Hematopathology

The Hematopathology Laboratory and the Division of Hematopathology offers diagnostic consultative services and a comprehensive testing menu for the evaluation of hematologic disorders. The Division of Hematopathology consists of nationally and internationally known experts whose expertise spans many different subspecialties of hematopathology including flow cytometry, immunohistochemistry, cytogenetics, coagulation, and molecular diagnostics. An integrated approach is utilized to provide clients with services ranging from test interpretation and selection to a comprehensive histomorphologic diagnosis.

For information concerning consultation, please call (801) 581-5854. Consultations can be sent directly to:

ARUP Laboratories
Specimen Processing

500 Chipeta Way
Salt Lake City, Utah 84108

Phone: (801) 581-5854
Fax: 801-585-3831

Please include pertinent clinical history and  surgical pathology/Hematopathology and flow cytometry report(s).

Test # Test Name Test Keywords Additional Information
2013258 Consultation, Hematopathology Kidney biopsy, light microscopy, immunofluorescence, electron microscopy, Renal disease, chronic kidney disease, hematuria, Hematopathology, hematologic
0049010 Acid Hemolysin (Ham Test)Paroxysmal Nocturnal Hemoglobinuria (PNH) Paroxysmal Nocturnal Hemoglobinuria (PNH) PNH testing with Flaer by flow cytometry may be a better test to evaluate for PNH
2002647 Acute Lymphocytic Leukemia (ALL) Panel by FISH, Adult FISH A ALL, B-Cell Lymphoma, MYC BCR-ABL1, MLL, IGH@, TCF3, E2A
2002719 Acute Lymphocytic Leukemia (ALL) Panel by FISH, Pediatric FISH P ALL, Oncology, Bone Marrow , B-Cell Lymphoma, childhood, child, children, CEP4, CEP10, BCR-ABL1 MLL, ETV6-RUNX1, TEL-AML1
2002653 Acute Myelogenous Leukemia (AML) with Myelodysplastic Syndrome (MDS), or Therapy-Related AML, by FISH F TAML MDS, Myelodysplastic syndrome, Acute Myeloid Leukemia, EGR1, D7S486, MLL
2011132 Acute Myelogenous Leukemia Panel by FISH FISH AML P, Acute Myeloid Leukemia, AML, Myeloproliferative, MPD, PML-RARA, RUNX1T1-RUNX1, ETO-AML1, CBFB, MLL, RPN1/MECOM, EVI1, EGR1, D7S486, KMT2A
2012710 Aggressive B-Cell Lymphoma FISH Reflex, Tissue
0092099 B-Cell CD20 Expression B-cell lymphomas, B-cell leukemias
2006193 B-Cell Clonality Screening (IgH and IgK) by PCR B-Cell Lymphomas, B-cell Leukemias Additional Technical Information
2008420 BCR-ABL1 Mutation Analysis by Next Generation Sequencing Chronic Myelogenous Leukemia (CML), Acute Lymphoblastic Leukemia (ALL), Tumor Markers, NGS Additional Technical Information
2005017 BCR-ABL1, Major (p210), Quantitative Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML)
2005016 BCR-ABL1, Minor (p190), Quantitative Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML)
2005010 BCR-ABL1, Qualitative with Reflex to BCR-ABL1 Quantitative Chronic Myelogenous Leukemia (CML)
2012222 Bone Marrow Failure Sequencing, 35 Genes BMF SEQ Bone Marrow Failure, Fanconi anemia, dyskeratosis congenita, Diamond-Blackfan anemia, Shwachman-Diamond syndrome, acute myelogenous leukemia,
2007130 Bone Marrow, Chromosome Analysis with Reflex to Genomic Microarray ALL, Bcell, B-cell, b cell, T-cell, Tcell, T Cell, B-ALL, CDKN2A/B, BTG1, IKZF1, EBF1, UPD 9p, Myelodysplastic, MDS, Myeloproliferative, MPD, 5q-; -7 or 7q-,+8; 20q-, LOH, UPD 7q, UPD 11q, UPD 17p, CLL, P53, Chronic lymphocytic leukemia
2007132 BRAF V600E Mutation Detection in Hairy Cell Leukemia by Real-Time PCR, Quantitative Additional Technical Information
2010673 CALR (Calreticulin) Exon 9 Mutation Analysis by PCR
2011114 CBFB-MYH11 inv(16) Detection, Quantitative Acute Myeloid Leukemia (AML), Tumor Markers Additional Technical Information
2004247 CEBPA Mutation Detection Acute Myelogenous Leukemia (AML) Additional Technical Information
2002292 Chromosome Analysis, Bone Marrow Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, MDS, B-cell lymphomas, T-cell lymphomas
2002290 Chromosome Analysis, Leukemic Blood Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, MDS, B-cell lymphomas, T-cell lymphomas
2002295 Chromosome FISH, CLL Panel FISH CLLP, Chronic Lymphocytic Leukemia, CLL, Lymphoma Phenotyping, B-Cell Lymphomas, Tumor Markers, ATM, D12Z3, D13S319, TP53, p53
2002298 Chromosome FISH, Interphase Oncology, Bone Marrow, Ewing Sarcoma, Neuroblastoma, Myelodysplastic, MDS, Chronic Lymphocytic Leukemia (CLL), Sarcoma, Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML), Tumor Markers, Acute Myeloid Leukemia (AML), Myeloproliferative Neoplasms (MPN), Plasma Cell Dyscrasias, Lymphoma Phenotyping, B-Cell Lymphomas Please specify which FISH probe you wish to order.
2010229 Cytogenomic Molecular Inversion Probe Array, Copy Number and Heterozygosity Assessment - Formalin-Fixed Paraffin-Embedded (FFPE) Tissue FFPE ARRAY, array CGH; aCGH; Array Comparative Genomic Hybridization; Chromosomal Microarray; CMA;  CGH; Microarray; Single-nucleotide-polymorphism (SNP) array; Whole Genome Array; tumor; oncology, formalin-fixed, paraffin-embedded, FFPE; tissue
2006325 Cytogenomic SNP Microarray—Oncology CMA ONC ALL, Bcell, B-cell, b cell, T-cell, Tcell, T Cell, B-ALL, CDKN2A/B, BTG1, IKZF1, EBF1, UPD 9p, Myelodysplastic, MDS, Myeloproliferative, MPD, 5q-; -7 or 7q-,+8; 20q-, LOH, UPD 7q, UPD 11q, UPD 17p, CLL, P53, Chronic lymphocytic leukemia Additional Technical Information
2010696 EIF2AK4-Associated Disorders (EIF2AK4) Sequencing
2002378 Eosinophilia Panel by FISH FISH EOS P, Mast Cell Disease, Eosinophilic Diseases, Acute Myeloid Leukemia (AML), Myeloproliferative Neoplasms (MPN), PDGFRA-CHIC2-FIP1L1, PDGFRB, FGFR1, CBFB
2002902 Epstein-Barr Virus (EBV) by in situ Hybridization, Paraffin Epstein-Barr Virus (EBV), Nasopharyngeal carcinoma, NK/ T-cell lymphomas, B-cell lymphomas, Post transplant lymphoproliferative disorders, Tumor Markers, ISH, Nasopharyngeal nonkeratinizing undifferentiated carcinoma, Nasal type NK/T-cell lymphoma
0049050 Esterase Stain, Nonspecific Acute Myeloid Leukemia (AML)
2005400 FLT3 Mutation Detection by PCR Acute Myeloid Leukemia Additional Technical Information
2011806 FLT3 Signal Ratio Mutation Detection by PCR Acute Myeloid Leukemia Additional Technical Information
2002674 Gastrointestinal Stromal Tumor Mutation Gastrointestinal Stromal Tumors (GIST) Additional Technical Information
0049090 Heinz Body Stain Unstable Hemoglobinopathies, Hemolytic Anemias
2006444 IDH1 and IDH2 Mutation Analysis, exon 4 Gliomas, cytogenically normal AML cases Additional Technical Information
2001536 IGH-BCL2 Fusion, t(14;18) by FISH for Detection in Follicular Lymphoma B-Cell Lymphomas, Follicular lymphoma, Diffuse large B-cell lymphoma, FISH Additional Technical Information
0055557 IGH-CCND1 (BCL-1/JH) Translocation, t(11;14) by PCR Mantle cell Lymphoma , B-Cell Lymphomas, Tumor Markers Additional Technical Information
2007226 IGH-CCND1 Fusion, t(11;14) by FISH Mantle cell lymphoma, B-Cell Lymphomas, Plasma cell dyscrasias, Tumor Markers Additional Technical Information
2001538 IGH-MYC Fusion t(8;14) by FISH for Detection in Burkitt Lymphoma Burkitt lymphoma, B-Cell Lymphomas Additional Technical Information
0040227 IGHV Mutation Analysis by Sequencing Chronic Lymphocytic Leukemia (CLL), Lymphoma Phenotyping, B-Cell Lymphomas, Tumor Markers Additional Technical Information
0049110 Iron Stain Bone marrows, Blood smears
2002357 JAK2 Exon 12 Mutation Analysis by PCR Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
0051245 JAK2 Gene, V617F Mutation, Qualitative Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
2012084 JAK2 Gene, V617F Mutation, Qualitative with Reflex to CALR (Calreticulin) Exon 9 Mutation Analysis by PCR with Reflex to MPL codon 515 Mutation Detection by Pyrosequencing, Quantitative
2012085 JAK2 Gene, V617F Mutation, Qualitative with Reflex to JAK2 Exon 12 Mutation Analysis by PCR
0040168 JAK2 Gene, V617F Mutation, Quantitation Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
2002888 Kappa/Lambda Light Chain Panel by in situ Hybridization, Paraffin Plasma cell dyscrasias, B-cell lymphomas, ISH More ISH testing
2007182 Ki-67 with Interpretation by Immunohistochemistry
0040137 KIT (D816V) Mutation by PCR Mast Cell Disease, C-KIT, CKIT Additional Technical Information
2002437 KIT Mutations in AML by Fragment Analysis and Sequencing Acute Myeloid Leukemia (AML), C-KIT, CKIT Additional Technical Information
2002695 KIT Mutations, Melanoma Melanoma, Tumor Markers, C-KIT, CKIT Additional Technical Information
2008003 Leukemia/Lymphoma Phenotyping by Flow Cytometry Additional Technical Information
2007131 Leukemic Blood, Chromosome Analysis with Reflex to Genomic Microarray
0049000 Leukocyte Alkaline Phosphatase Chronic Myelogenous Leukemia (CML), Hematologic Cancer
2002650 Lymphoma (Aggressive) Panel by FISH FISH ALYMP, Lymphoma Phenotyping, B-Cell Lymphomas, Lymphoproliferative Disorders (LPD), BCL6, MYC, IGH@/BCL2 Additional Technical Information
0055655 Methylenetetrahydrofolate Reductase (MTHFR) 2 Mutations MTHFR PCR, Thrombophilia, methotrexate sensitivity, cardiovascular, C677T, A1298C
2005545 MPL codon 515 Mutation Detection by Pyrosequencing, Quantitative Myeloproliferative Neoplasms, MPN Additional Technical Information
2002294 Multiple Myeloma Panel by FISH FISH MMP, Plasma Cell Dyscrasias, CKS1B, ASS1, CCND1-IGH@, IGH@, PML, TP53, FGFR3-IGH@, IGH@-MAF
2002345 MYC (8q24) Gene Rearrangement by FISH Burkitt lymphomas, B-Cell Lymphomas, Double Hit lymphomas, Tumor Markers Additional Technical Information
2009318 MYD88 L265P Mutation Detection by PCR, Quantitative Additional Technical Information
2002709 Myelodysplastic Syndrome (MDS) Panel by FISH FISH MDS P, Myelodysplastic Syndrome (MDS), EGR1, D7S486, CEP8, D20S108
2011117 Myeloid Malignancies Mutation Panel by Next Generation Sequencing Additional Technical Information
2012182 Myeloid Malignancies Somatic Mutation and Copy Number Analysis Panel MYE CMANGS same as CMA ONC, MYE NGS
0049030 Myeloperoxidase Stain Acute Myeloid Leukemia (AML), congenital deficiencies
2002360 Myeloproliferative Disorders Panel by FISH FISH MPD P, Chronic Myelogenous Leukemia (CML), Myeloproliferative Neoplasms (MPN), PDGFRα-CHIC2-FIP1L1, PDGFRa-CHIC2-FIP1L1, PDGFRβ, FGFR1, ABL1-BCR
0040174 NPM1 Mutation by PCR and Fragment Analysis Acute Myeloid Leukemia (AML) Additional Technical Information
2002257 Osmotic Fragility, Erythrocyte Hemolytic Anemias
2005006 Paroxysmal Nocturnal Hemoglobinuria Panel, RBC and WBC Additional Technical Information
2004366 Paroxysmal Nocturnal Hemoglobinuria, High Sensitivity, RBC Paroxysmal Nocturnal Hemoglobinuria (PNH) Additional Technical Information
PNH testing with Flaer by flow cytometry may be a better test to evaluate for PNH
2005003 Paroxysmal Nocturnal Hemoglobinuria, WBC Additional Technical Information
2002871 PML-RARA Translocation, t(15;17) by RT-PCR, Quantitative Acute Myelogenous Leukemia (AML), Acute Promyelocytic Leukemia (APL) Additional Technical Information
2002363 PML/RARα Translocation by FISH FISH PML, Acute Myeloid Leukemia (AML), Acute Promyelocytic Leukemia (APL), Tumor Markers
2008460 RBC Band 3 Protein Reduction in Hereditary Spherocytosis Additional Technical Information
2010138 RUNX1-RUNX1T1 (AML1-ETO) t(8;21) Detection, Quantitative
2006948 SDHB with Interpretation by Immunohistochemistry
0049180 Sezary Cell Exam Sézary Syndrome, Mycosis Fungoides
2005984 Special Stain, Periodic Acid-Schiff (PAS)
0093199 T-Cell Clonality by Flow Cytometry Analysis of TCR V-Beta
2008409 T-Cell Clonality by Next Generation Sequencing Additional Technical Information
0055567 T-Cell Clonality Screening by PCR Hematologic Cancer, Sézary Syndrome, T-Cell Lymphomas, Lymphoma Phenotyping
0049060 Tartrate Resistant Acid Phosphatase Stain Hairy cell leukemia
2005766 WT1 Mutation Detection by Sequencing AML Additional Technical Information
0092392 ZAP-70 Analysis by Flow Cytometry Chronic Lymphocytic Leukemia (CLL), Lymphoma Phenotyping, B-Cell Lymphomas, Tumor Markers Additional Technical Information