ARUP's Laboratory Test Directory

Pain Management Drug Panel by High-Resolution Time-of-Flight Mass Spectrometry and Enzyme Immunoassay, Urine : 2007479

Mnemonic: PAIN HYB U

Methodology: Qualitative Liquid Chromatography/Time of Flight Mass Spectrometry/Enzyme Immunoassay/Quantitative Spectrophotometry
Performed: Sun-Sat
Reported: 1-3 days
Specimen Required: Collect: Random urine.

Specimen Preparation: Transfer 4 mL each into two (2) ARUP Standard Transport Tubes urine with no additives or preservatives. (Min: 2 mL each)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles.

Stability (collection to initiation of testing): Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years

Reference Interval:
 

Drugs covered and range of cutoff concentrations. Note that some drugs are identified based on the presence of unique drug metabolites not listed below.
 
Drugs/Drug Classes Range of Cutoff Concentrations
Barbiturates 200 ng/mL
Benzodiazepine-like:
alprazolam, clonazepam, diazepam, lorazepam, midazolam, nordiazepam, oxazepam,  temazepam, zolpidem
20 - 60 ng/mL
Cannabinoids (11-nor-9-carboxy-THC) 20 ng/mL
Ethyl Glucuronide 500 ng/mL
Muscle Relaxant(s):
carisoprodol
100 ng/mL
Opiates/Opioids:
buprenorphine, codeine, dihydrocodeine, fentanyl, heroin, hydrocodone, hydromorphone, meperidine, methadone, morphine, oxycodone, oxymorphone, propoxyphene, tapentadol, tramadol
2-300 ng/mL
Phencyclidine (PCP) 25 ng/mL
Stimulants:
amphetamine, cocaine, methamphetamine, methylphenidate, MDMA (Ecstasy), MDEA (Eve), MDA, phentermine
100-400  ng/mL

Interpretive Data: Methodology: Qualitative Enzyme Immunoassay and Qualitative Liquid Chromatography-Time-of-Flight-Mass Spectrometry, Quantitative Spectrophotometry

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration must be greater than or equal to the cutoff concentration to be reported as present. If specific drug concentrations are required, contact the laboratory within two weeks of specimen collection to request confirmation and quantification by a second analytical technique. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.
Note: Creatinine concentration is also provided.
CPT Code(s): 80100; 80101 x8; (HCPCS: G0431).
Cross References: Comprehensive hybrid, TOF, high res, high-res , Pain management, (drug screen, targeted, urine)