ARUP's Laboratory Test Directory

Neisseria meningitidis Tetravalent Antibodies (Serogroups A, C, W-135, & Y), IgG : 2001603

Mnemonic: NMENING

Methodology: Multi-Analyte Fluorescent Detection
Performed: Mon
Reported: 1-8 days
Specimen Required: Collect: One 4 mL serum separator tube.

Storage/Transport Temperature: 1 mL serum frozen (Min: 0.2 mL). Submit specimen in an ARUP Standard Transport Tube.

Unacceptable Conditions: Ambient or refrigerated temperatures.

Stability (collection to initiation of testing): After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 year
Reference Interval:
N. meningitidis A, C, W-135, Y, IgG:
0.9 µg/mL or less: Antibody concentration not protective.
1.0-2.0 µg/mL: Equivocal.
2.1 µg/mL or greater: Antibody to Neisseria meningitidis detected. Suggestive of protection.

Responder status is determined according to the ratio of the one month post-vaccination concentration to pre-vaccination concentration of IgG antibodies to N. meningitidis (Types A, C, Y, and W-135) as follows:

1. If the one month post-vaccination concentration is less than 3.0 µg/mL, the patient is considered to be a non-responder.
2. If the one month post-vaccination concentration is greater than or equal to 3.0 µg/mL, a patient with a ratio of greater than or equal to 4 is a good responder, a ratio of  2-4 is a weak responder, and a ratio of less than 2 is considered a non-responder
CPT Code(s): 86741 x4
Cross References: Neisseria Meningitidis IgG , Vaccine resonse, Vaccine resonse
 
 

 

 

 
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