Anatomic Pathology Publications

Breast Publications

  1. Layfield LJ, Lewis C. In-situ and invasive components of mammary adenocarcinoma: comparison of Her-2/neu status. Anal Quant Cytol Histol. 2007 Aug; 29(4):239-243.
  2. Layfield LJ, Willmore-Payne C, Isom G, Holden JA. Monoplex lightcycler polymerase chain reaction quantitation of the HER2 gene for quality assurance of HER2/neu testing by immunohistochemistry and fluorescence in-situ hybridization. Analy Quant Cytol and Histol. 2008 Dec;16(6):562-567.
  3. Layfield LJ, Schmidt RL. HER2/neu Gene Amplification Heterogeneity: The Significance of Cells With a 3:1 HER/CEP17 Ratio. Appl Immunohistochem Mol Morphol. 2012 (in press).

Head & Neck Publications

  1. Layfield L. Fine-needle aspiration in the diagnosis of head and neck lesions: a review and discussion of problems in differential diagnosis. Diagn Cytopathol 2007; 35:798-805.
  2. Layfield LJ, Cibas ES, Gharib H, Mandel SJ. Thyroid Aspiration Cytology: Current Status. CA. 2009 Mar/Apr; 59(2):99-110.
  3. Layfield LJ, Morton MJ, Cramer HM, Hirschowitz S. Implications of the Proposed Thyroid FNA Category of “Follicular Lesion of Undetermined Significance”, (FLUS): A Five Year Multi-Institutional Analysis. Diagn Cytopathol. 2009 Oct;37(10):710-714.
  4. Wallander M, Layfield LJ, Jarboe E, Emerson L, Liu T, Thaker H, Holden J, Tripp, S. Follicular Variant of Papillary Carcinoma: Reproducibility of Histologic Diagnosis and Utility of HBME-1 Immunohistochemistry and BRAF Mutational Analysis as Diagnostic Adjuncts. Appl Immunohistochem Mol Morphol. 2010 May;18(3):231-235.
  5. Layfield LJ, Cibas ES, Baloch Z. Thyroid fine needle aspiration cytology: a review of the National Cancer Institute state of the science symposium. Cytopathology. 2010 Apr;21(2):75-85.
  6. Jarboe EA, Hunt JP, Layfield LJ. Cytomorphologic Diagnosis and HPV Testing of Metastatic and Primary Oropharyngeal Squamous Cell Carcinomas: A Review and Summary of the Literature. Diagnostic Cytopathology. 2011 (in press).
  7. Schmidt RL, Factor RE, Hall BJ, Wilson AR, Layfield LJ. Fine-needle Aspiration Cytology versus Core Needle Biopsy for Major Salivary Gland Lesions (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 2, Art No.: CD009610. DOI: 10.1002/14651858.CD009610.
  8. Williams SB, Ellis GE, Warnock GR. Sialoblastoma: a clinicopathologic and immunohistochemical study of 7 cases. Ann Diagn Pathol 2006; 10:320-6.
  9. Ellis GL. Lymphoid lesions of salivary glands: Malignant and Benign. Med Oral Patol Oral Cir Bucal. 2007; 12[7]: E479-E485.
  10. Hewitt KM, Ellis G, Wiggins R, Bentz BG. Parosteal osteosarcoma: Case report and review of the literature. Head Neck. 2008;30(1):122-6.
  11. Ellis GL. What’s new in the AFIP fascicle on salivary gland tumors: A few highlights from the 4th series Atlas. Head Neck Pathol. 2009;3:225-230.
  12. Yakirevich E, Sabo E, Klorin G, Alos L, Cardesa A, Ellis GL, Shumway BS, Gnepp DR. Primary mucin-producing tumours of the salivary glands: a clinicopathological and morphometric study. Histopathology. 2010 Sep;57(3):395-409.
  13. Jarboe EA, Willis M, Bentz B, Buchmann L, Hunt J, Ellis G, Layfield L. Detection of human papillomavirus using hybrid capture 2 in oral brushings from patients with oropharyngeal squamous cell carcinoma. Am J Clin Pathol. 2011;135(5):766-9.
  14. Ellis GL. Diagnostic Approach to Lymphoid Lesions of Major Salivary Glands. Diagn Histopathol. Submitted.

Gastrointestinal Publications

  1. Layfield LJ, Bentz J. Giant-cell containing neoplasms of the pancreas: an aspiration cytology study. Diagn Cytopathol. 2008 Apr; 36(4)238-244.
  2. Chadwick B, Willmore-Payne C, Tripp S, Layfield LJ, Hirschowitz S, Holden J. Histologic, Immunohistochemical and Molecular Classifications of 52 IPMNs of the Pancreas. Applied Immunohistochemistry & Molecular Morphology. 2009 Jan;17(1):31-39.
  3. Layfield LJ, Jarboe EA. Cytopathology of the Pancreas: Neoplastic and Non-Neoplastic Entities. Ann Diagn Pathol. 2010; 14(2):140-151.
  4. Jarboe EA, Layfield LJ. Cytologic Features of Pancreatic Intraepithelial Neoplasia and Pancreatitis: Potential Pitfalls in the Diagnosis of Pancreatic Ductal Carcinoma. Diagn Cytopathol. 2010 Aug 20. [Epub ahead of print]
  5. Holden JA, Wilmore-Payne C, Layfield LJ. Gastrointestinal Stromal Tumors: A Guide to the Diagnosis. Surgical Pathology Clinics. 2010 Jun; 3(2):241-276.
  6. Wallander ML, Willmore-Payne C, Layfield LJ. C-KIT and PDGFRA Zygosity in Gastrointestinal Stromal Tumors: Correlation with Tumor Site, Tumor Size, Exon and CD117 Immunohistochemistry. Applied Immunohistochemistry and Molecular Morphology. 2011 Jan;19(1):21-27.
  7. Layfield LJ, Hirschowitz SL, Adler DG. Metastatic Disease to the Pancreas Documented by Endoscopic Ultrasound Guided Fine-Needle Aspiration: A Seven Year Experience. Diagnostic Cytopathology. Diagnostic Cytopathology. 2010 Diagn Cytopathol. 2010 Nov 2. [Epub ahead of print].
  8. Layfield LJ, Wallander ML. Diagnosis of Gastrointestinal Stromal Tumors from Minute Specimens: Cytomorphology, Immunohistochemistry and Molecular Diagnostic Findings. Diagnostic Cytopathology. 2011 (in press).

Lung Publications

  1. Wallander ML, Geiersbach KB, Tripp SR, Layfield LJ. Comparison of RT-PCR, Immunohistochemistry and Fluorescence in situ Hybridization Methodologies for Detection of EML4-ALK Fusion Positive Non-Small Cell Lung Carcinoma: Implications for Optimal Clinical Testing. Archives of Pathology and Laboratory Medicine. 2011 (in press).

Melanoma Publications

  1. Wallander ML, Layfield LJ, Emerson LL, Mamalis N, Davis D, Tripp S, Holden JA. KIT Mutations in Ocular Melanoma: Frequency and Anatomic Distribution. Modern Pathology. 2011 Apr 8. [Epub ahead of print]

Sarcoma Publications

  1. Layfield LJ. Cytologic Diagnosis of Osseous Lesions: A Review with Emphasis on the Diagnosis of Primary Neoplasms of Bone. 2009 Apr;37(4):299-310.
  2. Layfield LJ, Dodd LG, Hirschowitz S, Crabtree SN. Fine-Needle Aspiration of Primary Osseous Lesions: A Cost Effectiveness Study. Diagn Cytopathol. 2010 Apr;38(4):239-243.
  3. Layfield LJ. Inflammatory Myxohyaline Tumor of Distal Extremities: Cytologic Findings in a Lesion Simulating Hodgkin’s Disease or a High-Grade Myxoid Sarcoma. Diagnostic Cytopathology. 2011 Apr 15. doi: 10.1002/dc.21689. [Epub ahead of print]
  4. Wallander ML, Tripp S, Layfield LJ. MDM2 Amplification in Malignant Peripheral Nerve Sheath Tumors Correlates with p53 Protein Expression. Arch Pathol Lab Med. 2012 Jan;136(1):95-99.
  5. Hall BJ, Grossmann AH, Webber NP, Ward R, Tripp SR, Rosenthal H, Cockerell CJ, Randall, RL, Florell SJ, Layfield LJ, Liu T. Primary Cutaneous Leiomyosarcoma: A case series demonstrating morphologic diversity and immunohistochemical utility. Am J of Surg Pathol. 2011 (in press).