Hematologic Cancer

ARUP offers a comprehensive array of over 60 tests in the area of hematopathology including flow cytometry, molecular diagnostics, immunohistochemistry, cytogenetics and fluorescence in situ hybridization (FISH). Among the molecular tests currently offered are FLT-3, NPM-1, CEBPA, WT1, MPL, JAK2 (V617F), JAK2 (exon 12), IDH1/2, KIT, PML-RARA and BCR-ABL1 kinase. In addition, quantitative PCR testing is available for PML-RARA and BCR-ABL1 (p190 and p210). Extensive FISH testing, for both fresh and fixed specimens, is available to aid in the diagnosis and prognostication of numerous myeloid and lymphoid neoplasms. An expanded menu of immunohistochemical stains is offered by ARUP with “stain and return” service. Flow cytometry services including interpretation and consultation integration are also available.
Test # Test Name Test Keywords Additional Information
2011132 Acute Myelogenous Leukemia Panel by FISH FISH AML P, Acute Myeloid Leukemia, AML, Myeloproliferative, MPD, PML-RARA, RUNX1T1-RUNX1, ETO-AML1, CBFB, MLL, RPN1/MECOM, EVI1, EGR1, D7S486, KMT2A
2010673 CALR (Calreticulin) Exon 9 Mutation Analysis by PCR
2003806 CD117 (c-Kit) by Immunohistochemistry Gastrointestinal Stromal Tumors (GIST), Lung Cancer, Breast Cancer, Melanoma, Mast Cell Disease, Germ Cell Tumor of Testes and Ovary, Brain Tumors, Myelodysplastic Syndromes, Acute Myeloid Leukemia, (AML), Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
Stain and return service only
2002298 Chromosome FISH, Interphase Oncology, Bone Marrow, Ewing Sarcoma, Neuroblastoma, Myelodysplastic, MDS, Chronic Lymphocytic Leukemia (CLL), Sarcoma, Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML), Tumor Markers, Acute Myeloid Leukemia (AML), Myeloproliferative Neoplasms (MPN), Plasma Cell Dyscrasias, Lymphoma Phenotyping, B-Cell Lymphomas Please specify which FISH probe you wish to order.
2002357 JAK2 Exon 12 Mutation Analysis by PCR Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
0051245 JAK2 Gene, V617F Mutation, Qualitative Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
0040168 JAK2 Gene, V617F Mutation, Quantitation Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
2011117 Myeloid Malignancies Mutation Panel by Next Generation Sequencing Additional Technical Information
2002360 Myeloproliferative Disorders Panel by FISH FISH MPD P, Chronic Myelogenous Leukemia (CML), Myeloproliferative Neoplasms (MPN), PDGFRα-CHIC2-FIP1L1, PDGFRa-CHIC2-FIP1L1, PDGFRβ, FGFR1, ABL1-BCR