ARUP's Laboratory Test Directory

Pancreatobiliary FISH : 2002461

Mnemonic: PF

Methodology: Fluorescence in situ Hybridization/Automated Image Analysis or Manual Screening
Performed: Weekly
Reported: 4-12 days
Specimen Required: Collect: Bile or pancreatic duct brushings, biliary stent, fine needle aspirates, or pancreatic juices.

Specimen Preparation: Place specimen in Cytolyt® or PreservCyt® fixative vial. If the specimen is a brushing, submit the brush in the fixative. Label specimen with the patient's first and last name, date of birth, specimen source, medical record number (or other unique identifier), and collection date.

Storage/Transport Temperature: Refrigerated.

Remarks: Completed Cytology request form required.

Unacceptable Conditions: Specimens not collected in Cytolyt® or PreservCyt® fixative.

Stability (collection to initiation of testing): Ambient: Unacceptable; Refrigerated: 72 hours; Frozen: Unacceptable
Reference Interval:
Effective November 14, 2011
Negative No evidence of numeric chromosomal abnormalities associated with pancreatobiliary carcinoma.
Positive Contains numeric chromosomal abnormalities associated with pancreatobiliary carcinoma.

Interpretive Data: Negative: A negative result indicates that none of the numeric chromosomal abnormalities commonly associated with pancreatobiliary carcinoma were identified within this specimen. A negative result does not exclude the possibility of pancreatobiliary carcinoma. In the presence of other evidence suggesting pancreatobiliary carcinoma, additional clinical studies should be considered.

Positive: A positive result indicates that one or more numeric chromosomal abnormalities commonly associated with pancreatobiliary carcinoma were identified within this specimen

Refer to Statement B under Testing Information at http://www.aruplab.com.
Note: The UroVysion™ Kit is designed to detect aneuploidy for chromosomes 3, 7 and 17via fluorescence in situ hybridization (FISH). Results from this test are intended for use, in conjunction with and not in lieu of current standard diagnostic procedures, as an aid for initial diagnosis of pancreatobiliary carcinoma.
CPT Code(s): 88367 x3; If manual: 88368 x3
Cross References: Bile Duct (Pancreatobiliary FISH), Bile Duct Cancer (Pancreatobiliary FISH), Cholangiocarcinoma (Pancreatobiliary FISH), FISH, Bile Duct (Pancreatobiliary FISH), FISH, Pancreas (Pancreatobiliary FISH), Pancreatic Adenocarcinoma (Pancreatobiliary FISH), Pancreatic Cancer (Pancreatobiliary FISH)
 
 

 

 

 
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