ARUP's Laboratory Test Directory

Hepatitis B Virus Genotyping : 2001567

Mnemonic: HBVGENO

Methodology: Polymerase Chain Reaction/Sequencing
Performed: Tue
Reported: Within 10 days
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), serum separator tube, or plasma preparation tube.

Specimen Preparation: Separate serum or plasma from cells within 24 hours. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature: Frozen.

Remarks: Please submit most recent viral load and test date, if available.

Unacceptable Conditions: Heparinized specimens.

Stability (collection to initiation of testing): On cells: Ambient: 24 hours. After separation from cells: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 6 weeks
Reference Interval:
None
Interpretive Data: Both the HBV RT polymerase and the HBsAg encoding regions are sequenced. Resistance and surface antigen mutations are reported. In addition, the eight major HBV genotypes (A, B, C, D, E, F, G and H) are identified. Mutations in viral sub-populations below 20 percent of total may not be detected.

This test is performed pursuant to a license agreement with Roche Molecular Systems, Inc.

See Compliance Statement B: www.aruplab.com/CS
Note: This test may be unsuccessful if the HBV viral load is less than log 3.0 or 1,000 IU/mL of plasma.
CPT Code(s): 87912
Cross References: HBV Resistance, HBV Type (Hepatitis B Virus Genotype), Hepatitis B Drug Resistance Panel (Hepatitis B Virus Genotype)