Cutoff Values for Quantitative Confirmation after a Screen

When the Reflex to Quantitative Confirmation option is ordered, we will automatically retest the specimen by mass spectrometry for the drug(s) found positive in the screen. Note that confirmation testing will not occur if the screen is negative. If you know or suspect that the patient is taking a specific drug and wish to have the drug tested quantitatively even if the screen is negative, please order the Reflex to Quantitative Confirmation option for the screen AND the quantitative test for the specific drug. If the screen is positive for that drug, we will automatically cancel the duplicated test.

When the Reflex to Quantitative Confirmation tests are ordered, we will automatically retest the specimen by mass spectrometry (GC-MS or LC-MS/MS) for the drug(s) found positive in the screen. Note that confirmation testing will not occur if the screen is negative. Below are the cutoff values used in the confirmation.

  Reflex to Confirmation: Drug Screen 9 panel 0092186;
and 9A (Alcohol) panel 0092187
Reflex to Confirmation: Drug Screen 9 panel 0092420 Reflex to Confirmation: Drug Panel by TOF 2005444
Specimen Type urine serum/plasma serum/plasma

Drug/Drug Class: Quantitative Cutoff Values

Amphetamine (AMP) 200 ng/mL 20 ng/mL 20 ng/mL
Barbiturates 50 ng/mL 50 ng/mL 50 ng/mL
Benzodiazepines 20 ng/mL 20 ng/mL 20 ng/mL
Buprenorphine Not analyzed Not analyzed 2 ng/mL
Cocaine 50 ng/mL 20 ng/mL 20 ng/mL
Codeine 5 ng/mL 2 ng/mL 2 ng/mL
Fentanyl Not analyzed Not analyzed 0.1 ng/mL
Hydrocodone 5 ng/mL 2 ng/mL 2 ng/mL
Marijuana (THC) 5 ng/mL 5 ng/mL 5 ng/mL
MDMA (ecstasy) 200 ng/mL 5 ng/mL 5 ng/mL
Meperidine Not analyzed Not analyzed 2 ng/mL
Methadone (& metabolite) 10 ng/mL 10 ng/mL 10 ng/mL
Opiates 5 ng/mL 2 ng/mL 2 ng/mL
Oxycodone 5 ng/mL 2 ng/mL 2 ng/mL
Phencyclidine 10 ng/mL 10 ng/mL 10 ng/mL
Propoxyphene (& metabolite) 10 ng/mL 10 ng/mL 10 ng/mL
Tapentadol Not analyzed Not analyzed 2 ng/mL
Tramadol Not analyzed Not analyzed 20 ng/mL
Tricyclic antidepressants Not analyzed Not analyzed Not analyzed
Ethanol 40 mg/dL [9A only] Not analyzed Not analyzed