ARUP's Laboratory Test Directory

Anti-C1q Antibody, IgG : 2007601
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Additional Technical Information
  


Mnemonic: ANTI-C1Q

Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed: Mon
Reported: 1-8 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Urine or plasma. Contaminated, heat-inactivated, severely hemolyzed or severely lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
0-19 Units Negative
20-39 Units Equivocal
40 Units or greater Positive

Interpretive Data: The presence of the anti-C1q IgG antibody may be associated with increased risk of lupus nephritis or with systemic lupus erythematosus (SLE) global activity. Anti-C1q antibodies are not specific for SLE; strong clinical correlation with disease is recommended.

See Compliance Statement A: www.aruplab.com/CS
CPT Code(s): 83516
Cross References: Anti-Complement (Anti-C1q Antibody, IgG), Lupus Nephritis (Anti-C1q Antibody, IgG, Systemic Lupus Erythematosus (SLE) (Anti-C1q Antibody, IgG)