ARUP's Laboratory Test Directory

Eosinophilia Panel by FISH : 2002378
[ image for: Time Sensitive]
Time Sensitive
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Additional Technical Information


Mnemonic: FISH EOS P

Ordering Recommendation: Aids in diagnosis and classification of hematopoietic neoplasms presenting with prominent eosinophilia. Does not detect rearrangements associated with chronic myelogenous leukemia.
Methodology: Fluorescence in situ Hybridization
Performed: Sun-Sat
Reported: 3-10 days
Specimen Required: Collect: Non-diluted bone marrow aspirate collected in a heparinized syringe.Also acceptable: Green (sodium heparin).
Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.

Specimen Preparation: Transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL). OR transport 5 mL whole blood (Min: 2 mL)

Storage/Transport Temperature: Room temperature.

Remarks: If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
This test must be ordered using Cytogenetic test request form #43097 or through your ARUP interface. Submit the Patient
History for Cytogenetic (Chromosome) Studies form with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).

Unacceptable Conditions: Frozen specimens. Paraffin-embedded specimens. Clotted specimens.

Stability (collection to initiation of testing): Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
Reference Interval:
By report
Interpretive Data: Probes included: PDGFR-alpha, PDGFR-beta, FGFR1, and CBFB.

See Compliance Statement A: www.aruplab.com/CS
Note: A processing fee will be charged if this procedure is canceled, at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth. The fee will vary based on specimen type.
CPT Code(s): 88271 x4; 88275 x4; 88291
Cross References: FISH, Myeloproliferative Neoplasms (Eosinophilia) (Eosinophilia Panel by FISH)