Immunohistochemistry Stains

The ARUP Immunohistochemistry Laboratory performs more than 175 stains on formalin-fixed, paraffin-embedded tissues/cellblocks. These stains are used to detect the presence, abundance, and localization of specific proteins to aid in determining the direction of differentiation in neoplasms with similar morphology as well as to provide prognostic or therapeutic information, among other applications.

This lab is pathologist oriented, providing a stain and return service only, without interpretation, to our client pathologists to assist in their diagnostic studies. Most stains are returned the next day. The available stains are listed under the Stain and Return Immunohistochemistry tab. If interpretation is needed, please order a consultation.

To order a surgical pathology consultation, please use test code 2013263 Consultation, Surgical Pathology or 2013258 Consultation, Hematopathology. For more information, call (801)581-2507. Please include pertinent clinical history and surgical pathology report.

The Immunohistochemistry Laboratory has a menu of immunohistochemistry tests for which we will provide interpretation by one of our ARUP faculty pathologists. A list of these tests can be found under the Immunohistochemistry Tests tab. The ARUP Immunohistochemistry Laboratory is an NSABP-approved laboratory for the testing of breast markers.
All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Test # Test Name Test Keywords Test Description
2003896 Gastrin by Immunohistochemistry Gastrinoma, Pancreatic Neuroendocrine Tumors (NET), Carcinoid Tumors, Tumor Markers
  • Expressed in G-cells of the pyloric antrum
  • Aids in identifying G-cell hyperplasia and gastrin-secreting tumors
2012558 GATA3 by Immunohistochemistry
  • Breast marker
  • Can be used in a panel of antibodies for diagnosis of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility. The pattern of reactivity should be nuclear.
2003899 Glial Fibrillary Acidic Protein (GFAP) by Immunohistochemistry Gastrointestinal Stromal Tumors (GIST), Brain Tumors Glial fibrillary acidic protein:
  • Expressed in astrocytes and some CNS ependymal cells
  • Identifies astrocytomas and ependymomas
  • Many neural tumors, such as neuroblastomas, schwannomas, and extra-CNS tumors, do not stain
2003905 Glucose Transporter-1 (GLUT-1) by Immunohistochemistry
  • Involved in glucose transport across epithelial and endothelial barrier tissues
  • Stains the membrane of normal erythrocytes in various normal and neoplastic tissues
2003908 Glycophorin A by Immunohistochemistry
  • Expressed in erythroid cells
  • Identifies M6 subtype of acute myeloblastic leukemia, erythroleukemia, and erythroblasts
2011925 Glypican 3 by Immunohistochemistry
  • Useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms’ tumor
2007173 Granzyme B by Immunohistochemistry
  • Granzyme B has been found to be expressed in the neoplastic counterparts of cytolytic CTL and NK-cells, therefore, Granzyme B may be a valuable tool in the diagnosis of T-cell/NK-cell lymphomas with cytotoxic phenotypes.
  • High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin’s disease.