| Methodology: |
Routine Cytopathologic Evaluation
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| Performed: |
Mon-Fri
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| Reported: |
1-5 days
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| Specimen Required: |
Collect: and Transport:
Indications: Breast ductal lavage is intended as a cytologic screening evaluation for premalignant and malignant changes in women with high risk of breast carcinoma.
Specimen Required: Breast ductal lavage fluid.
Supplies: Ductal lavage collection system and transport tube, cytologic fixative, and ARUP Cytology test request form.
Collection Procedure: Ductal lavage is performed at the clinician's office. Portions of the breast duct system are infused with a small amount of saline. A total of 10-20 mL of saline is introduced in 2-4 mL increments. Saline rinses the ducts and collects epithelial cells. The fluid in the collection syringe is transferred to a vial containing cell fixative (CytoLyt, CytoRich™ Red, or 50% alcohol). Mix ductal lavage fluid with an equal volume (1:1) of cytologic fixative. The specimen should be labeled with the patient's first and last name, date of birth, sample type, left or right breast designation, ductal orifice identification number (fluid from each duct must be kept separate (i.e. not pooled)), medical record number (or other unique identifier), and collection date, placed in a specimen bag, and shipped to the Cytopathology Laboratory at ARUP. The specimen should be stored and transported at 2-8°C, and must be accompanied by an ARUP Cytology test request form with the requested test marked, left or right breast designation, ductal orifice identification number, and pertinent clinical history.
Transport: If collected in Surepath™, CytoLyt, or CytoRich:
Submit specimen according to Biological Substance, Category B, shipping guidelines.
Pediatric Collection/Transport:
Submit specimen according to Biological Substance, Category B, shipping guidelines.
Unacceptable Conditions: Refer to specimen rejection in the Cytopathology section in the front of this User's Guide.
Stability: Refrigerated: 5 days
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