ARUP's Laboratory Test Directory

IDH1 R132H Point Mutation with Interpretation by Immunohistochemistry : 2007357

Mnemonic: IDH1 IP

Methodology: Immunohistochemistry
Performed: Mon-Fri
Reported: 1-5 days
Specimen Required: Collect: Tumor tissue.

Specimen Preparation: Formalin fix (10 percent neutral buffered formalin is preferred) and paraffin embed specimen. Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800)522-2787. (Min. 3 slides) If sending precut slides, do not oven bake.

Storage/Transport Temperature: Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.

Remarks: This test code includes pathologist interpretation. Include surgical pathology report. When ordering, please identify tissue site. IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. For additional technical details, please contact ARUP Client Services at (800) 522-2787.

Unacceptable Conditions: Paraffin block with no tumor tissue remaining.

Stability (collection to initiation of testing): Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Interpretive Data: By report

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 88342
Cross References: Astrocytoma and Oligodendroglioma Tumor Cell Marker