Neuropathology

Neuropathology provides specialized tests and consultative services for diagnosis of various neurologic disorders affecting the central and peripheral nervous system in adult and pediatric patients. This division provides a full range of clinical neuropathology consultation services, including evaluation of brain biopsies, muscle and nerve biopsies, and autopsy brain specimens. The Neuropathology Division includes board-certified neuropathologists who have vast experience and expertise in diagnostic neuropathology, including neuroncology, neuromuscular disease, neurodegenerative disease, and surgical and autopsy neuropathology. This division provides all consultative services, which can be complemented by special stains, immunohistochemistry, molecular analyses, and electron microscopic studies as indicated.

For information concerning consultation, please call (801) 581-2507. Consultations can be sent directly to:

Surgical Pathology Department
Huntsman Cancer Hospital
1950 Circle of Hope, RM N3105
Salt Lake City, UT 84112
Phone: (801) 581-2507 or (801) 584-5078
Fax: (801) 581-7035

Please include pertinent clinical history and surgical pathology report(s).
Test # Test Name Test Keywords Additional Information
Consultation, Muscle/Nerve Pathology Special Study

Dystrophin Panel performed on fresh/frozen muscle biopsies:

  • Dystrophin
  • Merosin
  • Alpha-Sarcoglycan
  • Dysferlin
  • Utrophin
  • Spectrin
  • Dystrophin Rod Domain
  • Dystrophin Amino
  • Laminin

Available upon request.
2008604 1p/19q Deletion by FISH 1p19q, Oncology, Paraffin, Brain Tumors, Tumor Additional Technical Information
2003436 Alpha-1-Fetoprotein (AFP) by Immunohistochemistry Testicular Germ Cell tumor, Ovarian Germ Cell Tumor, Brain Tumors, Tumor Markers Stain and return service only
2010757 Cancer Panel, Hereditary, Deletion/Duplication, 46 Genes CANCER DD, ALK, APC, BAP1, BMPR1A, CDH1, CDK4, CDKN1B, CDKN2A, EPCAM, FH, FLCN, MAX, MEN1, MET, MLH1, MSH2, MSH6, MUYTH, NF2, PHOX2B, PTEN, RB1, RET, SDHAF2, SDHB, SDHC, SDHD, SMAD4, SMARCB1, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, VHL, Lynch syndrome, breast cancer, multiple endocrine neoplasia, melanoma, retinoblastoma, paraganglioma, Li-Fraumeni, familial adenomatous polyposis, Peutz-Jegher, HNPCC, inherited cancer, renal cancer, GI cancer, colorectal cancer
2012032 Cancer Panel, Hereditary, Sequencing and Deletion/Duplication, 47 Genes CANCERPAN, Lynch syndrome, breast cancer, multiple endocrine neoplasia, melanoma, retinoblastoma, paraganglioma, Li-Fraumeni, familial adenomatous polyposis, Peutz-Jegher, HNPCC, inherited cancer, renal cancer, GI cancer, colorectal cancer, NGS cancer panel
2003806 CD117 (c-Kit) by Immunohistochemistry Gastrointestinal Stromal Tumors (GIST), Lung Cancer, Breast Cancer, Melanoma, Mast Cell Disease, Germ Cell Tumor of Testes and Ovary, Brain Tumors, Myelodysplastic Syndromes, Acute Myeloid Leukemia, (AML), Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
Stain and return service only
2003589 CD56 (NCAM) by Immunohistochemistry Brain Tumors, Sarcoma , Rhabdomyosarcomas, T/NK-Cell Lymphomas, Plasma Cell Dyscrasias, Tumor Markers, Lung Cancer Stain and return service only
2010188 Central Nervous System Hereditary Cancer Panel, Sequencing and Deletion/Duplication, 15 Genes CNSCAPAN, ALK, APC, BAP1, MLH1, MSH2, MSH6, NF2, PHOX2B, PTEN, RB1, SMARCB1, STK11, SUFU, TP53, and VHL, CNS cancer, brain cancer , central nervous system cancer, CNS tumor, brain tumor, glioblastoma, neuroblastoma, meningiomas, pituitary adenoma, medulloblastoma, neuroectodermal, hemangioblastoma, pinealoblastoma, ependymoma, vestibular schwannoma ALK, APC, BAP1, MLH1, MSH2, MSH6, NF2, PHOX2B, PTEN, RB1, SMARCB1, STK11, SUFU, TP53, VHL, CNS tumor, ependymoma, glioblastoma, hemangioblastoma, medulloblastoma, meningiomas, neuroectodermal, pinealoblastoma, pituitary adenoma, vestibular schwannoma
2003830 Chromogranin A by Immunohistochemistry Neuroendocrine Tumors (NET), Carcinoid Tumors, Medullary Thyroid Cancer, Tumor Markers, Paraganglioma, Carotid body tumor, Olfactory neuroblastoma, pituitary adenomas, islet cell tumors, phaeochromocytomas, medullary thyroid carcinomas, Merkel cell tumors, and carcinoids Stain and return service only
2013261 Comprehensive Nerve Biopsy Workup
2003493 Cytokeratin 8,18 Low Molecular Weight (CAM 5.2) by Immunohistochemistry Carcinoid Tumors, Hepatocellular Carcinoma, Renal Cell, Rhabdoid tumors, Neuroendocrine, Pancreatic Cancer, Pheochromocytoma, Melanoma, Tumor Markers, Multiple Carcinomas, Colon Cancer, Gastrointestinal Cancer Stain and return service only
2000623 Cytology, Non-Gynecologic
2003857 D2-40 by Immunohistochemistry Mesothelioma, Brain Tumors Stain and return service only
2008605 EGFR by FISH EGFRFISH, Head and Neck Cancer, Lung Cancer, Brain Tumors Additional Technical Information
0051033 Ganglioside (Asialo-GM1, GM1, GM2, GD1a, GD1b, and GQ1b) Antibodies
0050591 Ganglioside (GM1) Antibodies, IgG and IgM
2004998 Ganglioside (GM1, GD1b, and GQ1b) Antibodies, IgG and IgM
2003899 Glial Fibrillary Acidic Protein (GFAP) by Immunohistochemistry Gastrointestinal Stromal Tumors (GIST), Brain Tumors Stain and return service only
2003920 Human Chorionic Gonadotropin (Beta-hCG) by Immunohistochemistry Trophoblastic, germ cell, lung, melanoma, gastrointestinal, ovarian, testicular cancer Stain and return service only
2006444 IDH1 and IDH2 Mutation Analysis, exon 4 Gliomas, cytogenically normal AML cases Additional Technical Information
2007357 IDH1 R132H Point Mutation with Interpretation by Immunohistochemistry IDH1 IP Additional Technical Information
2005857 IDH1R132H Mutation by Immunohistochemistry Glial tumors, astrocytomas , oligodendrogliomas, glioblastomas Additional Technical Information
Stain and return service only
2003969 Inhibin by Immunohistochemistry Brain Tumors, Ovarian Cancer Stain and return service only
2004519 Ki-67, MIB1, by Immunohistochemistry B-cell Lymphomas, T-Cell Lymphomas, Tumor marker, astrocytoma Stain and return service only
2009310 MGMT Methylation Detection by PCR
2007967 Motor and Sensory Neuropathy Evaluation with Immunofixation Electrophoresis and Reflex to Titer and Neuronal Immunoblot
2007966 Motor and Sensory Neuropathy Evaluation with Reflex to Titer and Neuronal Immunoblot
0051225 Motor Neuropathy Panel
2007227 MYCN (N-MYC) Gene Amplification by FISH NMYC, Neuroblastoma, Tumor Markers Additional Technical Information
2004412 Myelin Associated Glycoprotein (MAG) Antibodies, IgM and Sulfate-3-Glucuronyl Paragloboside (SGPG) Antibodies, IgM
0051285 Myelin Associated Glycoprotein (MAG) Antibody, IgM
2004052 Neuron Specific Enolase, Polyclonal (NSE P) by Immunohistochemistry Neuroendocrine Marker, neuronal or neuroendocrine cells and their tumors: neuroblastomas and retinoblastomas Stain and return service only
0098198 Neuron Specific Enolase, Serum Brain Cancer, Gastrointestinal Cancer, Head and Neck Cancer, Lung Cancer, Tumor Markers, Monitoring
2004046 Neuronal Nuclei (NeuN) by Immunohistochemistry Stain and return service only
2004522 p53 by Immunohistochemistry Tumor marker, Non-small cell lung cancer, lung cancer Stain and return service only
2004097 Placental Alkaline Phosphatase (PLAP) by Immunohistochemistry Testicular Cancer, Brain Tumors, Tumor Markers, Ovarian Cancer Stain and return service only
2004127 S-100 Protein by Immunohistochemistry Melanoma, Tumor Markers Stain and return service only
2007965 Sensory Neuropathy Antibody Panel with Reflex to Titer and Neuronal Western Blot
2007991 Solid Tumor Mutation Panel by Next Generation Sequencing Additional Technical Information
0051284 Sulfate-3-Glucuronyl Paragloboside (SGPG) Antibody, IgM
2004139 Synaptophysin by Immunohistochemistry Neuroendocrine Marker, Glucagonoma, Somatostatinoma, VIPoma, Insulinoma, Ewing Sarcoma, Gastrinoma, Pancreatic Neuroendocrine Tumors (NET), Carcinoid Tumors, Brain Tumors, Pancreatic Cancer, Pheochromocytoma, Lung Cancer, Tumor Markers Stain and return service only