ARUP's Laboratory Test Directory
| 0099249: Ribosomal P Protein Antibody |
| Test Mnemonic: RIBPP | |
|
Methodology: Multi-Analyte Fluorescent Detection
Performed: Sun-Sat Reported: 1-2 days |
| Specimen Required: | |
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Collect: One 4 mL SST.
Transport: 1 mL serum at 2-8°C. (Min: 0.2 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.5 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Unacceptable Conditions: Plasma and other body fluids. Severely lipemic or bacterially contaminated specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
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| Reference Interval: |
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29 AU/mL or less: Negative 30-40 AU/mL: Equivocal 41 AU/mL or greater: Positive |
| Interpretive Data: | |
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Autoantibodies reacting with cytoplasmic ribosomes are highly specific for systemic lupus erythematosus. Ribosomal-P antibodies are found in approximately 12% of patients with systemic lupus erythematosus (SLE) and in 90% of patients with lupus psychosis; titers often increase more than fivefold during and before active phases of psychosis.
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| CPT Code(s): | |
| 83516 |