ARUP's Laboratory Test Directory

Prothrombin Antibodies, IgG & IgM : 2004411

Mnemonic: PROTHROMPN

Ordering Recommendation: Preferred second-line testing for strong suspicion of seronegative antiphospholipid syndrome (APS). Order incrementally or concurrently with other non-criteria antiphospholipid antibody tests.
Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed: Mon
Reported: 1-8 days
Specimen Required: Collect: Serum separator tube or lt. blue (sodium citrate).

Specimen Preparation: Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Hemolyzed, grossly icteric, or lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval:
 
Test Number Components Reference Interval
0051302Prothrombin Antibody, IgG Less than 20.0 Units
0051303Prothrombin Antibody, IgM Less than 20.0 Units

CPT Code(s): 86849 x2
Cross References: Anti-Prothrombin Antibodies (Prothrombin Antibodies, IgG & IgM), Antiprothrombin Antibodies (Prothrombin Antibodies, IgG & IgM), aPT Antibodies (Prothrombin Antibodies, IgG & IgM)