ARUP's Laboratory Test Directory

Endomysial Antibody, IgG : 2005501
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Additional Technical Information
  


Mnemonic: EMA IGG

Ordering Recommendation: Use in IgA-deficient individuals; acceptable single screening test for celiac disease. Acceptable follow-up test for weakly positive or negative tissue transglutaminase IgG screen. Celiac Disease Reflexive Panel (0051065) is the preferred screening test for individuals with high suspicion for IgA deficiency or patients at-risk for celiac disease who should undergo small bowel biopsy to confirm disease.
Methodology: Semi-Quantitative Indirect Fluorescent Antibody
Performed: Tue
Reported: 1-8 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Contaminated specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
Effective November 14, 2011

Less than 1:10
Interpretive Data: The presence of endomysial antibodies IgG, may be useful in identifying IgA-deficient patients at risk for celiac disease. To establish the diagnosis of celiac disease, a positive result must be confirmed through a biopsy of the small intestine.

See Compliance Statement D: www.aruplab.com/CS
CPT Code(s): 86256
Cross References: IgA Deficient Celiac Disease (Endomysial Antibody, IgG)