Hematologic Cancer

ARUP offers a comprehensive array of over 60 tests in the area of hematopathology including flow cytometry, molecular diagnostics, immunohistochemistry, cytogenetics and fluorescence in situ hybridization (FISH). Among the molecular tests currently offered are FLT-3, NPM-1, CEBPA, WT1, MPL, JAK2 (V617F), JAK2 (exon 12), IDH1/2, KIT, PML-RARA and BCR-ABL1 kinase. In addition, quantitative PCR testing is available for PML-RARA and BCR-ABL1 (p190 and p210). Extensive FISH testing, for both fresh and fixed specimens, is available to aid in the diagnosis and prognostication of numerous myeloid and lymphoid neoplasms. An expanded menu of immunohistochemical stains is offered by ARUP with “stain and return” service. Flow cytometry services including interpretation and consultation integration are also available.
Test # Test Name Test Keywords Additional Information
0049010 Acid Hemolysin (Ham Test)Paroxysmal Nocturnal Hemoglobinuria (PNH) Paroxysmal Nocturnal Hemoglobinuria (PNH) PNH testing with Flaer by flow cytometry may be a better test to evaluate for PNH
2002647 Acute Lymphocytic Leukemia (ALL) Panel by FISH, Adult FISH A ALL, B-Cell Lymphoma, MYC BCR-ABL1, MLL, IGH@, TCF3, E2A
2002719 Acute Lymphocytic Leukemia (ALL) Panel by FISH, Pediatric FISH P ALL, Oncology, Bone Marrow , B-Cell Lymphoma, childhood, child, children, CEP4, CEP10, BCR-ABL1 MLL, ETV6-RUNX1, TEL-AML1
2002653 Acute Myelogenous Leukemia (AML) with Myelodysplastic Syndrome (MDS), or Therapy-Related AML, by FISH F TAML MDS, Myelodysplastic syndrome, Acute Myeloid Leukemia, EGR1, D7S486, MLL
2011132 Acute Myelogenous Leukemia Panel by FISH FISH AML P, Acute Myeloid Leukemia, AML, Myeloproliferative, MPD, PML-RARA, RUNX1T1-RUNX1, ETO-AML1, CBFB, MLL, RPN1/MECOM, EVI1, EGR1, D7S486, KMT2A
2003439 Anaplastic Lymphoma Kinase 1 (ALK-1) by Immunohistochemistry Sarcoma, T/NK-Cell Lymphomas, B-Cell Lymphomas, Tumor Markers, Non-small cell carcinoma, lung, malignant rhabdoid tumor Stain and return service only
2003442 B Cell Specific Octamer Binding Protein-1 (BOB-1) by Immunohistochemistry B-Cell Lymphomas, Tumor Markers Stain and return service only
0092099 B-Cell CD20 Expression B-cell lymphomas, B-cell leukemias
2006193 B-Cell Clonality Screening (IgH and IgK) by PCR B-Cell Lymphomas, B-cell Leukemias Additional Technical Information
2004513 BCL-2 by Immunohistochemistry Follicular lymphoma, Diffuse large B-cell lymphoma, B-Cell Lymphomas Stain and return service only
2003457 BCL-6 by Immunohistochemistry B-Cell Lymphomas, Tumor Markers Stain and return service only
2008420 BCR-ABL1 Mutation Analysis by Next Generation Sequencing Chronic Myelogenous Leukemia (CML), Acute Lymphoblastic Leukemia (ALL), Tumor Markers, NGS Additional Technical Information
2005017 BCR-ABL1, Major (p210), Quantitative Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML)
2005016 BCR-ABL1, Minor (p190), Quantitative Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML)
2005010 BCR-ABL1, Qualitative with Reflex to BCR-ABL1 Quantitative Chronic Myelogenous Leukemia (CML)
0050161 Bence Jones Protein, Qualitative Free Kappa and Lambda Light Chains, Urine Plasma cell dyscrasias
0050618 Bence Jones Protein, Quantitative Free Kappa and Lambda Light Chains, Urine Plasma cell dyscrasias
0080053 Beta-2 Microglobulin, Serum or Plasma Hematologic neoplasms
2003466 BF-1 by Immunohistochemistry T/NK-Cell Lymphomas, Tumor Markers Stain and return service only
2012222 Bone Marrow Failure Sequencing, 35 Genes BMF SEQ Bone Marrow Failure, Fanconi anemia, dyskeratosis congenita, Diamond-Blackfan anemia, Shwachman-Diamond syndrome, acute myelogenous leukemia,
2007130 Bone Marrow, Chromosome Analysis with Reflex to Genomic Microarray ALL, Bcell, B-cell, b cell, T-cell, Tcell, T Cell, B-ALL, CDKN2A/B, BTG1, IKZF1, EBF1, UPD 9p, Myelodysplastic, MDS, Myeloproliferative, MPD, 5q-; -7 or 7q-,+8; 20q-, LOH, UPD 7q, UPD 11q, UPD 17p, CLL, P53, Chronic lymphocytic leukemia
2007132 BRAF V600E Mutation Detection in Hairy Cell Leukemia by Real-Time PCR, Quantitative Additional Technical Information
2008317 C-MYC by Immunohistochemistry Stain and return service only
2010673 CALR (Calreticulin) Exon 9 Mutation Analysis by PCR
2011114 CBFB-MYH11 inv(16) Detection, Quantitative Acute Myeloid Leukemia (AML), Tumor Markers Additional Technical Information
2003523 CD10 (CALLA) by Immunohistochemistry Acute Lymphoblastic Leukemia (ALL), Follicular lymphoma, Burkitt lymphoma, Diffuse large B-cell lymphoma, B-Cell Lymphomas, Tumor Markers Stain and return service only
2003806 CD117 (c-Kit) by Immunohistochemistry Gastrointestinal Stromal Tumors (GIST), Lung Cancer, Breast Cancer, Melanoma, Mast Cell Disease, Germ Cell Tumor of Testes and Ovary, Brain Tumors, Myelodysplastic Syndromes, Acute Myeloid Leukemia, (AML), Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
Stain and return service only
2003812 CD138 (Syndecan-1) by Immunohistochemistry Plasma Cell Dyscrasias, B-Cell Lymphomas, Tumor Markers Stain and return service only
2003526 CD14 by Immunohistochemistry Acute Myelogenous Leukemia, Chronic Myelomonocytic Leukemia, Tumor Markers Stain and return service only
2003529 CD15, Leu M1 by Immunohistochemistry Hodgkin Lymphoma, Acute Myelogenous Leukemia, Mesothelioma Stain and return service only
2005114 CD19 by Immunohistochemistry Acute Lymphoblastic Leukemia, Tumor Markers, B-Cell Lymphomas Stain and return service only
2003502 CD1a by Immunohistochemistry Langerhan cell histiocytosis, T-ALL Stain and return service only
2003505 CD2 by Immunohistochemistry T-cell lymphomas, Mast Cell Disease, Sézary Syndrome, Tumor Markers Stain and return service only
2003532 CD20, L26 by Immunohistochemistry B-Cell Lymphomas, Plasma cell dyscrasias, Tumor Markers Stain and return service only
2003535 CD21 (Dendritic Cell) by Immunohistochemistry T-Cell Lymphomas, B-Cell Lymphomas, follicular dendritic cells, follicular dendritic sarcoma Stain and return service only
2003541 CD23 by Immunohistochemistry Chronic Lymphocytic Leukemia Stain and return service only
2003544 CD25 by Immunohistochemistry Mast Cell Disease, Myeloproliferative Neoplasms (MPN), Hairy cell leukemia, Sezary syndrome Stain and return service only
2003508 CD3 by Immunohistochemistry T-cell lymphomas, T-cell leukemias, Tumor Markers Stain and return service only
2003547 CD30 (Ki-1) by Immunohistochemistry Hodgkin lymphoma, T-cell lymphoma, B-Cell Lymphomas, Tumor Markers, solitary fibrous tumor, sarcoma Stain and return service only
2003553 CD33 by Immunohistochemistry Acute Myeloid Leukemia (AML), Tumor Markers Stain and return service only
2003556 CD34, QBEnd/10 by Immunohistochemistry B-ALL, T-ALL, Acute myelogenous leukemia, MDS, Tumor Markers Stain and return service only
2003511 CD4 by Immunohistochemistry Sézary Syndrome, T-Cell Lymphomas, Tumor Markers Stain and return service only
2003565 CD42b by Immunohistochemistry Acute myelogenous leukemia, megakaryocytes Stain and return service only
2003568 CD43, L60 (Leu 22) by Immunohistochemistry T/NK-Cell Lymphomas, B-Cell Lymphomas Stain and return service only
2003571 CD44 by Immunohistochemistry Stain and return service only
2003574 CD45 by Immunohistochemistry Non-Hodgkin lymphomas, Hodgkin Lymphomas, Tumor Markers Stain and return service only
2003514 CD5 by Immunohistochemistry T-Cell Lymphomas, B-Cell Lymphomas, Tumor Markers Stain and return service only
2003586 CD52 (CAMPATH-1) by Immunohistochemistry B-cell lymphomas, B-cell leukemias, T-cell leukemias Stain and return service only
2003589 CD56 (NCAM) by Immunohistochemistry Brain Tumors, Sarcoma , Rhabdomyosarcomas, T/NK-Cell Lymphomas, Plasma Cell Dyscrasias, Tumor Markers, Lung Cancer Stain and return service only
2003592 CD57 by Immunohistochemistry T/NK-Cell Lymphomas, Tumor Markers Stain and return service only
2003595 CD61 (Platelet Glycoprotein IIIA) by Immunohistochemistry Acute myelogenous leukemia, megakaryocytes Stain and return service only
2003598 CD68, KP1 by Immunohistochemistry Acute Myeloid Leukemia (AML), Monocytes, Histiocytes, Tumor Markers Stain and return service only
2003517 CD7 by Immunohistochemistry Sézary Syndrome, T/NK-Cell Lymphomas, Tumor Markers Stain and return service only
2003800 CD79A by Immunohistochemistry Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), B-Cell Lymphomas, Tumor Markers Stain and return service only
2003520 CD8 by Immunohistochemistry T-Cell Lymphomas, Tumor Markers Stain and return service only
2004247 CEBPA Mutation Detection Acute Myelogenous Leukemia (AML) Additional Technical Information
2002292 Chromosome Analysis, Bone Marrow Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, MDS, B-cell lymphomas, T-cell lymphomas
2002290 Chromosome Analysis, Leukemic Blood Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, MDS, B-cell lymphomas, T-cell lymphomas
2002289 Chromosome Analysis, Peripheral Blood CHR PB, karyotype, Down, Downs, Down's, Trisomy 21, Trisomy 18, Turner, Turner's, Turners, Klinefelter, Klinefelter's, Klinefelters, trisomy 13, mental retardation, developmental delay, 45X, 45,X, XXY, XYY, anomalies, birth defects, infertility
2002296 Chromosome Analysis, Solid Tumor CHR ST, Sarcoma, Ewings
2002295 Chromosome FISH, CLL Panel FISH CLLP, Chronic Lymphocytic Leukemia, CLL, Lymphoma Phenotyping, B-Cell Lymphomas, Tumor Markers, ATM, D12Z3, D13S319, TP53, p53
2002298 Chromosome FISH, Interphase Oncology, Bone Marrow, Ewing Sarcoma, Neuroblastoma, Myelodysplastic, MDS, Chronic Lymphocytic Leukemia (CLL), Sarcoma, Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML), Tumor Markers, Acute Myeloid Leukemia (AML), Myeloproliferative Neoplasms (MPN), Plasma Cell Dyscrasias, Lymphoma Phenotyping, B-Cell Lymphomas Please specify which FISH probe you wish to order.
2008622 CXCL13 by Immunohistochemistry Stain and return service only
2003842 Cyclin D1, SP4 by Immunohistochemistry Head and Neck Cancer, Tumor Markers, Mantle cell lymphoma, B-Cell Lymphomas Stain and return service only
2010229 Cytogenomic Molecular Inversion Probe Array, Copy Number and Heterozygosity Assessment - Formalin-Fixed Paraffin-Embedded (FFPE) Tissue FFPE ARRAY, array CGH; aCGH; Array Comparative Genomic Hybridization; Chromosomal Microarray; CMA;  CGH; Microarray; Single-nucleotide-polymorphism (SNP) array; Whole Genome Array; tumor; oncology, formalin-fixed, paraffin-embedded, FFPE; tissue
2006325 Cytogenomic SNP Microarray—Oncology CMA ONC ALL, Bcell, B-cell, b cell, T-cell, Tcell, T Cell, B-ALL, CDKN2A/B, BTG1, IKZF1, EBF1, UPD 9p, Myelodysplastic, MDS, Myeloproliferative, MPD, 5q-; -7 or 7q-,+8; 20q-, LOH, UPD 7q, UPD 11q, UPD 17p, CLL, P53, Chronic lymphocytic leukemia Additional Technical Information
2010696 EIF2AK4-Associated Disorders (EIF2AK4) Sequencing
2002378 Eosinophilia Panel by FISH FISH EOS P, Mast Cell Disease, Eosinophilic Diseases, Acute Myeloid Leukemia (AML), Myeloproliferative Neoplasms (MPN), PDGFRA-CHIC2-FIP1L1, PDGFRB, FGFR1, CBFB
0050227 Erythropietin, Serum or Plasma MPN
0049050 Esterase Stain, Nonspecific Acute Myeloid Leukemia (AML)
2005400 FLT3 Mutation Detection by PCR Acute Myeloid Leukemia Additional Technical Information
2011806 FLT3 Signal Ratio Mutation Detection by PCR Acute Myeloid Leukemia Additional Technical Information
2007173 Granzyme B by Immunohistochemistry Stain and Return service only
2003932 Herpes Virus 8 by Immunohistochemistry Kaposi Sarcoma, B-Cell Lymphomas, B- and T-Cell Markers Lymphoma, Castleman disease, Primary Effusion Lymphomas, Tumor Markers Stain and return service only
0020642 Human T-Lymphotrophic Virus Types I/II Antibodies, Western Blot HTLV leukemia/lymphoma
0051164 Human T-Lymphotropic Virus Types I/II Antibodies with Reflex to HTLV I/II Confirmation HTLV leukemia/lymphoma
2006444 IDH1 and IDH2 Mutation Analysis, exon 4 Gliomas, cytogenically normal AML cases Additional Technical Information
2001536 IGH-BCL2 Fusion, t(14;18) by FISH for Detection in Follicular Lymphoma B-Cell Lymphomas, Follicular lymphoma, Diffuse large B-cell lymphoma, FISH Additional Technical Information
0055557 IGH-CCND1 (BCL-1/JH) Translocation, t(11;14) by PCR Mantle cell Lymphoma , B-Cell Lymphomas, Tumor Markers Additional Technical Information
2007226 IGH-CCND1 Fusion, t(11;14) by FISH Mantle cell lymphoma, B-Cell Lymphomas, Plasma cell dyscrasias, Tumor Markers Additional Technical Information
2001538 IGH-MYC Fusion t(8;14) by FISH for Detection in Burkitt Lymphoma Burkitt lymphoma, B-Cell Lymphomas Additional Technical Information
0040227 IGHV Mutation Analysis by Sequencing Chronic Lymphocytic Leukemia (CLL), Lymphoma Phenotyping, B-Cell Lymphomas, Tumor Markers Additional Technical Information
0050272 Immunofixation Electrophoresis Gel B-cell lymphomas, plasma cell dyscrasias
2003975 MUM1/IRF4 by Immunohistochemistry B-Cell Lymphomas, Hodgkin lymphoma, Tumor Markers Stain and return service only
2002357 JAK2 Exon 12 Mutation Analysis by PCR Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
0051245 JAK2 Gene, V617F Mutation, Qualitative Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
2012084 JAK2 Gene, V617F Mutation, Qualitative with Reflex to CALR (Calreticulin) Exon 9 Mutation Analysis by PCR with Reflex to MPL codon 515 Mutation Detection by Pyrosequencing, Quantitative
2012085 JAK2 Gene, V617F Mutation, Qualitative with Reflex to JAK2 Exon 12 Mutation Analysis by PCR
0040168 JAK2 Gene, V617F Mutation, Quantitation Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
2003981 Kappa Light Chains by Immunohistochemistry Plasma Cell Dyscrasias, B-Cell Lymphomas, plasma cell dyscrasias Stain and return service only
0055167 Kappa/Lambda Quantitative Free Light Chains with Ratio, Serum Plasma cell dyscrasias, B-cell lymphomas
2004519 Ki-67, MIB1, by Immunohistochemistry B-cell Lymphomas, T-Cell Lymphomas, Tumor marker, astrocytoma Stain and return service only
0040137 KIT (D816V) Mutation by PCR Mast Cell Disease, C-KIT, CKIT Additional Technical Information
2002437 KIT Mutations in AML by Fragment Analysis and Sequencing Acute Myeloid Leukemia (AML), C-KIT, CKIT Additional Technical Information
2003984 Lambda Light Chains by Immunohistochemistry Plasma Cell Dyscrasias, B-Cell Lymphomas Stain and return service only
2008003 Leukemia/Lymphoma Phenotyping by Flow Cytometry Additional Technical Information
2007131 Leukemic Blood, Chromosome Analysis with Reflex to Genomic Microarray
0049000 Leukocyte Alkaline Phosphatase Chronic Myelogenous Leukemia (CML), Hematologic Cancer
2002650 Lymphoma (Aggressive) Panel by FISH FISH ALYMP, Lymphoma Phenotyping, B-Cell Lymphomas, Lymphoproliferative Disorders (LPD), BCL6, MYC, IGH@/BCL2 Additional Technical Information
0050368 Lysozyme, Urine Hematologic Cancer
2003993 Mast Cell Tryptase by Immunohistochemistry Mast Cell Disease Stain and return service only
2005545 MPL codon 515 Mutation Detection by Pyrosequencing, Quantitative Myeloproliferative Neoplasms, MPN Additional Technical Information
2002294 Multiple Myeloma Panel by FISH FISH MMP, Plasma Cell Dyscrasias, CKS1B, ASS1, CCND1-IGH@, IGH@, PML, TP53, FGFR3-IGH@, IGH@-MAF
2002345 MYC (8q24) Gene Rearrangement by FISH Burkitt lymphomas, B-Cell Lymphomas, Double Hit lymphomas, Tumor Markers Additional Technical Information
2009318 MYD88 L265P Mutation Detection by PCR, Quantitative Additional Technical Information
2002709 Myelodysplastic Syndrome (MDS) Panel by FISH FISH MDS P, Myelodysplastic Syndrome (MDS), EGR1, D7S486, CEP8, D20S108
2011117 Myeloid Malignancies Mutation Panel by Next Generation Sequencing Additional Technical Information
2012182 Myeloid Malignancies Somatic Mutation and Copy Number Analysis Panel MYE CMANGS same as CMA ONC, MYE NGS
2004014 Myeloperoxidase (MPO) by Immunohistochemistry Myelodysplastic Syndrome (MDS), Acute Myelogenous Leukemia (AML), Tumor Markers Stain and return service only
2002360 Myeloproliferative Disorders Panel by FISH FISH MPD P, Chronic Myelogenous Leukemia (CML), Myeloproliferative Neoplasms (MPN), PDGFRα-CHIC2-FIP1L1, PDGFRa-CHIC2-FIP1L1, PDGFRβ, FGFR1, ABL1-BCR
0040174 NPM1 Mutation by PCR and Fragment Analysis Acute Myeloid Leukemia (AML) Additional Technical Information
2004061 Octamer Transcription Factor-2 (Oct 2) by Immunohistochemistry B-Cell Lymphomas, Tumor Markers Stain and return service only
2004082 Pax-5 by Immunohistochemistry Acute Myelogenous Leukemia (AML), B-Cell Lymphomas, Hodgkin lymphomas, Tumor Markers Stain and return service only
2002871 PML-RARA Translocation, t(15;17) by RT-PCR, Quantitative Acute Myelogenous Leukemia (AML), Acute Promyelocytic Leukemia (APL) Additional Technical Information
2002363 PML/RARα Translocation by FISH FISH PML, Acute Myeloid Leukemia (AML), Acute Promyelocytic Leukemia (APL), Tumor Markers
2002109 Protein Electrophoresis with Reflex to Immunofixation Electrophoresis Monoclonal Protein Detection, Quantitation and Characterization, IgA, IgG, & IgM, Serum B-cell lymphomas, plasma cell dyscrasias
0050590 Protein Electrophoresis, CSF B-cell lymphomas, plasma cell dyscrasias
2008460 RBC Band 3 Protein Reduction in Hereditary Spherocytosis Additional Technical Information
2010138 RUNX1-RUNX1T1 (AML1-ETO) t(8;21) Detection, Quantitative
0049180 Sezary Cell Exam Sézary Syndrome, Mycosis Fungoides
2005984 Special Stain, Periodic Acid-Schiff (PAS)
0093199 T-Cell Clonality by Flow Cytometry Analysis of TCR V-Beta
2008409 T-Cell Clonality by Next Generation Sequencing Additional Technical Information
0055567 T-Cell Clonality Screening by PCR Hematologic Cancer, Sézary Syndrome, T-Cell Lymphomas, Lymphoma Phenotyping
2004148 T-cell Intracytoplasmic Antigen (TIA-1) by Immunohistochemistry T/NK-Cell Lymphomas, Tumor Markers Stain and return service only
2004160 Tartrate-Resistant Acid Phosphatase (TRAP) by Immunohistochemistry Hairy cell leukemia, B-Cell Lymphomas Stain and return service only
2004142 TdT by Immunohistochemistry Acute Lymphoblastic Leukemia (ALL), B-cell and T-cell Acute Lymphoblastic Leukemia, Tumor Markers Stain and return service only
0020056 Viscosity, Serum B-cell lymphomas, plasma cell dyscrasias
2005766 WT1 Mutation Detection by Sequencing AML Additional Technical Information
0092392 ZAP-70 Analysis by Flow Cytometry Chronic Lymphocytic Leukemia (CLL), Lymphoma Phenotyping, B-Cell Lymphomas, Tumor Markers Additional Technical Information