ARUP's Laboratory Test Directory

Interleukin 2 by ELISA : 0099230

Mnemonic: IL2

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Second and fourth Tue
Reported: 1-21 days
Specimen Required: Collect:  One 6 mL serum separator tube, one 3 mL lavender (EDTA) or pink (K2EDTA), one 3 mL green (sodium or lithium heparin), or joint fluid.  Cell-free culture supernatants are also acceptable.

Transport:  1 mL serum, plasma, joint fluid, or cell-free culture supernatant, frozen. (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport:  0.3 mL serum, plasma, joint fluid, or cell-free culture supernatant, frozen.

Remarks:  CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. Separate serum, plasma, or fluid within 30 minutes from cells and freeze. Avoid freeze/thaw cycles.

Unacceptable Conditions:  Severely hemolyzed, contaminated, heat-inactivated, refrigerated, or lipemic specimens.

Stability:  After separation from cells: Ambient: 30 minutes; Refrigerated: Unacceptable; Frozen: 1 year
Reference Interval:
< 31.2 pg/mL
Interpretive Data:

Please refer to Statement D in the Compliance Statements section in the front of the Laboratory Test Directory.
Note: Interleukin 2 (IL-2) is a glycoprotein produced by activated T-cells that has a variety of immunologic functions, the most notable being the ability to promote the proliferation and maturation of activated T-cells. It has been known by various names, including T-Cell Growth Factor (TCGF), Thymocyte Stimulation Factor (TSF), Thymocyte Mitogenesis Factor (TMF), T-Cell Replacing Factor (TRF), and Killer Helper Factor (KHF).

Decreased production of this cytokine has been associated with the following disease states: systemic lupus erythematosus (SLE), Hodgkin disease, lepromatous leprosy, and AIDS. The ability of IL-2 to stimulate natural killer cells and enhance their cytotoxicity has led to the combined usage of IL-2 and LAK cells for the treatment of certain cancers.
CPT Code(s): 83520 
 
 

 

 

 
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