ARUP's Laboratory Test Directory

Free Estradiol by ED/LC-MS/MS : 2006160

Mnemonic: ESDIOL FR

Ordering Recommendation: Direct measure of free estradiol in serum. Most accurate measure of bioactive estradiol.
Methodology: Quantitative Equilibrium Dialysis/High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed: Tue, Fri
Reported: 1-6 days
Specimen Required: Collect: Serum separator tube or green (sodium or lithium heparin), Red Top, Plasma Separator Tube.

Specimen Preparation: Separate from cells ASAP or within 2 hours of collection. Transport 2 mL serum or plasma. (Min: 1.0 mL)

Storage/Transport Temperature: Frozen.

Stability (collection to initiation of testing): After separation from cells: Ambient: unacceptable; Refrigerated: 1 week; Frozen: 6 months

Reference Interval:
Age/Gender Reference Interval
Adult Females - 19 years and older: Follicular Stage
Mid-Cycle Stage
Luteal Stage
Post-Menopausal Stage
less than 2.4 pg/mL
less than 3.1 pg/mL
less than 2.6 pg/mL
less than or equal to 0.5 pg/mL
Adult Males By report
Children By report

Interpretive Data:

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 82670
Cross References: High-Sensitivity Free Estradiol