Thrombotic Thrombocytopenic Purpura

Test Code Test Name Ordering recommendations
0030056 ADAMTS13 Activity Assists in diagnosing congenital or inherited thrombotic thrombocytopenic purpura (TTP).
3000182 ADAMTS13 Antibody Assist in distinguishing between inherited and acquired forms of thrombotic thrombocytopenic purpura (TTP). Not recommended as initial test for identification of autoantibodies to ADAMTS13, since the ADAMTS13 antibody test is less specific for acquired TTP than ADAMTS13 Inhibitor (3000228). Order when acquired TTP is suspected but antibodies are not identified by the ADAMTS13 inhibitor test.
3000228 ADAMTS13 Inhibitor Assist in distinguishing between inherited and acquired forms of thrombotic thrombocytopenic purpura (TTP). Recommended initial test for the identification of autoantibodies to ADAMTS13, since the ADAMS13 inhibitor test is more specific for acquired TTP than the ADAMTS13 antibody test. If suspicion for TTP remains after a negative result, ADAMTS13 Antibody (3000182) is recommended.
3000239 ADAMTS13 Reflex Panel Reflexive panel to assist in diagnosis of thrombotic thrombocytopenic purpura (TTP) and in distinguishing between inherited and acquired forms of TTP.