ARUP's Laboratory Test Directory

Sirolimus : 0098467

Mnemonic: RAPAMUNE

Methodology: Tandem Mass Spectrometry
Performed: Sun-Sat
Reported: Within 24 hours
Specimen Required: Collect:  One 3 mL lavender (EDTA) or pink (K2EDTA).

Storage/Transport Temperature:  3 mL whole blood at 2-8°C.  (Min: 0.25 mL)

Unacceptable Conditions:  Serum, plasma, and specimens ambient longer than 24 hours.

Stability (collection to initiation of testing):  Ambient: 24 hours; Refrigerated: 1 week; Frozen: 7 months
Interpretive Data: A therapeutic range of 4-12 ng/mL is proposed, based on a pre-dose (trough) steady-state specimen, concomitant cyclosporine, for a kidney transplant patient in the maintenance phase of therapy. A range of 12-20 ng/mL has been suggested for liver transplant. The range may vary with other transplant organs, when used in combination with drugs other than cyclosporine (or sirolimus alone), with the approach of the transplant center, and with other factors.
CPT Code(s): 80195
Cross References: Rapamune® , Rapamycin®
 
 

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org