ARUP's Laboratory Test Directory

0099359: Helicobacter pylori Antibody, IgG

Test Mnemonic: G PYLORI
Methodology: Enzyme Immunoassay

Performed: Sun-Sat

Reported: Within 24 hours

Specimen Required:  
Collect: One 4 mL SST, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Transport: 0.5 mL serum or plasma at 2-8°C. (Min: 0.3 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.1 mL serum or plasma at 2-8°C.

Remarks: Separate serum or plasma from cells ASAP.

Unacceptable Conditions: Severely lipemic, contaminated, heat-inactivated, or hemolyzed specimens.

Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval:
1.7 EV or less: Negative - No significant level of IgG antibody to H. pylori detected.
1.8-2.2 EV: Equivocal - Repeat testing in 10-14 days may be helpful.
2.3 EV or greater: Positive - IgG antibody to H. pylori detected, suggestive of previous exposure or active infection.

Interpretive Data:
Previously known as Campylobacter pylori, Helicobacter pylori-specific antibodies are detectable in almost all adult patients with duodenal ulcer and about 80% of patients with gastric ulcer. The prevalence of H. pylori antibodies increases with age and can be found in a significant percentage of healthy individuals over the age of 50. Positive results do not confirm the diagnosis of H. pylori-associated gastritis or duodenal ulcer, but negative results are strong evidence against these diagnoses.



CPT Code(s):
86677

 

 

 
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