ARUP's Laboratory Test Directory
| 0097615: Chromosome Analysis, FISH-Metaphase |
![[ image for: Time Sensitive]](icon_1.jpg){kind=icon} | Time Sensitive | ![[ image for: Patient History For Cytogenetics (Chromosome) Studies]](icon_20.jpg){kind=icon} | Patient History For Cytogenetics (Chromosome) Studies |
| Test Mnemonic: CHROMOFISH | |
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Methodology: Fluorescence in situ Hybridization
Performed: On request Reported: Varies |
| Specimen Required: | |
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Collect: One 10 mL green (sodium heparin). Also acceptable: 3 mL non-diluted bone marrow aspirate collected in a heparinized syringe and transferred into a green (sodium heparin). Other specimen types may be acceptable.
Transport: 10 mL whole blood or 3 mL bone marrow at 20-25°C. (Min: 5 mL whole blood or 1 mL bone marrow) Remarks: It is recommended that all FISH studies be done in conjunction with routine cytogenetic analysis. (Refer to appropriate Chromosome Analysis test for order instructions). If FISH only is requested, please include copy of previous cytogenetics report. If dropped cytogenetics slides or cell pellets are not submitted, a processing fee will apply. Unacceptable Conditions: Frozen, clotted, or paraffin-embedded specimens. Stability: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable |
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| Reference Interval: |
| By report |
| Note: | |
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Fluorescence in situ hybridization (FISH) is performed for specific abnormalities as follows: Microdeletion syndromes (e.g., Prader-Willi, Angelman, DiGeorge, Williams), Marker chromosome identification,and subtelomeric screening Time of culture as well as testing, can vary depending on sample type and probes ordered. This test must be ordered using a Cytogenetic test request form 43097 or through your ARUP interface. Please submit the Patient History Form - Chromosome Studies with the Electronic Packing List, available on ARUP's Web site, http://www.aruplab.com/home/consent_forms.jsp. A processing fee will be charged if this procedure is canceled at the client's request, after the test has been set up, or if the sample integrity is inadequate to allow culture growth. The fee will vary based on sample type. |
| CPT Code(s): | |
| 88271 DNA probe each; 88273 Chromosomal in situ hybridization 10-30 cells each; 88291 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders. |