ARUP's Laboratory Test Directory

Encephalitis Panel, CSF with Reflex to HSV Type 1 and 2 Glycoprotein G-Specific Ab, IgG : 2001741

Mnemonic: ENCEPHCSFR

Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody Semi-Quantitative Chemiluminescent Immunoassay
Performed: Tue, Fri
Reported: 2-6 days
Specimen Required: Collect: CSF.

Specimen Preparation: Transfer 3 mL CSF to an ARUP Standard Transport Tube. (Min: 2 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Serum or plasma. Contaminated or heat-inactivated specimens.

Stability (collection to initiation of testing): Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval:
Effective August 20, 2012
Test Number Components Reference Interval
0054440Measles (Rubeola) Antibody, IgG, CSF Effective August 20, 2012

24.9 AU/mL or less: Negative - No significant level of IgG antibody to measles (rubeola) virus detected.
25.0-29.9 AU/mL: Equivocal - Repeat testing in 10-14 days may be helpful.
30.0 AU/mL or greater: Positive - IgG antibody to measles (rubeola) detected, which may indicate a current or past measles (rubeola) infection.
0054441Measles (Rubeola) Antibody, IgM, CSF 0.79 AU or less: Negative - No significant level of IgM antibodies to measles (rubeola) virus detected.
0.80-1.20 AU: Equivocal - Repeat testing in 10-14 days may be helpful.
1.21 AU or greater: Positive - IgM antibodies to measles (rubeola) virus detected. Suggestive of current or recent infection or immunization. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.
0054442Mumps Virus Antibody IgG, CSF Effective August 20, 2012

8.9 AU/mL or less: Negative - No significant level of detectable IgG mumps virus antibody.
9.0-10.9 AU/mL: Equivocal - Repeat testing in 10-14 days may be helpful.
11.0 AU/mL or greater: Positive - IgG antibody to mumps virus detected, which may indicate a current or past mumps virus infection.
0054443Mumps Virus Antibody IgM, CSF 0.79 IV or less: Negative - No significant level of detectable IgM antibody to Mumps virus.
0.80-1.20 IV: Equivocal - Borderline levels of IgM antibody to Mumps virus. Repeat testing in 10-14 days may be helpful.
1.21 IV or greater: Positive - Presence of IgM antibody to Mumps virus detected, which may indicate a current or recent infection. However, low levels of IgM antibody may occasionally persist for more than 12 months post-infection or immunization.
0054444Varicella-Zoster Virus Antibody, IgG, CSF Effective August 20, 2012

134 IV or less: Negative - No significant level of IgG antibody to varicella-zoster virus detected.
135-165 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
166 IV or greater: Positive - IgG antibody to varicella-zoster virus detected, which may indicate a current or past varicella-zoster infection.
0054445Varicella-Zoster Virus Antibody, IgM by ELISA (CSF) 0.90 ISR or less: Negative - No significant level of IgM antibody to varicella-zoster virus detected.
0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 ISR or greater: Positive - Significant level of IgM antibody to varicella-zoster virus detected, which may indicate current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
0050408Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM by ELISA, CSF 0.89 IV or less: Negative - No significant level of detectable HSV IgM antibody.
0.90-1.09 IV: Equivocal - Questionable presence of IgM antibodies. Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - IgM antibody to HSV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
0050394Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG, CSF 0.89 IV or less: Negative - No significant level of detectable HSV IgG antibody.
0.90-1.09 IV: Equivocal - Questionable presence of IgG antibodies. Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - IgG antibody to HSV detected which may indicate a current or past HSV infection.
0050379Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF 0.89 IV or less: Negative - No significant level of detectable IgG antibody to HSV type 1 glycoprotein G.
0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 1. Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past infection.
0050359Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF 0.89 IV or less: Negative - No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 2. Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.
2001629Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgG, CSF < 1:1 Negative - No significant level of LCM virus IgG antibody detected.
≥ 1:1 Positive - Presence of IgG antibody to LCM virus detected, suggestive of current or past infection.
2001630Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgM, CSF < 1:1 Negative - No significant level of LCM virus IgM antibody detected.
≥ 1:1 Positive - Presence of IgM antibody to LCM virus detected, suggestive of current or past infection.

Interpretive Data:

See Compliance Statement B: www.aruplab.com/CS
Note: If HSV 1 and/or 2 IgG, CSF is 1.10 IV or greater, then HSV 1 gG-Specific IgG, CSF and HSV 2 gG-Specific IgG, CSF will be added. Additional charges apply.
CPT Code(s): 86765; 86765; 86735; 86735; 86787; 86787; 86727 x2; 86694; 86694; if reflexed, add 86695; 86696