ARUP's Laboratory Test Directory

Chromosome Analysis, Chorionic Villus : 2002291
[ image for: Time Sensitive]
Time Sensitive
[ image for: Patient History for Prenatal Cytogenetics]
Patient History for Prenatal Cytogenetics


Mnemonic: CHR CVS

Methodology: Giemsa Band
Performed: Sun-Sat
Reported: 7-14 days
Specimen Required: Collect: Thaw media prior to collection. Chorionic villus in a sterile, screw-top container filled with tissue culture transport medium (ARUP Supply #32788). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. If cytogenetics tissue media is not available, collect in plain RPMI, Hanks solution, saline, or ringers.

Specimen Preparation: DO NOT FREEZE. Do not place in formalin. Transport chorionic villus (CVS) specimen in a sterile, screw-top container filled with tissue culture transport medium. If specimen size is too large for a normal collection tube, a larger sterile container can be used such as a sterile urine cup and can be flooded with several tubes of cytogenetic tissue media.

Storage/Transport Temperature: Room temperature

Remarks: This test must be ordered using Cytogenetic test request form #43097 or through your ARUP interface. Submit the Patient History for Prenatal Cytogenetics form with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).

Unacceptable Conditions: Frozen specimens. Specimens preserved in formalin.

Stability (collection to initiation of testing): Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
Reference Interval:
By report
Interpretive Data: Counseling and informed consent are recommended for genetic testing. Consent forms are available online at www.aruplab.com.
Note: These studies involve culturing of living cells; therefore, turnaround times given represent average times which are subject to multiple variables. After specimen receipt, results are generally available in an average of 12 days.

A processing fee to cover sex confirmation and rule out maternal contamination by FISH is added to all Chromosome Analysis, Chorionic Villus Sampling (CVS) tests. An additional processing fee will be charged if this procedure is canceled at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth.
CPT Code(s): 88269; 88235; 88280; 88291
Cross References: 45,X, 45X, ambiguous genitalia, cardiac defect, chorionic villi, CVS, cystic hygroma, Down syndrome, Down’s syndrome, Downs syndrome, Edward’s, Edwards, heart defect, Increased NT, inversion, Karotype (Chromosome Analysis, Chorionic Villus), karyotype, karyotypes, Kleinfelter syndrome, Klienfelter syndrome, Klinefelter syndrome, MCA, monosomy, multiple congenital abnormalities, multiple congenital anomalies, NT, nuchal translucency, Pateau, prenatal, sex chromosome, T13, T18, T21, translocation, trisomy, trisomy 13, trisomy 18, trisomy 21, Turner syndrome, Turner’s syndrome, Turners syndrome, villi, XO, XXY syndrome, XYY syndrome