There are multiple methods of drug screening: rapid point-of-care cup, lab immunoassays, and high-resolution screen by time-of-flight (TOF) mass spectrometry. The cutoff values for each drug in each of the screens are listed in the table below. Urine screens include sample validity testing by creatinine.
|
ARUP Drug Screen Cup Kit #49204 Cups only #48915 |
High-Resolution Hybrid Screen (TOF) 2007479 |
Drug Screen 9 panel 0090453 9A panel 0090454 |
Drug Screen 9 panel - positive screen reflexes to confirmation 0092420 |
Drug Panel by TOF High-Resolution Screen 2003254 |
|
|---|---|---|---|---|---|
| Specimen Type | Urine | Urine | Urine | Serum/Plasma | Serum/Plasma |
| Methodology | Point-of-care IA | LC-TOF, IA | IA, Enz | IA | LC-TOF |
| Turn-around time of screen | 5 min | 1–3 days | 1–2 days | 1–4 days | 1–4 days |
Drug / Drug Class: Screen Cutoff Values |
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| Amphetamine (AMP) | 1000 ng/mL | 100 ng/mL | 300 ng/mL | 30 ng/mL | 20 ng/mL |
| Barbiturates | 300 ng/mL | 200 ng/mL | 200 ng/mL | 75 ng/mL | 75-500 ng/mL |
| Benzodiazepines | 300 ng/mL | 20-60 ng/mL | 200 ng/mL | 75 ng/mL | 25-75 ng/mL |
| Buprenorphine | 5 ng/mL | 5 ng/mL | |||
| Cocaine | 300 ng/mL | 150 ng/mL | 150 ng/mL | 30 ng/mL | 20 ng/mL |
| Codeine | included in OPI | 40 ng/mL | Included in OPI | Included in OPI | 10 ng/mL |
| Fentanyl | 2 ng/mL | 1 ng/mL | |||
| Hydrocodone | included in OPI | 40 ng/mL | Included in OPI | Included in OPI | 10 ng/mL |
| Marijuana (THC) | 50 ng/mL | 20 ng/mL | 20 ng/mL | 30 ng/mL | 60 ng/mL |
| MDMA (ecstasy) | 500 ng/mL | 200 ng/mL | 500 ng/mL | Included in Methamphetamine | 20 ng/mL |
| Meperidine | 50 ng/mL | 5 ng/mL | |||
| Methadone | 300 ng/mL | 150 ng/mL | 150 ng/mL | 40 ng/mL | 25 ng/mL |
| Methamphetamine | 1000 ng/mL | 400 ng/mL | Included in AMP | 30 ng/mL | 20 ng/mL |
| Morphine | Included in OPI | 20 ng/mL | Included in OPI | Included in OPI | 10 ng/mL |
| Opiates Total (OPI) | 300 ng/mL | N/A | 300 ng/mL | 30 ng/mL | N/A |
| Oxycodone | 100 ng/mL | 40 ng/mL | 100 ng/mL | 30 ng/mL | 10 ng/mL |
| Phencyclidine | 25 ng/mL | 25 ng/mL | 25 ng/mL | 15 ng/mL | 10 ng/mL |
| Propoxyphene | 300 ng/mL | 25 ng/mL | 75 ng/mL | 25 ng/mL | |
| Tapentadol | 100 ng/mL | 5 ng/mL | |||
| Tramadol | 200 ng/mL | 5 ng/mL | |||
| Other analytes detected |
Tricyclic antidepressants 1000 ng/mL |
Carisoprodol 100 ng/mL EtG 500 ng/mL Phentermine 100 ng/mL Ritalinic acid 100 ng/mL Zolpidem 20 ng/mL |
[9A] Ethanol 40 mg/dL | + 20 other analytes | |
Option to Reflex to Quantitative Confirmation [see cutoffs of confirmation] |
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| Availability of automatic confirmation | No | No confirmation required unless unexpected or for quantitation. Call ASAP if confirmation is desired. |
Yes, for 9 panel 0092186;
for 9A (alcohol) panel 0092187 |
Yes, 0092420 |
No confirmation required unless for quantification. Call ASAP if confirmation is desired. |
| When the “Reflex to Quantitative Confirmation” option is ordered, we will automatically retest the specimen by mass spectrometry for the drug(s) found positive in the screen. Note that confirmation testing will not occur if the screen is negative. If you know, or suspect the patient is taking a specific drug, and wish to have the drug tested quantitatively even if the screen is negative, please order together (1) the “Reflex to Quantitative Confirmation” option for the screen AND (2) the quantitative test for the specific drug. If the screen is positive for that drug, we will automatically cancel the duplicated test. | |||||
Immunoassay:IA; Enzymatic:Enz; Ethyl glucuronide: EtG; Gas chromatography:GC; Liquid chromatography:LC; Mass spectrometry: MS; Tandem mass spectrometry:MS/MS; Time-of-flight mass spectrometry:TOF