ARUP's Laboratory Test Directory

Allergen, Insect and Venom, Bumble Bee Venom IgE : 2007627

Mnemonic: BUMBLEBEE

Methodology: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Patient Prep: Multiple patient encounters should be avoided.

Collect: Serum separator tube. Multiple specimen tubes should be avoided.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.25 mL serum plus 0.1 mL for each additional allergen ordered to an ARUP Standard Transport Tube. (Min: 0.25 mL plus 0.04 mL for each allergen ordered)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Hemolyzed, icteric, or lipemic specimens

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval:
Less than 0.10 kU/L: No significant level detected
0.10-0.34 kU/L: Clinical relevance undetermined
0.35-0.70 kU/L: Low
0.71-3.50 kU/L: Moderate
3.51-17.50 kU/L: High
17.51 kU/L or Greater: Very High
Interpretive Data: Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.

See Compliance Statement A: www.aruplab.com/CS
Note: Note: Due to the rise and fall of circulating specific IgE antibodies to insect venom, blood samples for allergen testing should be collected no sooner than 2-3 weeks and no later than 6 months after an insect sting.
CPT Code(s): 86003