ARUP's Laboratory Test Directory

von Willebrand Panel with Reflex to von Willebrand Multimeric Analysis : 2003387
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Additional Technical Information
  


Mnemonic: VW PANEL R

Ordering Recommendation: Recommended reflex panel to diagnose and subclassify suspected von Willebrand disease.
Methodology: Electrophoresis/Western Blot/Clotting/Microlatex Particle-Mediated Immunoassay/Platelet Agglutination
Performed: Mon-Sat
Reported: 1-11 days
Specimen Required: Collect: Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation: Transfer 3 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1.5 mL)

Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions: Serum. Non-frozen or hemolyzed specimens.

Stability (collection to initiation of testing): Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months; Frozen at -70°C: 6 months
Reference Interval:
 
Available Separately Components Reference Interval
0092281von Willebrand Factor Multimers By report
0030095Factor VIII, Activity 0-6 years: 56-191%
7-9 years: 76-199%
10-11 years: 80-209%
12-13 years: 72-198%
14-15 years: 69-237%
16-17 years: 63-221%
18 years and older: 56-191%
0030285von Willebrand Factor Antigen 0-6 years: 52-214%
7-9 years: 62-180%
10-11 years: 63-189%
12-13 years: 60-189%
14-15 years: 57-199%
16-17 years: 50-205%
18 years and older: 52-214%
0030250von Willebrand Factor Activity (Ristocetin Cofactor) 0-6 years: 51-215%
7-9 years: 52-176%
10-11 years: 60-195% 
12-13 years: 50-184%
14-15 years: 50-203 %
16-17 years: 49-204%
18 years and older: 51-215%

Note: If von Willebrand ristocetin cofactor (RCF) or von Willebrand factor antigen (vWF Ag) or Factor VIII is low, von Willebrand Multimeric Analysis testing will be added.  If the ratio of RCF/vWF Ag is less than 0.7, vW Multimeric Analysis testing will be added.
CPT Code(s): 85240 F8; 85246 vWF/AG; 85245 RCF; If reflexed add 85247 vW Multi