ARUP's Laboratory Test Directory

Cortisol by LC-MS/MS, Serum or Plasma : 2003250

Mnemonic: CORT TMS

Methodology: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed: Mon,Thu
Reported: 1-6 days
Specimen Required: Patient Prep: It is recommended that the specimen be collected between 6-11 a.m.

Collect: Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transport 1 mL serum or plasma. (Min: 0.5 mL)

Storage/Transport Temperature: Frozen.

Unacceptable Conditions: Room temperature specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months
Reference Interval:
Adult Reference Ranges for Cortisol, Serum, µg/dL
AM 4.6-20.6 µg/dL
PM 1.8-13.6 µg/dL
Stimulation 30-60 Minutes Post 0.25 mg Cosyntropin IV Greater than 20.0 µg/dL

Pediatric Reference Ranges for Cortisol, Serum, µg/dL
AM
1-12 months 4.6-23.0 µg/dL
1-5 years 6.0-25.0 µg/dL
6-17 years 4.6-15.0 µg/dL
Stimulation 30-60 Minutes Post 0.25 mg Cosyntropin IV
1-12 months 32.0-60.0 µg/dL
1-5 years 22.0-40.0 µg/dL
6-17 years 17.0-28.0 µg/dL

Interpretive Data:

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 82533