Sarcoma

ARUP’s test menu includes various tests to detect chromosomal rearrangements that are characteristic of specific types of sarcomas. For synovial sarcoma, ARUP offers a FISH-based test for the rearrangement of SS18 (SYT) for diagnosis, in addition to the PCR-based test for subtyping of the SYT-SSX t(X;18). For Ewing sarcoma, the lab offers an immunohistochemistry test for CD99, as well as a FISH-based for EWSR (22q12) rearrangement and a PCR-based test for the discrimination of the Type 1 and Type 2 forms of the EWS-FLI1 translocations.
Test # Test Name Test Keywords Additional Information
2003439 Anaplastic Lymphoma Kinase 1 (ALK-1) by Immunohistochemistry Sarcoma, T/NK-Cell Lymphomas, B-Cell Lymphomas, Tumor Markers, Non-small cell carcinoma, lung, malignant rhabdoid tumor Stain and return service only
2003806 CD117 (c-Kit) by Immunohistochemistry Gastrointestinal Stromal Tumors (GIST), Lung Cancer, Breast Cancer, Melanoma, Mast Cell Disease, Germ Cell Tumor of Testes and Ovary, Brain Tumors, Myelodysplastic Syndromes, Acute Myeloid Leukemia, (AML), Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
Stain and return service only
2003812 CD138 (Syndecan-1) by Immunohistochemistry Plasma Cell Dyscrasias, B-Cell Lymphomas, Tumor Markers Stain and return service only
2003535 CD21 (Dendritic Cell) by Immunohistochemistry T-Cell Lymphomas, B-Cell Lymphomas, follicular dendritic cells, follicular dendritic sarcoma Stain and return service only
2003547 CD30 (Ki-1) by Immunohistochemistry Hodgkin lymphoma, T-cell lymphoma, B-Cell Lymphomas, Tumor Markers, solitary fibrous tumor, sarcoma Stain and return service only
2003556 CD34, QBEnd/10 by Immunohistochemistry B-ALL, T-ALL, Acute myelogenous leukemia, MDS, Tumor Markers Stain and return service only
2003559 CD35 by Immunohistochemistry Sarcoma Stain and return service only
2003589 CD56 (NCAM) by Immunohistochemistry Brain Tumors, Sarcoma , Rhabdomyosarcomas, T/NK-Cell Lymphomas, Plasma Cell Dyscrasias, Tumor Markers, Lung Cancer Stain and return service only
2005534 CDK4 by Immunohistochemistry Sarcoma, liposarcoma Stain and return service only
2002296 Chromosome Analysis, Solid Tumor CHR ST, Sarcoma, Ewings
2002298 Chromosome FISH, Interphase Oncology, Bone Marrow, Ewing Sarcoma, Neuroblastoma, Myelodysplastic, MDS, Chronic Lymphocytic Leukemia (CLL), Sarcoma, Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML), Tumor Markers, Acute Myeloid Leukemia (AML), Myeloproliferative Neoplasms (MPN), Plasma Cell Dyscrasias, Lymphoma Phenotyping, B-Cell Lymphomas Please specify which FISH probe you wish to order.
2010229 Cytogenomic Molecular Inversion Probe Array, Copy Number and Heterozygosity Assessment - Formalin-Fixed Paraffin-Embedded (FFPE) Tissue FFPE ARRAY, array CGH; aCGH; Array Comparative Genomic Hybridization; Chromosomal Microarray; CMA;  CGH; Microarray; Single-nucleotide-polymorphism (SNP) array; Whole Genome Array; tumor; oncology, formalin-fixed, paraffin-embedded, FFPE; tissue
0050165 Cytomegalovirus Antibody, IgG, Serum Sarcoma
2007223 DDIT3 (CHOP) (12q13) Gene Rearrangement by FISH CHOPFISH, Sarcoma, myxoid liposarcoma, round cell liposarcoma Additional Technical Information
2003863 Desmin by Immunohistochemistry Smooth Muscle, Reactive Mesothelial cells, leiomyosarcomas, myogenic sarcomas, rhabdomyosarcoma, PNET, neuroblastoma, GIST, gastrointestinal stromal tumor, Tumor Markers Stain and return service only
2003872 Epithelial Membrane Antigen (EMA) by Immunohistochemistry Adenocarcinoma, anaplastic large cell lymphomas, epitheloid sarcomas, Pagets’ disease, plasmacytomas, Pancreatic tumors, Tumor Markers Stain and return service only
2004055 Ewing Sarcoma (O13) by Immunohistochemistry Ewing Sarcoma, Sarcoma, PNET Stain and return service only
2007225 EWSR1 (22q12) Gene Rearrangement by FISH EWSR1, Ewing Sarcoma, Sarcoma, Tumor Markers Additional Technical Information
2001497 FOXO1 (FKHR) (13q14) Gene Rearrangement by FISH FKHRFISH, Sarcoma, FOX, FOXO1, 13q14, alveolar rhabdomyosarcoma Additional Technical Information
2003887 Friend Leukemia Integration-1 (Fli-1) by Immunohistochemistry Ewing Sarcoma, Sarcoma Stain and return service only
2002674 Gastrointestinal Stromal Tumor Mutation Gastrointestinal Stromal Tumors (GIST) Additional Technical Information
2003932 Herpes Virus 8 by Immunohistochemistry Kaposi Sarcoma, B-Cell Lymphomas, B- and T-Cell Markers Lymphoma, Castleman disease, Primary Effusion Lymphomas, Tumor Markers Stain and return service only
2003448 INI1 (BAF47) by Immunohistochemistry Head and Neck Cancer, Sarcoma Stain and return service only
2005848 MDM2 by Immunohistochemistry Sarcoma, tumor marker Stain and return service only
2003016 MDM2 Gene Amplification by FISH MDM2 FISH, Sarcoma, Tumor Markers, MDM2, Murine Double Minute 2 Additional Technical Information
2004011 Muscle-Specific Actin (MSA) by Immunohistochemistry Sarcoma, leiomyomas, leiomyosarcomas, rhabdomyosarcomas, some pleomorphic liposarcomas, glomus tumors, desmoid tumors Stain and return service only
2004017 Myogenin (Myf4) by Immunohistochemistry Sarcoma, Tumor Markers, leiomyosarcomas, rhabdomyosarcomas Stain and return service only
2004031 Myoglobin by Immunohistochemistry Sarcoma, Tumor Markers, rhabdomyosarcomas Stain and return service only
2004034 Myosin by Immunohistochemistry Sarcoma, Tumor Markers, rhabdomyosarcomas Stain and return service only
2004052 Neuron Specific Enolase, Polyclonal (NSE P) by Immunohistochemistry Neuroendocrine Marker, neuronal or neuroendocrine cells and their tumors: neuroblastomas and retinoblastomas Stain and return service only
2004091 Protein Gene Product (PGP) 9.5 by Immunohistochemistry Glucagonoma, Somatostatinoma, VIPoma, Ewing Sarcoma, Gastrinoma, Pancreatic Neuroendocrine Tumors (NET), Carcinoid Tumors, Pancreatic Cancer, Pheochromocytoma, Tumor Markers, neuronal neoplasis Stain and return service only
2004130 Smooth Muscle Actin (SMA) by Immunohistochemistry Smooth Muscle Marker Stain and return service only
2007222 SS18 (SYT) (18q11) Gene Rearrangement by FISH Additional Technical Information
2004139 Synaptophysin by Immunohistochemistry Neuroendocrine Marker, Glucagonoma, Somatostatinoma, VIPoma, Insulinoma, Ewing Sarcoma, Gastrinoma, Pancreatic Neuroendocrine Tumors (NET), Carcinoid Tumors, Brain Tumors, Pancreatic Cancer, Pheochromocytoma, Lung Cancer, Tumor Markers Stain and return service only
2004166 Thyroid Transcription Factor (TTF-1) by Immunohistochemistry Thyroid Cancer, Lung Cancer, Tumor Markers, sarcoma, mesothelioma, neuroendrocrine Stain and return service only
2004172 Ulex Europaeus Agglutinin 1 (UEA-1) by Immunohistochemistry Sarcoma, angiosarcoma Stain and return service only
2004181 Vimentin by Immunohistochemistry Melanoma, Ovarian Cancer, Sarcoma, schwannoma, Endometrial Cancer, mesothelioma Stain and return service only
2004184 Wilms Tumor (WT1), N-terminus by Immunohistochemistry AML, Mesothelioma, Ovarian Cancer, desmoplastic round-cell tumor Stain and return service only