Immunohistochemistry Stains

The ARUP Immunohistochemistry Laboratory performs more than 175 stains on formalin-fixed, paraffin-embedded tissues/cellblocks. These stains are used to detect the presence, abundance, and localization of specific proteins to aid in determining the direction of differentiation in neoplasms with similar morphology as well as to provide prognostic or therapeutic information, among other applications.

This lab is pathologist oriented, providing a stain and return service only, without interpretation, to our client pathologists to assist in their diagnostic studies. Most stains are returned the next day. The available stains are listed under the Stain and Return Immunohistochemistry tab. If interpretation is needed, please order a consultation.

For information concerning consultation, please call (801) 581-2507. Consultations can be sent directly to:

Surgical Pathology Department
Huntsman Cancer Hospital
1950 Circle of Hope, RM N3105
Salt Lake City, UT 84112
Phone: (801) 581-2507 or (801) 584-5078
Fax: (801) 581-7035

Please include pertinent clinical history and surgical pathology report.

The Immunohistochemistry Laboratory has a menu of immunohistochemistry tests for which we will provide interpretation by one of our ARUP faculty pathologists. A list of these tests can be found under the Immunohistochemistry Tests tab. The ARUP Immunohistochemistry Laboratory is an NSABP-approved laboratory for the testing of breast markers. Enhanced reports are available for Herceptin® testing.
All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Test # Test Name Test Keywords Test Description
2003502 CD1a by Immunohistochemistry Langerhan cell histiocytosis, T-ALL
  • Non-polymorphic MHC class I-related cell surface glycoprotein
  • Expressed by interdigitating reticulum cells, cortical thymocytes, thymomas, langerhans cells and Langerhans histiocytosis cells (histiocytosis X)
  • Aids in identifying some T-cell lymphomas and leukemias
2003598 CD68, KP1 by Immunohistochemistry Acute Myeloid Leukemia (AML), Monocytes, Histiocytes, Tumor Markers KP-1:
  • Expressed by Macrophages, blood monocytes, mast cells, and the cell population known as "plasmacytoid T-cells" in reactive lymph nodes
  • Strong to moderate staining in acute myeloid leukemia (AML), chronic myeloid leukemia (CML), true histiocytic neoplasia, melanoma, and some B-cell neoplasms (usually small lymphocytic lymphoma [SLL]) and weak staining in hairy cell leukemia
  • Weak staining in hairy cell leukemia
2013802 Langerin by Immunohistochemistry Indicated as an aid in the identification of Langerhans cells in the clinical differential diagnosis where Langerhans cell histiocytosis is suspected.
2003990 Lysozyme (Muramidase) by Immunohistochemistry Acute Myeloid Leukemia (AML)
  • Histiocytic and bacteriolytic enzyme
  • Present in granulocytes, monocytes, macrophages, histiocytes, normal hematopoietic cells, and some epithelial cells
  • Present in myeloid leukemias