Pharmacogenetics

ARUP offers an extensive pharmacogenetic test menu to help the clinician in identifying appropriate treatment and to monitor efficacy and toxicity by evaluating the genetic differences in metabolic pathways for each individual.
  • Medical Director, Molecular Hematopathology
    Medical Director, Hematopathology
    Dr. Kelley is an associate professor in the Department of Pathology at the University of Utah. He received his MS in immunology and microbiology and his MD from Ohio State University, and completed his residency in anatomic and clinical pathology and fellowship training in hematopathology at the Cleveland Clinic. He is board certified in anatomic and clinical pathology by the American Board of Pathology, with subspecialty certification in hematology. His research interests include the identification of novel diagnostic and prognostic biomarkers in leukemia and lymphoma.
  • Medical Director, Molecular Genetics and Genomics
    Medical Director, Pharmacogenomics
    Dr. Lyon is a professor of pathology at the University of Utah School of Medicine. She received her PhD in medical genetics from the University of Alabama at Birmingham and completed an ABMG fellowship in clinical molecular genetics at the University of Utah. Dr. Lyon’s responsibilities include validating methods for mutation detection under CLIA requirements, implementing them into clinical testing, and interpreting genetic/genomic results in a clinical context. She participated in the ACMG/AMP/CAP Standards and Guidelines for the Interpretation of Sequence Variants and served as president of the Association for Molecular Pathology in 2014.
  • Section Chief, Molecular Genetics and Genomics
    Dr. Mao is a professor of pathology and co-director of the Clinical Molecular Genetics Fellowship Program at the University of Utah School of Medicine. She received her MD from Capital University of Medicine in Beijing, China and her MS in molecular pathology from Beijing Union Medical College. She is board certified by the American Board of Medical Genetics, with a subspecialty in clinical molecular genetics, and certified with the New York State Department of Health, with a subspecialty in genetic testing. She is a member of several professional societies, including American College of Medical Genetics and Genomics, Association for Molecular Pathology, and American Society of Human Genetics. Her research interests include the genotype-phenotype correlations in inborn errors of metabolism and genetic diseases in the RAS/MAPK pathway; she is also involved with implementing next-generation sequencing techniques into molecular diagnostics.
  • Medical Director, Toxicology and Pharmacogenetics
    Dr. McMillin is a professor of pathology at the University of Utah School of Medicine. She received her PhD in pharmacology and toxicology from the University of Utah and is certified by the American Board of Clinical Chemistry in clinical chemistry and toxicological chemistry. Dr. McMillin is actively involved in professional associations such as the International Association of Therapeutic Drug Monitoring and Clinical Chemistry (IATDMCT), the American Association for Clinical Chemistry (AACC), and the College of American Pathologists (CAP). Her primary interests include detection of neonatal drug exposures, pain management, and clinical applications and implementation of pharmacogenomics.
  • Medical Director, Hematopathology
    Co-Chief, Clinical Pathology
    Vice Chair, Pathology
    Senior Vice President, Research and Development
    Executive Director, ARUP Institute for Clinical & Experimental Pathology
    Dr. Perkins, a tenured professor at the University of Utah School of Medicine, has been with ARUP and the University of Utah for more than 20 years and has served in numerous leadership positions, including director of hematopathology, interim department chair, Co-Chief for the Clinical Pathology Division, and, for the past eight years, a member of ARUP Laboratories’ executive management team. She is board certified in anatomic pathology, with a special qualification in hematology. Dr. Perkins received her PhD in biochemistry from the University of Miami, and earned her MD and completed her pathology residency at Washington University in St. Louis and did a hematopathology fellowship at the University of Utah. She completed her hematopathology fellowship under Dr. Carl Kjeldsberg at the University of Utah and has published more than 200 peer-reviewed articles and 70 book chapters.
  • Chief, Hematopathology
    Director, Hematopathology Fellowship Program
    Dr. Salama is professor of pathology, chief of hematopathology, and director of the Hematopathology Fellowship Program at the University of Utah School of Medicine. Dr. Salama received his MD from Cairo University and completed a hematopathology fellowship at the University of New Mexico and a surgical pathology fellowship at Stanford University. He is certified by the American Board of Pathology in anatomic pathology and hematopathology. His areas of interest span all aspects of hematopathology, including morphology, specialized studies of bone marrow and lymph node, and digital pathology.
  • Medical Director, Solid Tumor Molecular Diagnostics and Histology
    Staff Pathologist, Anatomic Pathology
    Dr. Samowitz is a professor of pathology at the University of Utah School of Medicine. He received his MD from SUNY Downstate, and completed residency training in anatomic pathology at the University of Chicago and fellowships in gastrointestinal pathology at Johns Hopkins Hospital. Specializing in gastrointestinal pathology and the molecular genetics of colorectal cancer, Dr. Samowitz is also the medical director for numerous molecular tests in solid tumor molecular diagnostics, including single-gene assays and next-generation sequencing panels.