ARUP's Laboratory Test Directory

Human Papillomavirus (HPV) Low Risk by in situ Hybridization, Paraffin : 2002896

Mnemonic: HPVLOW ISH

Ordering Recommendation: Low-risk HPV testing (genotypes 6,11) is not currently part of recommended cervical cancer screening guidelines.
Methodology: In situ Hybridization
Performed: Mon-Thu
Reported: 2-5 days
Specimen Required: Collect: Tissue.

Specimen Preparation: Formalin fix (10% neutral buffered formalin) and paraffin embed tissue. Transport tissue block or 5 sections on "plus" (positively) charged or silanized slides. (Min: 3 slides) Protect from excessive heat.

Storage/Transport Temperature: Room temperature. Ship in cooled container during summer months.

Unacceptable Conditions: Specimens in fixative other than 10% neutral buffered formalin. Decalcified specimens.

Stability (collection to initiation of testing): Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Reference Interval:
Negative
Interpretive Data: This test detects genotypes: 6,11.

A negative result does not rule out the presence of an HPV genotype absent from the test panel, a low level infection, or specimen sampling error.

See Compliance Statement A: www.aruplab.com/CS
CPT Code(s): 88365
Cross References: HPV (Human Papillomavirus (HPV) Low Risk by in situ Hybridization, Paraffin), HPV Low Risk ISH (Human Papillomavirus (HPV) Low Risk by in situ Hybridization, Paraffin), HPVLOW ISH (Human Papillomavirus (HPV) Low Risk by in situ Hybridization, Paraffin), Human Papillomavirus (Human Papillomavirus (HPV) Low Risk by in situ Hybridization, Paraffin)