results of Biomarker Testing of Specimens From Patients With Myeloproliferative Neoplasms. Archives of Pathology and Laboratory Medicine 2016;140(7):675-7.

Kelley TW, Arber DA, Gibson C, Jones D, Khoury JD, Medeiros BC, O'Malley DP, Patel KP, Pilichowska M, Vasef MA, Wallentine J, Zehnder JL. Template for Reporting Results of Monitoring Tests for Patients With Chronic Myelogenous Leukemia (BCR-ABL1(+)). Archives of Pathology and Laboratory Medicine 2016;140(7):672-4.

Van Cott EM, Smock KJ, Chen D, Hsu P, Zantek ND, Meijer P. Testing for dabigatran and rivaroxaban by clinical laboratories. American Journal of Hematology 2016;91(11):E464-E467.

Rossi A, Couturier MR. The Brief Case: Cryptosporidiosis in a Severely Immunocompromised HIV Patient. Journal of Clinical Microbiology 2016;54(9):2219-21.

Smock KJ. The role of ADAMTS13 testing in the workup of suspected thrombotic thrombocytopenic purpura. Clinical Laboratory News 2016;42(4):10-14.

Joseph L, Cankovic M, Caughron S, Chandra P, Emmadi R, Hagenkord J, Hallam S, Jewell KE, Klein RD, Pratt VM, Rothberg PG, Temple-Smolkin RL, Lyon E. The Spectrum of Clinical Utilities in Molecular Pathology Testing Procedures for Inherited Conditions and Cancer: A Report of the Association for Molecular Pathology. The Journal of Molecular Diagnostics: JMD 2016;18(5):605-19.

Hartung AM, Swensen J, Uriz IE, Lapin M, Kristjansdottir K, Petersen US, Bang JM, Guerra B, Andersen HS, Dobrowolski SF, Carey JC, Yu P, Vaughn C, Calhoun A, Larsen MR, Dyrskjøt L, Stevenson DA, Andresen BS. The Splicing Efficiency of Activating HRAS Mutations Can Determine Costello Syndrome Phenotype and Frequency in Cancer. PLoS Genetics 2016;12(5):e1006039.

Ware AL, Malmberg E, Delgado JC, Hammond ME, Miller DV, Stehlik J, Kfoury A, Revelo MP, Eckhauser A, Everitt MD. The use of circulating donor specific antibody to predict biopsy diagnosis of antibody-mediated rejection and to provide prognostic value after heart transplantation in children. The Journal of Heart and Lung Transplantation 2016;35(2):179-85.

Li KD, Salama ME. Therapy Effect: Impact on Bone Marrow Morphology. Surgical Pathology Clinics 2016;9(1):177-87.

Ráez-Bravo A, Granados JE, Cano-Manuel FJ, Soriguer RC, Fandos P, Pérez JM, Pavlov IY, Romero D. Toxic and Essential Element Concentrations in Iberian Ibex (Capra pyrenaica) from the Sierra Nevada Natural Park (Spain): Reference Intervals in Whole Blood. Bulletin of Environmental Contamination and Toxicology 2016;96(3):273-80.

Zhou Z, Reyes-Vargas E, Escobar H, Rudd B, Rockwood AL, Delgado JC, He X, Jensen PE. Type 1 diabetes associated HLA-DQ2 and DQ8 molecules are relatively resistant to HLA-DM mediated release of invariant chain-derived CLIP peptides. European Journal of Immunology 2016;46(4):834-45.

Graf EH, Simmon KE, Tardif KD, Hymas W, Flygare S, Eilbeck K, Yandell M, Schlaberg R. Unbiased Detection of Respiratory Viruses Using RNA-seq-Based Metagenomics: A Systematic Comparison to A Commercial PCR Panel. Journal of Clinical Microbiology 2016;54(4):1000-7.

Schulte S, Rasmussen NN, McBeth JW, Richards PQ, Yochem E, Petron DJ, Strathmann FG. Utilization of the clinical laboratory for the implementation of concussion biomarkers in collegiate football and the necessity of personalized and predictive athlete specific reference intervals. The EPMA Journal 2016;7:01.

Liew M, Rowe L, Clement PW, Miles RR, Salama ME. Validation of break apart and fusion MYC probes using a digital FISH capture and imaging system. Journal of Pathology Informatics 2016;7:20.

Frigeni M, Iacobazzi F, Yin X, Longo N. Wide tolerance to amino acids substitutions In the OCTN1 ergothioneine transporter. Biochimica et Biophysica Acta 2016;1860(6):1334-42.

Bhat G, LaGrave D, Millson A, Herriges J, Lamb AN, Matalon R. Xq11.1-11.2 deletion involving ARHGEF9 in a girl with autism spectrum disorder. European Journal of Medical Genetics 2016;59(9):470-3.