ARUP's Laboratory Test Directory

Tramadol and Metabolites - Confirmation/Quantitation - Urine : 2002736

Mnemonic: TRAMAD UR

Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed: Tue
Reported: 1-7 days
Specimen Required: Collect: Random urine.

Specimen Preparation: Transfer 2 mL urine with no additives or preservatives an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature: Room temperature.

Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles.

Stability (collection to initiation of testing): Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years
Interpretive Data: Methodology: LC-MS/MS

Drugs covered: Tramadol, n-desmethyltramadol (qualitative only), and o-desmethyltramadol (qualitative only).

Positive cutoff:
 Tramadol: 50 ng/mL
n-desmethyltramadol: 100 ng/mL
o-desmethyltramadol: 100 ng/mL

For medical purposes only; not valid for forensic use.

The presence of metabolite(s) without parent drug is common and may indicate use of parent drug during the prior week.

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 83925
Cross References: N-Desmethyltramadol (Tramadol & Metabolites - Confirmation/Quantitation - Urine), O-Desmethyltramadol (Tramadol & Metabolites - Confirmation/Quantitation - Urine), Pain Management (Tramadol & Metabolites - Confirmation/Quantitation - Urine), Pain Management, Tramadol, Quantitative, w/ medMATCH, Urine (Tramadol & Metabolites - Confirmation/Quantitation - Urine) , Ryzolt (Tramadol & Metabolites - Confirmation/Quantitation - Urine), Tramal (Tramadol & Metabolites - Confirmation/Quantitation - Urine), Ultracet (Tramadol & Metabolites - Confirmation/Quantitation - Urine), Ultram (Tramadol & Metabolites - Confirmation/Quantitation - Urine)