ARUP's Laboratory Test Directory
| 0097709: Tissue Transglutaminase Antibody, IgA |
| Test Mnemonic: TTG | |
|
Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun-Sat Reported: 1-2 days |
| Specimen Required: | |
|
Collect: One 4 mL SST.
Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.15 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Unacceptable Conditions: Plasma and other body fluids. Severely lipemic, contaminated, and hemolyzed specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
|
| Reference Interval: |
| 19 Units or less |
| Interpretive Data: | |
|
IgA antibody against human tTG, if detected at a level greater than 19 units, may suggest the possibility of certain gluten sensitive enteropathies such as celiac disease and dermatitis herpetiformis.
|
| Note: | |
| The endomysial antigen has been identified as the protein cross-linking enzyme known as tissue transglutaminase. Detection of tissue transglutaminase antibodies is an aid in the diagnosis of certain gluten-sensitive enteropathies, such as celiac disease and dermatitis herpetiformis. Human tTG antigen is utilized in this assay. |
| CPT Code(s): | |
| 83516 |