ARUP's Laboratory Test Directory

Acute Myelogenous Leukemia (AML) with Myelodysplastic Syndrome (MDS) or Therapy-Related AML, by FISH : 2002653
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Time Sensitive
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Additional Technical Information


Mnemonic: F TAML MDS

Methodology: Fluorescence in situ Hybridization
Performed: Sun-Sat
Reported: 3-10 days
Specimen Required: Collect: Non-diluted bone marrow aspirate collected in a heparinized syringe. Also acceptable: Whole blood in green (sodium heparin).
Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.

Specimen Preparation: Transfer bone marrow to a green (sodium heparin). Transport 3 mL bone marrow OR 5 mL whole blood. (Min: 1 mL bone marrow OR 2 mL whole blood)

Storage/Transport Temperature: Room temperature.

Remarks: If cell pellets or dropped cytogenetics slides are submitted, a processing fee will not apply. This test must be ordered using Cytogenetic test request form (#43099) or through your ARUP interface.

Unacceptable Conditions: Frozen specimens. Clotted or paraffin-embedded specimens.

Stability (collection to initiation of testing): Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
Reference Interval:
By report
Interpretive Data: Probes included: EGR1 (5q del), D7S486 (7q del/-7), MLL

See Compliance Statement A: www.aruplab.com/CS
Note: A processing fee will be charged if this procedure is canceled, at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth.  The fee will vary based on specimen type. To order probes separately, refer to Chromosome FISH, Interphase (2002298).
CPT Code(s): 88271 x3; 88275 x3; 88291
Cross References: Chromosome Analysis (Acute Myelogenous Leukemia (AML) with Myelodysplastic Syndrome (MDS), or Therapy-Related AML, by FISH)