ARUP's Laboratory Test Directory

Chromosome FISH, CLL Panel : 2002295
[ image for: Cytogenetics Test Request Form Required]
Cytogenetics Test Request Form Required
[ image for: Patient History For Cytogenetic (Chromosome) Studies]
Patient History For Cytogenetic (Chromosome) Studies


Mnemonic: FISH CLLP

Methodology: Fluorescence in situ Hybridization
Performed: Sun-Sat
Reported: 3-10 days
Specimen Required: Collect: Green (sodium heparin). Also acceptable: Non-diluted bone marrow aspirate collected in a heparinized syringe.

Specimen Preparation: Transport 10 mL whole blood (Min: 2 mL). OR Transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL)

Storage/Transport Temperature: Room temperature.

Remarks: It is recommended that all FISH studies be done in conjunction with routine cytogenetic analysis. (Refer to appropriate Chromosome Analysis test for order instructions). If FISH only is requested, please submit a copy of previous cytogenetics report.
If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
This test must be ordered using Cytogenetic test request form #43099 or through your ARUP interface. Submit the Patient History for Cytogenetic (Chromosome) Studies form with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).

Unacceptable Conditions: Frozen specimens. Paraffin-embedded specimens. Clotted specimens.

Stability (collection to initiation of testing): Ambient: Whole Blood: 48 hours, Bone Marrow: 24 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Reference Interval:
By report
Interpretive Data:

Refer to Statement A under Testing Information at http://www.aruplab.com.
Note: Fluorescence in situ Hybridization panel is performed for CLL prognosis-specific genomic abnormalities as follows: ATM deletion, D13S319 deletion, Trisomy 12, TP53 deletion.

A processing fee will be charged if this procedure is canceled at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth
CPT Code(s): 88271 x4 DNA probe; 88275 x4 Chromosomal in situ hybridization 100-300 cells; 88291 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders
Cross References: Chromosome Analysis (Chromosome FISH, CLL Panel), Chronic Lymphocytic Leukemia (Chromosome FISH, CLL Panel)
 
 

 

 

 
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