ARUP's Laboratory Test Directory
| 0097709: Tissue Transglutaminase Antibody, IgA |
| Test Mnemonic: TTG | |
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#ExistMethodology>
Methodology: Enzyme-Linked Immunosorbent Assay
*ExistMethodology> #ExistPerformed> Performed: Sun-Sat *ExistPerformed> #ExistReported> Reported: 1-2 days *ExistReported> |
| Specimen Required: | |
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#ExistCollect>
Collect: One 4 mL SST.
*ExistCollect> #ExistTransport> Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. *ExistTransport> #ExistPedCollectTransport> Pediatric Collection/Transport: 0.15 mL serum at 2-8°C. *ExistPedCollectTransport> #ExistRemarks> Remarks: Separate serum from cells ASAP. *ExistRemarks> #ExistConditions> Unacceptable Conditions: Plasma and other body fluids. Severely lipemic, contaminated, and hemolyzed specimens. *ExistConditions> #ExistStability> Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) *ExistStability> |
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| Reference Interval: |
| #ExistRefRange> 19 Units or less *ExistRefRange> |
| Interpretive Data: | |
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#ExistInterpData>
IgA antibody against human tTG, if detected at a level greater than 19 units, may suggest the possibility of certain gluten sensitive enteropathies such as celiac disease and dermatitis herpetiformis.
*ExistInterpData> |
| Note: | |
| The endomysial antigen has been identified as the protein cross-linking enzyme known as tissue transglutaminase. Detection of tissue transglutaminase antibodies is an aid in the diagnosis of certain gluten-sensitive enteropathies, such as celiac disease and dermatitis herpetiformis. Human tTG antigen is utilized in this assay. |
| CPT Code(s): | |
| 83516 |