ARUP's Laboratory Test Directory

Helicobacter pylori Antibody, IgG : 0099359

Mnemonic: G PYLORI

Methodology: Semi-Quantitative Enzyme Immunoassay
Performed: Sun-Sat
Reported: Within 24 hours
Specimen Required: Collect: Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
1.7 EV or less: Negative - No significant level of IgG antibody to H. pylori detected.
1.8-2.2 EV: Equivocal - Repeat testing in 10-14 days may be helpful.
2.3 EV or greater: Positive - IgG antibody to H. pylori detected, suggestive of previous exposure or active infection.
Interpretive Data: Previously known as Campylobacter pylori, Helicobacter pylori-specific antibodies are detectable in almost all adult patients with duodenal ulcer and about 80% of patients with gastric ulcer. The prevalence of H. pylori antibodies increases with age and can be found in a significant percentage of healthy individuals over the age of 50. Positive results do not confirm the diagnosis of H. pylori-associated gastritis or duodenal ulcer, but negative results are strong evidence against these diagnoses.

For additional information, refer to Helicobacter pylori topic at arupconsult.com
CPT Code(s): 86677
Cross References: Camplyobacter (Helicobacter pylori Antibody, IgG)
 
 

 

 

 
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