ARUP's Laboratory Test Directory

Japanese Encephalitis Virus Antibody, IgG by ELISA : 2005687

Mnemonic: JPN G

Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed: Thu
Reported: 1-8 days
Specimen Required: Collect: Serum separator tube

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature: Refrigerated

Unacceptable Conditions: Contaminated or heat-inactivated specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles).
Reference Interval:
Effective January 17, 2012
Japanese Encephalitis Virus Antibody IgG
1.9 IV or less Negative - No significant level of detectable Japanese encephalitis virus (JEV) IgG antibody.
2.0 - 4.9 IV Equivocal - Questionable presence of JEV IgG antibody. Repeat testing in 10-14 days may be helpful.
5.0 IV or greater Positive - JEV IgG antibody detected, which may indicate a current or past infection.

Interpretive Data: A positive result does not necessarily rule out infection with a different Flavivirus spp. Patients in the early stage of JEV infection may not have a detectable level of IgG antibody; IgG response may take several days or weeks to develop. In the absence of detectable IgG, testing for IgM-class antibody is strongly recommended. The best evidence of current infection is a significant change on two appropriately timed specimens with both tests performed in the same laboratory at the same time.

See Compliance Statement D: www.aruplab.com/CS
CPT Code(s): 86790