Sarcoma

ARUP’s test menu includes various tests to detect chromosomal rearrangements that are characteristic of specific types of sarcomas. For synovial sarcoma, ARUP offers a FISH-based test for the rearrangement of SS18 (SYT) for diagnosis, in addition to the PCR-based test for subtyping of the SYT-SSX t(X;18). For Ewing sarcoma, the lab offers an immunohistochemistry test for CD99, as well as a FISH-based for EWSR (22q12) rearrangement and a PCR-based test for the discrimination of the Type 1 and Type 2 forms of the EWS-FLI1 translocations.
  • Medical Director, Molecular Oncology
    Dr. Bernard is an associate professor of anatomic pathology at the University of Utah School of Medicine. He received his MD from and completed his postdoctoral training at the University of Utah and is certified in clinical pathology by the American Board of Pathology. Dr. Bernard’s laboratory at the Huntsman Cancer Center utilizes comprehensive genomic analyses to identify and translate biomarkers into clinical care for cancer patients. His work in gene expression classification of breast cancer led to the development of PAM50 (Prosigna), an FDA-approved diagnostic offered worldwide. His current research interests include using circulating cancer biomarkers for monitoring and early detection, as well as translating newly discovered cancer alterations to large nucleic acid-based panels for personalized treatment in advanced disease.
  • Co-Division Chief, Anatomic and Molecular Oncologic Pathology
    Medical Director, Biocomputing
    Dr. Bronner is a Carl R. Kjeldsberg presidential endowed professor of pathology at the University of Utah School of Medicine. Dr. Bronner received her MD from the University of Pennsylvania and completed her pathology residency training and chief residency at the Hospital of the University of Pennsylvania in Philadelphia. Dr. Bronner’s honors include her election as president of the GI Pathology Society, election as council member of the United States and Canadian Academy of Pathology, and, in 2005, the award of the Arthur Purdy Stout Prize, recognizing her work as a surgical pathologist under the age of 45 whose research publications have had a major impact on diagnostic pathology. Dr. Bronner is an editorial journal board member for Human Pathology and Modern Pathology. She has served as an investigator on numerous NIH and foundation grants over the course of her career and has published more than 100 peer-reviewed articles and numerous book chapters.
  • Director, Surgical Pathology
    Dr. Liu is an assistant professor of surgical pathology at the University of Utah School of Medicine and the program director of the surgical pathology fellowship program at the University of Utah Department of Pathology. Dr. Liu received her MD from Beijing University of Chinese Medicine and her MS in pathophysiology from Peking Union Medical College. She completed AP/CP residency training at Drexel University College of Medicine, a fellowship in hematology at Drexel University College of Medicine, and an oncologic/surgical fellowship at Memorial Sloan-Kettering Cancer Center. Dr. Liu is an AP/CP and hematopathology-boarded pathologist. Her current research interests include oncologic clinical research.
  • Medical Director, Solid Tumor Molecular Diagnostics and Histology
    Staff Pathologist, Anatomic Pathology
    Dr. Samowitz is a professor of pathology at the University of Utah School of Medicine. He received his MD from SUNY Downstate, and completed residency training in anatomic pathology at the University of Chicago and fellowships in gastrointestinal pathology at Johns Hopkins Hospital. Specializing in gastrointestinal pathology and the molecular genetics of colorectal cancer, Dr. Samowitz is also the medical director for numerous molecular tests in solid tumor molecular diagnostics, including single-gene assays and next-generation sequencing panels.