Immunohistochemistry Stains

The ARUP Immunohistochemistry Laboratory performs more than 175 stains on formalin-fixed, paraffin-embedded tissues/cellblocks. These stains are used to detect the presence, abundance, and localization of specific proteins to aid in determining the direction of differentiation in neoplasms with similar morphology as well as to provide prognostic or therapeutic information, among other applications.

This lab is pathologist oriented, providing a stain and return service only, without interpretation, to our client pathologists to assist in their diagnostic studies. Most stains are returned the next day. The available stains are listed under the Stain and Return Immunohistochemistry tab. If interpretation is needed, please order a consultation.

To order a surgical pathology consultation, please use test code 2013263 Consultation, Surgical Pathology or 2013258 Consultation, Hematopathology. For more information, call (801)581-2507. Please include pertinent clinical history and surgical pathology report.

The Immunohistochemistry Laboratory has a menu of immunohistochemistry tests for which we will provide interpretation by one of our ARUP faculty pathologists. A list of these tests can be found under the Immunohistochemistry Tests tab. The ARUP Immunohistochemistry Laboratory is an NSABP-approved laboratory for the testing of breast markers.
All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Test # Test Name Test Keywords Test Description
2003475 C4D by Immunohistochemistry
  • Deposits in peritubular capillary might distinguish between Acute Humoral Rejection (AHR) and Acute Cellular Rejection (ACR).
  • AHR: deposits prominently and diffusely in the peritubular capillaries, intense staining has been seen in a widespread, uniform distribution
2003487 Calponin by Immunohistochemistry
  • Can be used to characterize the differentiation process of mammary myoepithelial cells in the developing mammary glad, investigate the nature of myoepithelial cells and to study the development of human smooth muscle cells.
  • High expression might be used as an additional marker of vascular smooth muscle cells, myopithelial cells in normal and benign human mammary gland, and certain stromal myofibroblasts.
2003550 CD31 by Immunohistochemistry Vascular neoplasms
  • Platelet-endothelial cell adhesion molecule
  • Expressed by endothelial cells
  • Glycoprotein in platelets
  • Aids in evaluating vascularization in normal and neoplastic tissue and demonstrating endothelial cellderived tumors
2003556 CD34, QBEnd/10 by Immunohistochemistry B-ALL, T-ALL, Acute myelogenous leukemia, MDS, Tumor Markers
  • Human progenitor cell antigen
  • Present in immature hematopoietic cells and vascular endothelial cells
  • Expressed by some acute myeloid leukemias, undifferentiated leukemias, and acute lymphoblastic leukemias
2003839 Collagen IV by Immunohistochemistry Alport Syndrome Renal disease, chronic kidney disease, hematuria, alport
  • Reacts with basement membranes in kidney, skin, striated and smooth muscle, spleen, lymph node, lung, placenta, and tendon
2003857 D2-40 by Immunohistochemistry Mesothelioma, Brain Tumors
  • High sensitivity and specificity for lymphatic endothelium
  • Can be used as a reliable lymphatic endothelial cell marker in the evaluation of lymphatic involvement in tumors
2003905 Glucose Transporter-1 (GLUT-1) by Immunohistochemistry
  • Involved in glucose transport across epithelial and endothelial barrier tissues
  • Stains the membrane of normal erythrocytes in various normal and neoplastic tissues
2003987 Laminin by Immunohistochemistry
  • Reacts with receptors at cell surfaces, which results in changes in behavior of cells during embryonic development and regeneration.
2004106 Procollagen I by Immunohistochemistry
  • Secreted by fibroblasts into the extracellular matrix, where it is cleaved to form collagen
  • Expression and secretion of procollagen is an important feature of wound-healing and tissue-repair processes to which the desmoplastic stroma of malignancy have sometimes been compared