ARUP's Laboratory Test Directory

Helicobacter pylori Antibody, IgM : 0098392

Mnemonic: M PYLORI

Ordering Recommendation: Do not use to diagnose H. pylori; order H. pylori urea breath test (0020646) or fecal antigen by EIA (0065147).
Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed: Sun-Sat
Reported: 1-3 days
Specimen Required: Collect: Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Contaminated, heat-activated, hemolyzed, or severely lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
0.8 EV or less: Negative - No significant level of IgM antibody to H. pylori detected.
0.9-1.1 EV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.2 EV or greater: Positive - IgM antibody to H. pylori detected, suggestive of active infection.
Interpretive Data: Gastric colonization by Helicobacter pylori has been implicated in the development of some cases of gastritis and peptic or duodenal ulcer. The clinical utility of H. pylori antibody, IgM measurement has not been clearly established.

For additional information, refer to Helicobacter pylori topic at arupconsult.com

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 86677
Cross References: Camplyobacter (Helicobacter pylori Antibody, IgM)