Immunohistochemistry Stains

The ARUP Immunohistochemistry Laboratory performs more than 175 stains on formalin-fixed, paraffin-embedded tissues/cellblocks. These stains are used to detect the presence, abundance, and localization of specific proteins to aid in determining the direction of differentiation in neoplasms with similar morphology as well as to provide prognostic or therapeutic information, among other applications.

This lab is pathologist oriented, providing a stain and return service only, without interpretation, to our client pathologists to assist in their diagnostic studies. Most stains are returned the next day. The available stains are listed under the Stain and Return Immunohistochemistry tab. If interpretation is needed, please order a consultation.

For information concerning consultation, please call (801) 581-2507. Consultations can be sent directly to:

Surgical Pathology Department
Huntsman Cancer Hospital
1950 Circle of Hope, RM N3105
Salt Lake City, UT 84112
Phone: (801) 581-2507 or (801) 584-5078
Fax: (801) 581-7035

Please include pertinent clinical history and surgical pathology report.

The Immunohistochemistry Laboratory has a menu of immunohistochemistry tests for which we will provide interpretation by one of our ARUP faculty pathologists. A list of these tests can be found under the Immunohistochemistry Tests tab. The ARUP Immunohistochemistry Laboratory is an NSABP-approved laboratory for the testing of breast markers. Enhanced reports are available for Herceptin® testing.
All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Test # Test Name Test Keywords Test Description
2003547 CD30 (Ki-1) by Immunohistochemistry Hodgkin lymphoma, T-cell lymphoma, B-Cell Lymphomas, Tumor Markers, solitary fibrous tumor, sarcoma
  • Ki-1 positive lymphoma
  • Ber-H2
  • Expressed by activated B- and T-lymphocytes, Reed-Sternberg cells
  • Aids in identifying Hodgkin lymphoma, lymphomatoid papulosis, anaplastic large cell lymphoma, some peripheral pleomorphic T-cell lymphomas (both HTLV-1 positive and negative) including those of angioimmunoblastic type and Lennert type and embryonal carcinoma
2003920 Human Chorionic Gonadotropin (Beta-hCG) by Immunohistochemistry Trophoblastic, germ cell, lung, melanoma, gastrointestinal, ovarian, testicular cancer hCG:
  • Expressed on placental trophoblasts
  • Aids in identifying trophoblastic germ cell tumor
2003938 Human Placental Lactogen (HPL) by Immunohistochemistry Gestational Trophoblastic Disease, Products of Conception HPL:
  • Reacts with placental syncytrotrophoblastic cells
  • Identifies placental site trophoblastic tumors and exaggerated placental sites
2004058 Octamer Transcription Factor-3 and -4 (Oct 3/4) by Immunohistochemistry Testicular Cancer
  • Expressed by embryonic stem cells and germ cells.
  • Has been reported to be expressed in germ cell tumors and their metastases which exhibit features of pluripotentiality including seminoma/dysgerminoma/germinoma and embryonial carcinoma.
  • Has been proposed as a useful marker for germ cell tumors and to assist in establishing a germ cell origin for some metastatic tomors of uncertain primary origin.
2004097 Placental Alkaline Phosphatase (PLAP) by Immunohistochemistry Testicular Cancer, Brain Tumors, Tumor Markers, Ovarian Cancer PLAP:
  • Expressed by placenta
  • Present in most germ cell tumors, and breast, lung, stomach, pancreas, and ovarian carcinomas