ARUP's Laboratory Test Directory

Rapid Plasma Reagin (RPR) with Reflex to RPR Titer or T. pallidum Antibody by Particle Agglutination : 2007443

Mnemonic: RPR REV

Ordering Recommendation: Order to confirm a reactive treponemal screening test (eg, CIA, EIA) when using the reverse testing algorithm to screen for syphilis. For traditional CDC recommended algorithm, refer to Rapid Plasma Reagin (RPR) with Reflex to Titer and TP-PA Confirmation (0050478).
Methodology: Semi-Quantitative Charcoal Agglutination/Semi-Quantitative Particle Agglutination
Performed: Sun-Sat
Reported: 1-4 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.25 mL) Do not freeze. Also acceptable: Plasma, if testing is completed within 48 hours of collection.

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: CSF or other body fluids.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
 
Test Number Components Reference Interval
0050471Rapid Plasma Reagin (RPR) with Reflex to Titer  
 
Test Code Components Reference Interval
 Rapid Plasma Reagin (RPR) RPR (+) = Reactive
RPR (-) = Nonreactive
 Rapid Plasma Reagin (RPR) Titer < 1:1
0050477Treponema pallidum Antibody (FTA-ABS), Serum, IgG by IFA with Reflex to Treponema pallidum Antibody by TP-PA  
 
Test Code Components Reference Interval
 T.Pallidum Ab, IgG (FTA-ABS) Nonreactive
0050777 Treponema pallidum Antibody by TP-PA Nonreactive

Note: If RPR is reactive, then a titer to endpoint will be added. If RPR is nonreactive, a TP-PA (MHA) confirmation will be added. Additional charges apply.
CPT Code(s): 86592 RPR; if reflexed, add (nonreactive) TP-PA 86780 or (reactive) 86593 RPR titer
Cross References: Rapid Plasma Reagin (RPR) with MHA-TP Confirmation, Rapid Plasma Reagin (RPR), Reverse Algorithm, Syphilis Reverse Algorithm, RPR (Diagnosis) with Reflex to Titer and Confirmatory Testing, RPR with MHA-TP Confirmation, Treponema pallidum (Rapid Plasma Reagin) with Reflex to Titer & TP-PA Confirmation