ARUP's Laboratory Test Directory

0099528: ssDNA Antibody, IgG

Test Mnemonic: DNA SS
Methodology: Enzyme-Linked Immunosorbent Assay

Performed: Tue, Thu, Sat

Reported: 1-4 days

Specimen Required:  
Collect: One 4 mL SST.

Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.15 mL serum at 2-8°C.

Remarks: Separate serum from cells ASAP.

Unacceptable Conditions: Plasma.  Severely lipemic, contaminated, or hemolyzed specimens.

Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval:
< 20 EU: Negative
20-25 EU: Borderline positive
> 25 EU: Positive

Note:
The ssDNA antibody test detects ssDNA and some dsDNA antibodies.  As a result, patient samples should also be tested for dsDNA antibodies in order to more accurately determine the level of anti-ssDNA antibodies.  By calculating the ratio (ssDNA/dsDNA), a conclusion can be made as to the presence of ssDNA antibodies.  A ratio less than or equal to 1.0 indicates the absence of ssDNA antibodies.  A ratio greater than 1.0 indicates the presence of ssDNA antibodies.

CPT Code(s):
86226

 

 

 
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