ARUP's Laboratory Test Directory

Protein S, Free Antigen with Reflex to Protein S, Total Antigen : 2002269

Mnemonic: PRS FREE R

Methodology: Microlatex Particle-Mediated Immunoassay (LIA)
Performed: Mon-Fri
Reported: 1-4 days
Specimen Required: Collect: Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation: Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Remarks:

Unacceptable Conditions: Serum. Non-frozen or hemolyzed specimens.

Stability (collection to initiation of testing): Ambient: 2 hours; Refrigerated: 4 hours; Frozen: 2 weeks
Reference Interval:
1-89 days: 15-55%
90-179 days: 35-92%
180-364 days: 45-115%
1-5 years: 62-120%
6-9 years: 62-130%
10-17 years: 60-140%
18 years and older Male: 74-147%
18 years and older Female: 55-123%
Interpretive Data: Patients on oral anticoagulants may have decreased free protein S values.  Patients should be off oral anticoagulant therapy for two weeks for accurate measurement of free protein S levels.  Decreased levels of free protein S are also associated with DIC, liver disease, pregnancy, and inflammatory syndromes.
Note: If low Protein S Free Antigen is detected, then Protein S, Total Antigen, will be added. Additional charges apply.
CPT Code(s): 85306; if reflexed, add: 85305
Cross References: Protein S Profile (Protein S, Free Antigen with Reflex to Protein S, Total Antigen)
 
 

 

 

 
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