ARUP's Laboratory Test Directory

Meningoencephalitis Panel, CSF with Reflex to HSV Type 1 and Type 2 Glycoprotein G-Specific Ab, IgG : 2001765

Mnemonic: MENINGCSFR

Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Chemiluminescent Immunoassay
Performed: Tue, Fri
Reported: 2-6 days
Specimen Required: Collect: CSF.

Specimen Preparation: Transfer 3 mL CSF to an ARUP Standard Transport Tube. (Min: 2 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Serum or plasma. Contaminated or heat-inactivated specimens.

Stability (collection to initiation of testing): Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval:
Effective February 19, 2013
Test Number Components Reference Interval
0098893California Encephalitis Antibody, IgG by IFA, CSF Less than 1:1
0098898California Encephalitis Antibody, IgM by IFA, CSF Less than 1:1
0098896Eastern Equine Encephalitis Antibody, IgG by IFA, CSF Less than 1:1
0098729Eastern Equine Encephalitis Antibody, IgM by IFA, CSF Less than 1:1
0098895St. Louis Encephalitis Antibody, IgG by IFA, CSF Less than 1:1
0098899St. Louis Encephalitis Antibody, IgM by IFA, CSF Less than 1:1
0098897Western Equine Encephalitis Antibody, IgG by IFA, CSF Less than 1:1
0098730Western Equine Encephalitis, Antibody, IgM by IFA, CSF Less than 1:1
0050238West Nile Virus Antibody, IgG by ELISA, CSF 1.29 IV or less: Negative - No significant level of West Nile virus IgG antibody detected.
1.30-1.49 IV: Equivocal - Questionable presence of West Nile virus IgG antibody detected. Repeat testing in 10-14 days may be helpful.
1.50 IV or greater: Positive - Presence of IgG antibody to West Nile virus detected, suggestive of current or past infection.
0050239West Nile Virus Antibody, IgM by ELISA, CSF 0.89 IV or less: Negative - No significant level of West Nile virus IgM antibody detected.
0.90-1.10 IV: Equivocal - Questionable presence of West Nile virus IgM antibody detected. Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - Presence of IgM antibody to West Nile virus detected, suggestive of current or recent infection.
0054440Measles (Rubeola) Antibody, IgG, CSF Effective August 20, 2012

24.9 AU/mL or less: Negative - No significant level of IgG antibody to measles (rubeola) virus detected.
25.0-29.9 AU/mL: Equivocal - Repeat testing in 10-14 days may be helpful.
30.0 AU/mL or greater: Positive - IgG antibody to measles (rubeola) detected, which may indicate a current or past measles (rubeola) infection.
0054441Measles (Rubeola) Antibody, IgM, CSF 0.79 AU or less: Negative - No significant level of IgM antibodies to measles (rubeola) virus detected.
0.80-1.20 AU: Equivocal - Repeat testing in 10-14 days may be helpful.
1.21 AU or greater: Positive - IgM antibodies to measles (rubeola) virus detected. Suggestive of current or recent infection or immunization. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.
0054442Mumps Virus Antibody IgG, CSF Effective August 20, 2012

8.9 AU/mL or less: Negative - No significant level of detectable IgG mumps virus antibody.
9.0-10.9 AU/mL: Equivocal - Repeat testing in 10-14 days may be helpful.
11.0 AU/mL or greater: Positive - IgG antibody to mumps virus detected, which may indicate a current or past mumps virus infection.
0054443Mumps Virus Antibody IgM, CSF 0.79 IV or less: Negative - No significant level of detectable IgM antibody to Mumps virus.
0.80-1.20 IV: Equivocal - Borderline levels of IgM antibody to Mumps virus. Repeat testing in 10-14 days may be helpful.
1.21 IV or greater: Positive - Presence of IgM antibody to Mumps virus detected, which may indicate a current or recent infection. However, low levels of IgM antibody may occasionally persist for more than 12 months post-infection or immunization.
0054444Varicella-Zoster Virus Antibody, IgG, CSF Effective August 20, 2012

134 IV or less: Negative - No significant level of IgG antibody to varicella-zoster virus detected.
135-165 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
166 IV or greater: Positive - IgG antibody to varicella-zoster virus detected, which may indicate a current or past varicella-zoster infection.
0054445Varicella-Zoster Virus Antibody, IgM by ELISA (CSF) 0.90 ISR or less: Negative - No significant level of IgM antibody to varicella-zoster virus detected.
0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 ISR or greater: Positive - Significant level of IgM antibody to varicella-zoster virus detected, which may indicate current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
0050408Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM by ELISA, CSF 0.89 IV or less: Negative - No significant level of detectable HSV IgM antibody.
0.90-1.09 IV: Equivocal - Questionable presence of IgM antibodies. Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - IgM antibody to HSV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
0050394Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG, CSF 0.89 IV or less: Negative - No significant level of detectable HSV IgG antibody.
0.90-1.09 IV: Equivocal - Questionable presence of IgG antibodies. Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - IgG antibody to HSV detected which may indicate a current or past HSV infection.
0050379Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by ELISA (HerpeSelect®), CSF 0.89 IV or less: Negative - No significant level of detectable IgG antibody to HSV type 1 glycoprotein G.
0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 1. Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past infection.
0050359Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA (HerpeSelect®), CSF 0.89 IV or less: Negative - No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 2. Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.
2001629Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgG, CSF < 1:1 Negative - No significant level of LCM virus IgG antibody detected.
≥ 1:1 Positive - Presence of IgG antibody to LCM virus detected, suggestive of current or past infection.
2001630Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgM, CSF < 1:1 Negative - No significant level of LCM virus IgM antibody detected.
≥ 1:1 Positive - Presence of IgM antibody to LCM virus detected, suggestive of current or past infection.

Interpretive Data: Refer to individual components for additional Interpretive Data.

Refer to Statement D under Testing Information at http://www.aruplab.com.
Note: If HSV 1 and/or 2 IgG, CSF is 1.10 IV or greater, then HSV 1 gG-Specific IgG, CSF and HSV 2 gG-Specific IgG, CSF will be added. Additional charges apply.
CPT Code(s): 86651 x2 CE G/M; 86652 x2 EEE G/M; 86653 x2 ST LE G/M; 86654 x2 WEE G/M; 86789 WNV IgG; 86788 WNV IgM; 86765 x2 Measles G/M; 86735 x2 Mumps G/M; 86787 x2 VZV G/M; 86727 x2 LCM G/M; 86694 HSV MC; 86694 HERP I/II; if reflexed, add 86695 HERP I; 86696 HERP II