The Institute for Clinical and Experimental Research® is focused on the development of new diagnostic assays in a wide range of disciplines. Researchers at the institute regularly publish in respected, peer-reviewed journals, give presentations at national and international organizations, author books and book chapters, and develop new tests.

There are 146 total entries for the year 2015.

Lloyd IE, Rowe LR, Erickson LK, Paxton CN, South ST, Alashari M. Two cases of Scimitar syndrome associated with multiple congenital skeletal anomalies and lacking abnormalities by genomic microarray analysis. Pediatric and Development Pathology 2015;17(5):360–5.

Walker BS, Nelson RE, Jackson BR, Grenache DG, Ashwood ER, Schmidt RL. A Cost-Effectiveness Analysis of First Trimester Non-Invasive Prenatal Screening for Fetal Trisomies in the United States. PLoS One 2015;10(7):e0131402.

Dames S, Eilbeck K, Mao R A high-throughput next-generation sequencing assay for the mitochondrial genome. Methods in Molecular Biology 2015;1264:77-88.

McMillin GA, Marin SJ, Johnson-Davis KL, Lawlor BG, Strathmann FG. A Hybrid Approach to Urine Drug Testing using High Resolution Mass Spectrometry and Select Immunoassays. American Journal of Clinical Pathology 2015;143(2):234-40.

Chen ZW, Perkins SL, Weiss RL, Bahler DW, Hussong JW, Salama ME. A limited plasma cell flow cytometry panel with reflex CD138 immunohistochemistry is an optimal workflow process for evaluating plasma cell neoplasms in bone marrow specimens. American Journal for Clinical Pathology 2015;143(1):78-83.

Schmidt RL, Kordy MA, Genzen JR, Straseski JA, Greene DN, Lehman CM. A mathematical procedure to estimate the impact of a change in method on discordance or misclassification at a decision limit in laboratory method comparison studies. Clinica Chimica Acta 2015;440:23-30.

Schumacher JA, Reading NS, Szankasi P, Matynia AP, Kelley TW. A novel approach to quantitating leukemia fusion transcripts by qRT-PCR without the need for standard curves. Experimental and Molecular Pathology 2015;99(1):104-108.

Lip GY, Halperin JL, Petersen P, Rodgers GM, Pall D, Renfurm RW. A Phase II, double-blind, randomized, parallel group, dose-finding study of the safety and tolerability of darexaban compared with warfarin in patients with non-valvular atrial fibrillation: the oral factor Xa inhibitor for prophylaxis of stroke in atrial fibrillation study 2 (OPAL-2). Journal of Thrombosis and Haemostasis 2015;13(8):1405-13.

Schmidt RL, Straseski JA, Raphael KL, Adams AH, Lehman CM. A Risk Assessment of the Jaffe vs Enzymatic Method for Creatinine Measurement in an Outpatient Population. PLoS One 2015;10(11):e0143205.

Brown-Elliott BA, Hanson K, Vasireddy S, Iakhiaeva E, Nash KA, Vasireddy R, Parodi N, Smith T, Gee M, Strong A, Barker A, Cohen S, Muir H, Slechta ES, Wallace RJ Jr. Absence of a functional erm gene in isolates of Mycobacterium immunogenum and the Mycobacterium mucogenicum group, based on in vitro clarithromycin susceptibility. Journal of Clinical Microbiology 2015;53(3):875-8.

Bentley MJ, Rodgers GM. Acute renal failure is prevalent in patients with thrombotic thrombocytopenic purpura associated with low plasma ADAMTS13 activity: comment. Journal of Thrombosis and Haemostasis 2015;13(8):1524-5.

Lee M, Keener J, Xiao J, Long Zheng X, Rodgers GM. ADAMTS13 and its variants promote angiogenesis via upregulation of VEGF and VEGFR2. Cellular and Molecular Life Sciences 2015;72(2):349-56.

Greene DN, Vaughn CP, Crews BO, Agarwal AM. Advances in detection of hemoglobinopathies. Clinica Chemica Acta 2015;439C:50-57.

Tamari R, Mughal TI, Rondelli D, Hasserjian R, Gupta V, Odenike O, Fauble V, Finazzi G, Pane F, Mascarenhas J, Prchal J, Giralt S, Hoffman R. Allo-SCT for myelofibrosis: reversing the chronic phase in the JAK inhibitor era? Bone Marrow Transplantation 2015;50(5):628-636.

Rule GS, Rockwood AL. Alternative for reducing calibration standard use in mass spectrometry. Clinical Chemistry 2015;61(2):431-3.

Summers SJ, Patel DP, Hamilton BD, Presson AP, Fisher MA, Lowrance WT, Southwick AW. An antimicrobial prophylaxis protocol using rectal swab cultures for transrectal prostate biopsy. World Journal of Urology 2015;33(12):2001-7.

Slattery ML, Herrick JS, Mullany LE, Valeri N, Stevens J, Caan BJ, Samowitz W, Wolff RK. An evaluation and replication of miRNAs with disease stage and colorectal cancer-specific mortality. International Journal of Cancer 2015;137(2):428-38.

Rule GS, Rockwood AL, Johnson-Davis KL. LC-MS/MS Method for Determination of Teriflunomide, Over a 40,000-Fold Dynamic Range Using Overlapping Calibrators. Therapeutic Drug Monitoring 2015;37(4):472-8.

Lloyd IE, Clement PW, Salzman KL, Jensen RL, Salama ME, Palmer CA. An unusual and challenging case of HIV-associated primary CNS Lymphoma with Hodgkin-like morphology and HIV encephalitis. Diagnostic Pathology 2015;10(1):152.

Sowder AM, Yarbrough ML, Nerenz RD, Mitsios JV, Mortensen R, Gronowski AM, Grenache DG. Analytical performance evaluation of the i-STAT Total ß-human chorionic gonadotropin immunoassay. Clinica Chimica Acta 2015;446:165-170.

Kwan ML, Kroenke CH, Sweeney C, Bernard PS, Weltzien EK, Castillo A, Factor RE, Maxfield KS, Stijleman IJ, Kushi LH, Quesenberry CP, Habel LA, Caan BJ. Association of high obesity with PAM50 breast cancer intrinsic subtypes and gene expression. BMC Cancer 2015;15(1):278.

Lazar-Molnar E, Tebo AE. Autoimmune NMDA receptor encephalitis. Clinica Chimica Acta 2015;438:90-97.

Factor RE, Schmidt RL, Chadwick BE, Witt BJ, Morgan M, Neumayer LA, Layfield LJ. Axillary lymph node FNA in women with breast cancer is a highly accurate procedure, so why are core biopsies being done? Diagnostic Cytopathology 2015;43(6):510-2.

Signorelli H, Straseski JA, Genzen JR, Walker BS, Jackson BR, Schmidt RL. Benchmarking to Identify Practice Variation in Test Ordering: A Potential Tool for Utilization Management. Laboratory Medicine 2015;46(4):356-64.

Campo RA, Light KC, O'Connor K, Nakamura Y, Lipschitz D, LaStayo PC, Pappas LM, Boucher KM, Irwin MR, Hill HR, Martins TB, Agarwal N, Kinney AY. Blood pressure, salivary cortisol, and inflammatory cytokine outcomes in senior female cancer survivors enrolled in a tai chi chih randomized controlled trial. Journal of Cancer Survivorship 2015;9(1):115-25.

Owen WE, Thatcher ML, Crabtree KJ, Greer RW, Strathmann FG, Straseski JA, Genzen JG. Body Fluid Matrix Evaluation on a Roche cobas 8000 System. Clinical Biochemistry 2015;48(13-14):911-4.

Kwan ML, Bernard PS, Kroenke CH, Factor RE, Habel LA, Weltzien EK, Castillo A, Gunderson EP, Maxfield KS, Stijleman IJ, Langholz BM, Quesenberry CP Jr, Kushi LH, Sweeney C, Caan BJ. Breastfeeding, PAM50 Tumor Subtype, and Breast Cancer Prognosis and Survival. Journal of the National Cancer Institute 2015;107(7).

Pusch T, Fisher MA, Gander RM. Cardiobacterium valvarum, an Emerging New HACEK Organism, as the Causative Agent of Infective Endocarditis: Case Report and Review of the Literature. Clinical Microbiology Newsletter 2015;37(16)127-32.

Javan H, Szuscik AM, Li L, Schaaf CL, Salama ME, Selzman CH. Cardiomyocyte p65 nuclear factor-?B is necessary for Compensatory Adaptation to Pressure-Overload. Circulation, Heart Failure 2015;8(1):109-18.

Terry MR, Arya R, Mukhopadhyay A, Berrett KC, Clair PM, Witt B, Salama ME, Bhutkar A, Oliver TG. Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo. Cell Death and Differentiation 2015;22(5):719-30.

Yousef S, Kovacsovics-Bankowski M, Salama ME, Bhardwaj N, Steinbach M, Langemo A, Kovacsovics T, Marvin J, Binder M, Panse J, Kröger N, Luetkens T, Atanackovic D. CD229 is expressed on the surface of plasma cells carrying an aberrant phenotype and chemotherapy-resistant precursor cells in multiple myeloma. Human Vaccines and Immunotherapeutics 2015;11(7):1606-11.

Couturier BA, Jensen R, Arias N, Heffron M, Gubler E, Case K, Gowans J, Couturier MR. Clinical and Analytical Evaluation of a Single-Vial Stool Collection Device with Formalin-Free Fixative for Improved Processing and Comprehensive Detection of Gastrointestinal Parasites. Journal of Clinical Microbiology 2015;53(8):2539-48. doi.

Grenache DG, Heichman KA, Werner TL, Vucetic Z. Clinical performance of two multi-marker blood tests for predicting malignancy in women with an adnexal mass. Clinica Chimica Acta 2015;438:358-63.

Li KD, Miles R, Tripp SR, Glenn MJ, Perkins SL, Salama M. Clinicopathologic evaluation of MYC expression in primary mediastinal (thymic) large B-cell lymphoma. American Journal for Clinical Pathology 2015;143(4):598-604.

Tebo AE. Commentary. Clinical Chemistry 2015;61(9):1136-7.

King KY, Matatall KA, Shen CC, Goodell MA, Swierczek SI, Prchal JT. Comparative long-term effects of interferon a and hydroxyurea on human hematopoietic progenitor cells. Experimental Hematology 2015;43(10):912-918.

Büttler RM, Martens F, Fanelli F, Pham HT, Kushnir MM, Janssen MJ, Owen L, Taylor AE, Soeborg T, Blankenstein MA, Heijboer AC. Comparison of 7 Published LC-MS/MS Methods for the Simultaneous Measurement of Testosterone, Androstenedione, and Dehydroepiandrosterone in Serum. Clinical Chemistry 2015;61(12):1475-83.

Marin SJ, Sawyer JC, Xiang H, Johnson-Davis KL. Comparison of drug detection by three quadrupole time-of-flight mass spectrometry platforms. Journal of Analytical Toxicology 2015;39(2):89-95.

Sergueeva AI, Miasnikova GY, Polyakova LA, Nouraie M, Prchal JT, Gordeuk VR. Complications in children and adolescents with Chuvash polycythemia. Blood 2015;125(2):414-5.

Zhou L, Palais RA, Paxton CN, Geiersbach KB, Wittwer CT. Copy number assessment by competitive PCR with limiting deoxynucleotide triphosphates and high-resolution melting. Clinical Chemistry 2015;61(5):724-33.

Bailey EB, Tantravahi SK, Poole A, Agarwal AM, Straubhar AM, Batten JA, Patel SB, Wells CE, Stenehjem DD, Agarwal N. Correlation of degree of hypothyroidism with survival outcomes in patients with metastatic renal cell carcinoma receiving vascular endothelial growth factor receptor tyrosine kinase inhibitors. Clinical Genitourinary Cancer 2015;13(3):e131-7.

Hanson KE, Swaminathan S. Cytomegalovirus antiviral drug resistance: future prospects for prevention, detection and management. Future Microbiology 2015;10:1545-8.

Chindarkar NS, Chawla LS, Straseski JA, Jortani SA, Uettwiller-Geiger D, Orr RR, Kellum JA, Fitzgerald RL. Demographic data for urinary Acute Kidney Injury (AKI) marker [IGFBP7]·[TIMP2] reference range determinations. Data in Brief 2015;5:888-92.

Lozier BK, Haven TR, Astill ME, Hill HR. Detection of Acetylcholine Receptor Modulating Antibodies by Flow Cytometry. American Journal of Clinical Pathology 2015;143(2):186-92.

Liew M, Mao R, Wittwer CT, Salama ME. Detection of chromosomal translocations in formalin-fixed paraffin-embedded (FFPE) leukemic specimens by digital expression profiling. International Journal of Laboratory Hematology 2015;37(5):690-8.

Lu J, Pulsipher BS, Grenache DG. Development of an enzymatic assay to measure lactate in perchloric acid-precipitated whole blood. Clinica Chimica Acta 2015;444:208-211.

Romero ST, Geiersbach KB, Paxton CN, Rose NC, Schisterman EF, Branch DW, Silver RM. Differentiation of genetic abnormalities in early pregnancy loss Ultrasound in Obstetrics & Gynecology 2015;45(1):89-94.

Rifai N, Topol E, Chan E, Lo YM, Wittwer CT. Disruptive Innovation in Laboratory Medicine. Clinical Chemistry 2015;61(9):1129-32.

Siryani I, Jama M, Rumman N, Marzouqa H, Kannan M, Lyon E, Hindiyeh M. Distribution of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mutations in a Cohort of Patients Residing in Palestine. PLoS One 2015;10(7):e0133890.

Cohen A, Sato M, Aldape K, Mason CC, Alfaro-Munoz K, Heathcock L, South ST, Abegglen LM, Schiffman JD, Colman H. DNA copy number analysis of Grade II-III and Grade IV gliomas reveals differences in molecular ontogeny including chromothripsis associated with IDH mutation status. Acta Neuropathologica Communications 2015;3(1):34.

Nelson RE, Stockmann C, Hersh AL, Pavia AT, Korgenksi K, Daly JA, Couturier MR, Ampofo K, Thorell EA, Doby EH, Robison JA, Blaschke AJ. Economic analysis of rapid and sensitive polymerase chain reaction testing in the emergency department for influenza infections in children. Pediatric Infections Disease Journal 2015;34(6):577-82.

Little RR, La'ulu SL, Hanson SE, Rohlfing CL, Schmidt RL. Effects of 49 Different Rare Hb Variants on HbA1c Measurement in Eight Methods. Journal of Diabetes Science and Technology 2015;9(4):849-56.

Desai DS, Lyon E, Rodgers GM, Jama MA, Wallentine SL, Smock KJ. Elderly female with a person and family history of a bleeding disorder. Clinical Chemistry 2015;61(7):909-12.

Christensen RD, Lambert DK, Henry E, Yaish HM, Prchal JT. End-tidal carbon monoxide as an indicator of the hemolytic rate. Blood Cells, Molecules, and Diseases 2015;54(3):292-6.

Johnson-Davis KL, Slawson MH. Ethyl glucuronide Positivity Rate in a Pain management population. Journal of Analytical Toxicology 2015;39(9):686-90.

Christensen RD, Agarwal AM, Nussenzveig RH, Heikal N, Liew MA, Yaish HM. Evaluating eosin-5-maleimide binding as a diagnostic test for hereditary spherocytosis in newborn infants. Journal of Perinatology 2015;35(5):357-61.

Samowitz WS. Evaluation of colorectal cancers for Lynch syndrome: practical molecular diagnostics for surgical pathologists. Modern Pathology 2015;28 Suppl 1:S109-13.

Jedrzkiewicz J, Call TR, Tripp SR, Witt BL. Evaluation of Mu Opioid Receptor Expression via Immunohistochemistry in Various Tumor Types. Kei Journal 2015;Vol 2, No 2.

Sant DW, Margraf RL, Stevenson DA, Grossmann AH, Viskochil DH, Hanson H, Everitt MD, Rios JJ, Elefteriou F, Hennessey T, Mao R. Evaluation of somatic mutations in tibial pseudarthrosis samples in neurofibromatosis type 1. American Journal of Medical Genetics 2015;52(4):256-61.

Scholes KL, La'ulu SL, Ence AT, Logan HK, Parker RL, Strathmann FG, Genzen JG. Evaluation of test strips for the rapid identification of ethylenediaminetetraacetic acid (EDTA) specimens. Laboratory Medicine 2015;46(2):97-108.

Johnson-Davis KL, Juenke JM, Thomas RL, Bradshaw T. Everolimus method comparison between Waters MassTrak™ Immunosuppressants XE (IUO) kit and an in-house laboratory developed LC-MS/MS method in renal transplant patients. Annals of Clinical Laboratory Science 2015;45(1):27-31.

Arthur H, Geisthoff U, Gossage JR, Hughes CC, Lacombe P, Meek ME, Oh P, Roman BL, Trerotola SO, Velthuis S, Wooderchak-Donahue W. Executive summary of the 11th HHT international scientific conference. Angiogenesis 2015;18(4):511-24.

George SA, Sciuto KJ, Lin J, Salama ME, Keener JP, Gourdie RG, Poelzing S. Extracellular sodium and potassium levels modulate cardiac conduction in mice heterozygous null for the Connexin43 gene. Pflügers Archiv 2015;467(11):2287-97.

Farrar JS, Wittwer CT. Extreme PCR: efficient and specific DNA amplification in 15-60 seconds. Clinical Chemistry 2015;61(1):145-53.

Gundlapalli AV, Scalchunes C, Boyle M, Hill HR. Fertility, pregnancies and outcomes reported by females with common variable immune deficiency and hypogammaglobulinemia: results from an internet-based survey. Journal of Clinical Immunology 2015;35(2):125-34.

de Dios A, Jacob S, Tayal A, Fisher MA, Dingle TC, Hamula CL.. First Report of Wohlfahrtiimonas chitiniclastica Isolation from a Patient with Cellulitis in the United States. Journal of Clinical Microbiology 2015;53(12):3942-4.

Prchal JT. Genetic selection by high altitude: Beware of experiments at ambient conditions. Proceedings of the National Academy of Sciences of the United States of America 2015;112(33):10080-1.

Frigerio A, Wright K, Wooderchak-Donahue W, Tan OT, Margraf R, Stevenson DA, Grimmer JF, Bayrak-Toydemir P. Genetic Variants Associated with Port-Wine Stains. PLoS One 2015;10(7):e0133158.

Walker AE, Henson GD, Reihl KD, Morgan RG, Dobson PS, Nielson EI, Ling J, Mecham RP, Li DY, Lesniewski LA, Donato AJ. Greater impairments in cerebral artery compared with skeletal muscle feed artery endothelial function in a mouse model of increased large artery stiffness. Journal of Physiology 2015593(8):1931-43.

Pyne MT, Mallory M, Hillyard DR. HCV RNA measurement in samples with diverse genotypes using versions 1 and 2 of the Roche COBAS® AmpliPrep/COBAS® TaqMan® HCV test. Journal of Clinical Virology 2015;65:54-57.

McDonald J, Wooderchak-Donahue W, VanSant Webb C, Whitehead K, Stevenson DA, Bayrak-Toydemir P. Hereditary hemorrhagic telangiectasia: genetics and molecular diagnostics in a new era. Frontiers in Genetics 2015;6:1.

Song J, Yoon D, Christensen RD, Horvathova M, Thiagarajan P, Prchal JT. HIF-mediated increased ROS from reduced mitophagy and decreased catalase causes neocytolysis. Journal of Molecular Medicine (Berlin) 2015;v93(8):857-66.

Pyne MT, Hamula CL, Tardif K, Law C, Schlaberg R. High-risk HPV detection and genotyping by APTIMA HPV using cervical samples. Journal of Virological Methods 2015;221:95-99.

Rubach MP, Hanson KE. ID Learning Unit-Diagnostics Update: Current Laboratory Methods for Rapid Pathogen Identification in Patients With Bloodstream Infections. Open Forum Infectious Diseases 2015;2(4):ofv174.

Scholes KL, Ence AT, Strathmann FG, Genzen JR. Identification and Characterization of EDTA Test Strip Interfering Substances Using a Digital Color Detector. Clinical Laboratory 2015;61(7):785-91.

Khot PD, Bird BA, Durrant R, Fisher MA. Identification of Nocardia Species by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry. Journal of Clinical Microbiology 2015;53(10):3366-9.

Zhang YV, Rockwood A. Impact of automation on mass spectrometry. Clinica Chimica Acta 2015;450:298-303.

Shiramizu B, Goldman S, Smith L, Agsalda-Garcia M, Galardy P, Perkins SL, Frazer JK, Sanger W, Anderson JR, Gross TG, Weinstein H, Harrison L, Barth MJ, Mussolin L, Cairo MS. Impact of persistent minimal residual disease post-consolidation therapy in children and adolescents with advanced Burkitt leukaemia: a Children's Oncology Group Pilot Study Report. British Journal of Haematology 2015;170(3):367-71.

Brown KA, Fenn JP, Freeman VS, Fisher PB, Genzen JR, Goodyear N, Houston ML, O'Brien ME, Tanabe P, ASCP Board of Certification Research and Development Committee. Impact of Time Lapse on ASCP Board of Certification Medical Laboratory Scientist (MLS) and Medical Laboratory Technician (MLT) Examination Scores.Laboratory Medicine 2015;46(3):e53-8.

MacNeil SM, Johnson WE, Li DY, Piccolo SR, Bild AH. Inferring pathway dysregulation in cancers from multiple types of omic data. Genome Medicine 2015;7(1):61.

Baughn LB, Biegel JA, South ST, Smolarek TA, Volkert S, Carroll AJ, Heerema NA, Rabin KR, Zweidler-McKay PA, Loh M, Hirsch B. Integration of cytogenomic data for furthering the characterization of pediatric B-cell acute lymphoblastic leukemia: a multi-institution, multi-platform microarray study. Cancer Genetics 2015;208(1-2):1-1.

Sandlund JT, Guillerman RP, Perkins SL, Pinkerton CR, Rosolen A, Patte C, Reiter A, Cairo MS. International Pediatric Non-Hodgkin Lymphoma Response Criteria. Journal of Clinical Oncology 2015;33(18):2106-11.

Gleicher N, McCulloh DH, Kushnir VA, Ganguly N, Barad DH, Goldman K, Kushnir MM, Albertini DF, Grifo J. Is there an androgen level threshold for aneuploidy risk in infertile women? Journal of Clinical Endocrinology and Metabolism. 2015;13:38.

Heikal NM, Jaskowski TD, Malmberg E, Lakos G, Branch DW, Tebo AE. Laboratory evaluation of anti-phospholipid syndrome: a preliminary prospective study of phosphatidylserine/prothrombin antibodies in an at-risk patient cohort. Clinical and Experimental Immunology 2015;180(2):218-26.

Thompson MD, Grubbs CJ, Bode AM, Reid JM, McGovern R, Bernard PS, Stijleman IJ, Green JE, Bennett C, Juliana MM, Moeinpour F, Steele VE, Lubet RA. Lack of effect of metformin on mammary carcinogenesis in nondiabetic rat and mouse models. Cancer Prevention Research 2015;(3):231-9.

Pomicter AD, Eiring AM, Senina AV, Zabriskie MS, Marvin JE, Prchal JT, O'Hare T, Deininger MW. Limited efficacy of BMS-911543 in a murine model of Janus kinase 2 V617F myeloproliferative neoplasm. Experimental Hematology 2015;43(7):537-545.

Owen WE, Caron JE, Genzen JG. Liver function testing on the Abaxis Piccolo Xpress: Use in Ebola virus disease protocols. Clinica Chimica Acta 2015;446:119-127.

Schniedewind B, Niederlechner S, Galinkin JL, Johnson-Davis KL, Christians U, Meyer EJ. Long-term cross-validation of everolimus therapeutic drug monitoring assays: the Zortracker study. Therapeutic Drug Monitoring 2015;37(3):296-303.

Longo N, Arnold GL, Pridjian G, Enns GM, Ficicioglu C, Parker S, Cohen-Pfeffer JL. Long-term safety and efficacy of sapropterin: the PKUDOS registry experience. Molecular Genetics and Metabolism 2015;114(4):557-63.

Lennartsson AK, Theorell T, Kushnir MM, Jonsdottir IH. Low levels of dehydroepiandrosterone sulfate in younger burnout patients. PLoS ONE 2015;10(10):e0140054.

Aoyagi KL, Brooks BD, Bearden S, Montenieri JA, Gage KL, Fisher MA. LPS modification promotes maintenance of Yersinia pestis in fleas. Microbiology 2015;161(Pt 3):628-38.

Shibayama J, Yuzyuk TN, Cox J, Makaju A, Miller M, Lichter J, Li H, Leavy JD, Franklin S, Zaitsev AV. Metabolic remodeling in moderate synchronous versus dyssynchronous pacing-induced heart failure: integrated metabolomics and proteomics study. PLoS One 2015;10(3):e0118974.

Kuijper EAM, Twisk JWR, Korsen T, Caanen MR, Kushnir MM, Rockwood AL, Meikle AW, Hompes PG, Wit JM, Lambalk CB. Mid-pregnancy, perinatal, and neonatal reproductive endocrinology: a prospective cohort study in twins and singleton control subjects. Fertility and Sterility 2015;104(6):1527-1534.e9.

Diaz MH, Benitez AJ, Cross KE, Hicks LA, Kutty P, Bramley AM, Chappell JD, Hymas W, Patel A, Qi C, Williams DJ, Arnold SR, Ampofo K, Self WH, Grijalva CG, Anderson EJ, McCullers JA, Pavia AT, Wunderink RG, Edwards KM, Jain S, Winchell JM. Molecular Detection and Characterization of Mycoplasma pneumoniae Among Patients Hospitalized With Community-Acquired Pneumonia in the United States. Open Forum Infectious Diseases 2015;2(3):ofv106.

Chiu RW, Lo YM, Wittwer CT. Molecular diagnostics: a revolution in progress. Clinical Chemistry 2015;61(1):1-3.

Matynia AP, Szankasi P, Shen W, Kelley TW. Molecular genetic biomarkers in myeloid malignancies. Archives of Pathology and Laboratory Medicine 2015;139(5):594-601.

Lyon E, Schrijver I, Weck KE, Ferreira-Gonzalez A, Richards CS, Palomaki GE; CAP/ACMG Biochemical and Molecular Genetics Committee. Molecular genetic testing for cystic fibrosis: laboratory performance on the College of American Pathologists external proficiency surveys. Genetics in Medicine 2015;17(3):219-25.

Salama ME, Du S, Efimova O, Heikal NM, Wendlandt E, Toydemir RM, South S, Perkins SL, Hussong JW, Zhan F. Neoplastic plasma cell aberrant antigen expression patterns and their association with genetic abnormalities. Leukemia and Lymphoma 2015;56(2):426-33.

Qi Q, Li DY, Luo HR, Guan KL, Ye K. Netrin-1 exerts oncogenic activities through enhancing Yes-associated protein stability. Proceedings of the National Academy of Sciences of the United States of America 2015;112(23):7255-60.

Lyon E, Cockerill FR 3rd, Bale SJ, Beadling C, Bry L, Hagenkord J, Kulkarni S, Press R, Palomaki GE. Next generation sequencing in clinical diagnostics: experiences of early adopters. Clinical Chemistry 2015;61(1):41-9.

Powers-Fletcher MV, Couturier MR. Non-Helicobacter pylori Helicobacter Species Associated with Human Disease: a Primer for the Clinical Microbiology Laboratory. Clinical Microbiology Newsletter 2015;37(12):93-101.

Paxton CN, Rowe LR, South ST. Observations of the genomic landscape beyond 1p19q deletions and EGFR amplification in glioma. Molecular Cytogenetics 2015;8:60.

Dittwald P, Valkenborg D, Claesen J, Rockwood AL, Gambin A. On the Fine Isotopic Distribution and Limits to Resolution in Mass Spectrometry.Journal of the American Society for Mass Spectrometry 2015;26(10):1732-45.

Krasowski MD, Savage J, Ehlers A, Maakestad J, Schmidt GA, La'ulu SL, Rasmussen NN, Strathmann FG, Genzen JR. Ordering of the Serum Angiotensin-Converting Enzyme Test in Patients Receiving Angiotensin-Converting Enzyme Inhibitor Therapy: An Avoidable but Common Error. Chest 2015;148(6):1447-53.

Sangle NA, Taylor SL, Emond MJ, Depot M, Overholt BF, Bronner MP. Overdiagnosis of high-grade dysplasia in Barrett's esophagus: a multicenter, international study. Modern Pathology 2015;28(6):758-65.

Greene DN, Grenache DG; Education Committee of the Academy of Clinical Laboratory Physicians and Scientist. Pathology Consultation on Human Chorionic Gonadotropin Testing for Pregnancy Assessment. American Journal of Clinical Pathology 2015;144(6):830-6.

McMillin GA, Wood KE, Strathmann FG, Krasowski MD. Patterns of Drugs and Drug Metabolites Observed in Meconium: What Do They Mean? Therapeutic Drug Monitoring 2015;37(5):568-80.

Staddon JH, Smock KJ, Schiffman JD, Fluchel MN, Engel ME, Weyrich AS, Campbell RA. Pegasparaginase treatment alters thrombin generation by modulating the protein C and S system in acute lymphoblastic leukaemia/lymphoma. Blood Coagul Fibrinolysis 2015;26(7):840-3.

Wyness SP, Straseski JA. Performance characteristics of six automated 25-hydroxyvitamin D assays: Mind your 3s and 2s. Clinical Biochemistry 2015;48(16-17):1089-96.

Merrigan SD, Owen WE, Straseski JA. Performance characteristics of the ARCHITECT Active-B12 (Holotranscobalamin) assay. Clinical Laboratory 2015;61(3-4):283-8.

Greene DN, Petrie MS, Pyle AL, Kamer SM, Grenache DG. Performance characteristics of the Beckman Coulter total ßhCG (5th IS) assay. Clinica Chimica Acta 2015;439:61-7.

Ray JA, Kushnir MM, Yost RA, Rockwood AL, Meikle AW. Performance enhancement in the measurement of 5 endogenous steroids by LC-MS/MS combined with differential ion mobility spectrometry. Clinica Chimica Acta 2015;438:330-336.

Chari A, Oakeson KF, Enomoto S, Jackson DG, Fisher MA, Dale C. Phenotypic characterization of Sodalis praecaptivus sp. nov., a close non-insect-associated member of the Sodalis-allied lineage of insect endosymbionts. Internation Journal of Systemic and Evolutionary Microbiology 2015;65(Pt 5):1400-5.

Day RW, Mack GK, Barker AM, Rees TQ, Jorgensen LO, Botto LD. Prevalence of variants in methylenetetrahydrofolate reductase and the severity of pulmonary vascular disease. Pediatric Cardiology 2015;36(3):524-30.

Millson A, Lewis T, Pesaran T, Salvador D, Gillespie K, Gau CL, Pont-Kingdon G, Lyon E, Bayrak-Toydemir P. Processed Pseudogene Confounding Deletion/Duplication Assays for SMAD4. The Journal of Molecular Diagnostics 2015;17(5):576-82.

Zantek ND, Hsu P, Meijer P, Plumhoff EA, Refaai MA, Smock KJ, Van Cott EM. Quality of factor XI activity testing in North American Specialized Coagulation Laboratories. International Journal of Laboratory Hematology 2015;37 Suppl 1:99-107.

De Biase I, Liu A, Yuzyuk T, Longo N, Pasquali M. Quantitative amino acid analysis by liquid chromatography-tandem mass spectrometry: implications for the diagnosis of argininosuccinic aciduria. Clinica Chimica Acta 2015;442C:73-74.

Liew M, Farley M, Andreasen J, Parker CJ, Wittwer CT. Rare event counting of CD59- red cells in human blood: A 47-month experience using PNH consensus guidelines for WBC and RBC testing in a reference lab. Cytometry Part B: Clinical Cytometry 2015;88(4):261-9.

Tran TS, Center J, Seibel M, Eisman J, Kushnir MM, Rockwood AL, Nguyen T. Relationship between Serum Testosterone and Fracture Risk in Men: A Comparison of RIA and LC-MS/MS. Clinical Chemistry 2015;61(9):1182-90.

Howie RN, Bhattacharyya M, Salama ME, Refaey ME, Isales C, Borke J, Daoudi A, Medani F, Elsalanty ME. Removal of pamidronate from bone in rats using systemic and local chelation. Archives of Oral Biology 2015;60(12):1699-1707.

Profaizer T, Coonrod EM, Delgado JC, Kumánovics A. Report on the effects of fragment size, indexing, and read length on HLA sequencing on the Illumina MiSeq. Human Immunology 2015;76(12):897-902.

Cimino PJ, Robirds DH, Tripp SR, Pfeifer JD, Abel HJ, Duncavage EJ. Retinoblastoma gene mutations detected by whole exome sequencing of Merkel cell carcinoma. Modern Pathology 2015;27(8):1073-87.

Rosolen A, Perkins SL, Pinkerton CR, Guillerman RP, Sandlund JT, Patte C, Reiter A, Cairo MS. Revised International Pediatric Non-Hodgkin Lymphoma Staging System. Journal of Clinical Oncology 2015;33(18):2112-8.

Haglock-Adler CJ, Strathmann FG. Simplified sample preparation in the simultaneous measurement of whole blood antimony, bismuth, manganese, and zinc by inductively coupled plasma mass spectrometry. Clinical Biochemistry 2015;48(3):135-9.

Büttler RM, Martens F, Kushnir MM, Ackermans MT, Blankenstein MA, Heijboer AC. Simultaneous measurement of testosterone, androstenedione and dehydroepiandrosterone (DHEA) in serum and plasma using Isotope-Dilution 2-Dimension Ultra High Performance Liquid-Chromatography Tandem Mass Spectrometry (ID-LC-MS/MS). Clinica Chimica Acta 2015;438:157-159.

Chernyshev VS, Rachamadugu R, Tseng YH, Belnap DM, Jia Y, Branch KJ, Butterfield AE, Pease LF 3rd, Bernard PS, Skliar M. Size and shape characterization of hydrated and desiccated exosomes. Analytical and Bioanalytical Chemistry 2015;407(12):3285-301.

Panarelli NC, Vaughn CP, Samowitz WS, Yantiss RK. Sporadic microsatellite instability-high colon cancers rarely display immunohistochemical evidence of Wnt signaling activation. American Journal of Surgical Pathology 2015;39(3):313-7.

Richards S, Aziz N, Bale S, Bick D, Das S, Gastier-Foster J, Grody WW, Hegde M, Lyon E, Spector E, Voelkerding K, Rehm HL; ACMG Laboratory Quality Assurance Committee. Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. Genetics in Medicine 2015;17(5):405-24.

Gibson CC, Zhu W, Davis CT, Bowman-Kirigin JA, Chan AC, Ling J, Walker AE, Goitre L, Delle Monache S, Retta SF, Shiu YT, Grossmann AH, Thomas KR, Donato AJ, Lesniewski LA, Whitehead KJ, Li DY. Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation. Circulation 2015;131(3):289-99.

Paxton CN, Rowe LR, South ST. Streamlining the OncoScan® Array Procedure for Use in a Clinical Laboratory. Journal of the Association of Genetic Technologists 2015;41(2):61-65.

Tantravahi SK, Albertson D, Agarwal AM, Ravulapati S, Poole A, Patel SB, Hawatmeh JS, Straubhar AM, Liu T, Stenehjem DD, Agarwal N. Survival Outcomes and Tumor IMP3 Expression in Patients with Sarcomatoid Metastatic Renal Cell Carcinoma. Journal of Oncology 2015;2015:181926.

Nance D, Rodgers GM. Switching haemophilia products and inhibitor risk: a United States' perspective. European Journal of Haematology 2015;94(4):283.

Sufficool KE, Lockwood CM, Able HJ, Haegemann IS, Huntington-Lopez J, Schumacher JA, Kelley TW, Duncavage E. T-cell clonality assessment by next-generation sequencing improves detection sensitivity in mycosis fungoides. Journal of the American Academy of Dermatology 2015;73(2):228-236.e2.

Zhou Z, Rawnsley DR, Goddard LM, Pan W, Cao XJ, Jakus Z, Zheng H, Yang J, Arthur JS, Whitehead KJ, Li D, Zhou B, Garcia BA, Zheng X, Kahn ML. The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression. Developmental Cell 2015;32(2):168-80.

Schrijver I, Farkas DH, Gibson JS, Lyon E; AMP Executive Committee. The Evolving Role of the Laboratory Professional in the Age of Genome Sequencing: A Vision of the Association for Molecular Pathology. The Journal of Molecular Diagnostics 2015;17(4):335-8.

Sandlund JT, Perkins SL. Uncommon non-Hodgkin lymphomas of childhood: pathological diagnosis, clinical features and treatment approaches. British Journal of Haematology 2015;169(5):631-46.

Blaschke AJ, Hersh AL, Beekmann SE, Ince D, Polgreen PM, Hanson KE. Unmet diagnostic needs in infectious disease. Diagnostic Microbiology and Infectious Diseas 2015;81(1):57-59.

Daly TM, Hill HR. Use and clinical interpretation of pneumococcal antibody measurements in the evaluation of humoral immune function. Clinical Vaccine and Immunology 2015;22(2):148-152.

McCarthy MW, Genzen JR, Wilkin TJ, Singh HK. Use of a commercial HIV co-receptor tropism assay in clinical practice. AIDS Patient Care STDS 2015;29(2):53-4.

Grenache DG. Variable accuracy of home pregnancy tests: truth in advertising? Clinical Chemistry and Laboratory Medicine 2015;53(3):339-41.

Jez S, Martin M, South S, Vanzo R, Rothwell E. Variants of unknown significance on chromosomal microarray analysis: parental perspectives. Journal of Community Genetics 2015;6(4):343-9.