ARUP's Laboratory Test Directory

Pancreatobiliary FISH : 2002461

Mnemonic: PF

Methodology: Fluorescence in situ Hybridization/Automated Image Analysis or Manual Screening
Performed: Weekly
Reported: 4-12 days
Specimen Required: Collect: Indications: The Vysis® UroVysion™ Kit is designed to detect aneuploidy for chromosomes 3, 7, 17, and loss of the 9p21 locus via fluorescence in situ hybridization (FISH). Results from the UroVysion™ Kit are intended for use, in conjunction with and not in lieu of current standard diagnostic procedures, as an aid for initial diagnosis of pancreatic carcinoma.
Specimen Required: Bile duct brushing collected in Cytolyt® (preferred) or PreservCyt® fixative.
Supplies: Cytolyt® or PreservCyt® fixative.
Collection Procedure: Rinse Bile Duct Brushing in Cytolyt® or PreservCyt® fixative vial. The specimen should be labeled with the patient's first and last name, date of birth, specimen source, medical record
number (or other unique identifier), and collection date. Submit the specimen along with the completed Cytology request form to the Cytopathology Laboratory. The specimen must be accompanied by a Cytology
test request form with the requested test marked and pertinent clinical history recorded.


Storage/Transport Temperature:

Unacceptable Conditions: Specimens not collected in Cytolyt® or PreservCyt® fixative.

Stability (collection to initiation of testing): Refrigerated: 3 days (must be in Cytolyt® or PreservCyt® fixative)
Reference Interval:
Negative: No evidence of numeric chromosomal abnormalities associated with pancreatic carcinoma.
Positive: Contains numeric chromosomal abnormalities associated with pancreatic carcinoma
Interpretive Data: Negative: A negative result indicates that none of the numeric chromosomal abnormalities commonly associated with pancreatic carcinoma were identified within this specimen. A negative result does not exclude the possibility of pancreatic carcinoma. In the presence of other evidence suggesting pancreatic carcinoma, additional clinical studies should be considered.

Positive: A positive result indicates that one or more numeric chromosomal abnormalities commonly associated with pancreatic carcinoma were identified within this specimen

Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory.
CPT Code(s): 88367 x4; If manual: 88368 x4
 
 

 

 

 
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