ARUP's Laboratory Test Directory
| 0098467: Sirolimus |
| Test Mnemonic: RAPAMUNE | |
|
Methodology: Tandem Mass Spectrometry
Performed: Sun-Sat Reported: Within 24 hours |
| Specimen Required: | |
|
Collect: One 3 mL lavender (EDTA) or pink (K2EDTA).
Transport: 3 mL whole blood at 2-8°C. (Min: 1 mL) Pediatric Collection/Transport: 0.5 mL whole blood at 2-8°C. Unacceptable Conditions: Serum, plasma, and specimens ambient longer than 24 hours. Stability: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 7 months |
|
| Reference Interval: |
| Therapeutic Range: 4.0-12.0 ng/mL |
| Interpretive Data: | |
|
The stated therapeutic range is based on a trough specimen, with the patient in the maintenance phase, and sirolimus in combination with cyclosporine for a kidney transplant. A range of 12-20 ng/mL has been suggested for liver transplant. The range may vary with other transplant organs, when used in combination with drugs other than cyclosporine (or sirolimus alone), with the approach of the transplant center, and other factors.
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| CPT Code(s): | |
| 80195 |