Immunohistochemistry Stains

The ARUP Immunohistochemistry Laboratory performs more than 175 stains on formalin-fixed, paraffin-embedded tissues/cellblocks. These stains are used to detect the presence, abundance, and localization of specific proteins to aid in determining the direction of differentiation in neoplasms with similar morphology as well as to provide prognostic or therapeutic information, among other applications.

This lab is pathologist oriented, providing a stain and return service only, without interpretation, to our client pathologists to assist in their diagnostic studies. Most stains are returned the next day. The available stains are listed under the Stain and Return Immunohistochemistry tab. If interpretation is needed, please order a consultation.

To order a surgical pathology consultation, please use test code 2013263 Consultation, Surgical Pathology or 2013258 Consultation, Hematopathology. For more information, call (801)581-2507. Please include pertinent clinical history and surgical pathology report.

The Immunohistochemistry Laboratory has a menu of immunohistochemistry tests for which we will provide interpretation by one of our ARUP faculty pathologists. A list of these tests can be found under the Immunohistochemistry Tests tab. The ARUP Immunohistochemistry Laboratory is an NSABP-approved laboratory for the testing of breast markers.
All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Test # Test Name Test Keywords Test Description
2003981 Kappa Light Chains by Immunohistochemistry Plasma Cell Dyscrasias, B-Cell Lymphomas, plasma cell dyscrasias
  • Reacts with free kappa chains and those in intact immunoglobulin molecules
  • Restricted expression suggests monoclonality and neoplastic process
2003978 Keratin 903 (K903) High Molecular Weight by Immunohistochemistry Mesothelioma, Bladder Cancer, Prostate Cancer, Breast Cancer High molecular weight keratin, 34βE12:
  • Specific to prostate basal cells
  • Rules out prostatic adenocarcinoma
  • High grade PIN demonstrates K 903 staining
  • Identifies squamous cell carcinomas, urothelial carcinomas, adenocarcinomas of ductal origin (breast, pancreas), and small benign acinar lesions of the prostate
  • Aids in differentiating mesotheliomas from lung adenocarcinomas
2004519 Ki-67, MIB1, by Immunohistochemistry B-cell Lymphomas, T-Cell Lymphomas, Tumor marker, astrocytoma
  • Proliferation index indicator
  • Determines growth fraction
  • Aids in differentiating melanoma from nevus cells for sentinel node biopsy
  • Distinguishes benign and malignant adrenocortical tumors